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Treating Life-Threatening Myocarditis by Blocking Interleukin-1

Critical care medicine, 2016-08, Vol.44 (8), p.e751-e754

2016

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Effects of Gevokizumab on Glycemia and Inflammatory Markers in Type 2 Diabetes

Diabetes care, 2012-08, Vol.35 (8), p.1654-1662

2012

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Efficacy of canakinumab as first-line biologic agent in adult-onset Still's disease

Arthritis research & therapy, 2019-02, Vol.21 (1), p.54-54, Article 54

2019

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Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans

Blood, 2015-01, Vol.125 (5), p.815-819

2015

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Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT

Blood, 2017-10, Vol.130 (15), p.1760-1767

2017

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α-1-Antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood

Journal of leukocyte biology, 2009-05, Vol.85 (5), p.886-895

2009

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Interleukin-1 Blockade With Anakinra to Prevent Adverse Cardiac Remodeling After Acute Myocardial Infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot Study)

The American journal of cardiology, 2010-05, Vol.105 (10), p.1371-1377.e1

2010

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Circulating interleukin-38 concentrations in healthy adults

Frontiers in immunology, 2022-08, Vol.13, p.964365-964365

2022

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Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial

Critical care medicine, 2016-02, Vol.44 (2), p.275-281

2016

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Interleukin‐32: A new proinflammatory cytokine involved in hepatitis C virus‐related liver inflammation and fibrosis

Hepatology (Baltimore, Md.), 2011-06, Vol.53 (6), p.1819-1829

2011

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Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells

JCI insight, 2021-04, Vol.6 (7)

2021

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Normal free interleukin-18 (IL-18) plasma levels in dengue virus infection and the need to measure both total IL-18 and IL-18 binding protein levels

Clinical and vaccine immunology, 2015-06, Vol.22 (6), p.650-655

2015

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Safety and Efficacy of Anakinra in Severe Hidradenitis Suppurativa: A Randomized Clinical Trial

JAMA dermatology (Chicago, Ill.), 2016-01, Vol.152 (1), p.52

2016

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Treating pulmonary silicosis by blocking interleukin 1

American journal of respiratory and critical care medicine, 2015-03, Vol.191 (5), p.596-598

2015

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Interleukin-1β-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Behçet's disease: an open-label pilot study

Annals of the rheumatic diseases, 2012-04, Vol.71 (4), p.563-566

2012

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Anakinra treatment in drug-resistant Behcet’s disease: a case series

Clinical rheumatology, 2015-07, Vol.34 (7), p.1293-1301

2015

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Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

Annals of the rheumatic diseases, 2016-03, Vol.75 (3), p.593-600

2016

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The Inter-Relationship of Platelets with Interleukin-1β-Mediated Inflammation in Humans

Thrombosis and haemostasis, 2018-12, Vol.118 (12), p.2112-2125

2018

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α1-Antitrypsin Therapy Downregulates Toll-Like Receptor-Induced IL-1β Responses in Monocytes and Myeloid Dendritic Cells and May Improve Islet Function in Recently Diagnosed Patients With Type 1 Diabetes

The journal of clinical endocrinology and metabolism, 2014-08, Vol.99 (8), p.E1418-E1426

2014

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Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat)

Molecular medicine (Cambridge, Mass.), 2011-05, Vol.17 (5-6), p.353-362

2011

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Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial

Annals of internal medicine, 2017-04, Vol.166 (8), p.557

2017

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Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome

Blood, 2005-11, Vol.106 (10), p.3483-3489

2005

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High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein

Journal of autoimmunity, 2010-03, Vol.34 (2), p.121-126

2010

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Physiological levels of interleukin-18 stimulate multiple neutrophil functions through p38 MAP kinase activation

Journal of leukocyte biology, 2002-08, Vol.72 (2), p.401-409

2002

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Treating Life-Threatening Myocarditis by Blocking Interleukin-1

Effects of Gevokizumab on Glycemia and Inflammatory Markers in Type 2 Diabetes

Efficacy of canakinumab as first-line biologic agent in adult-onset Still's disease

Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans

Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT

α-1-Antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood

Interleukin-1 Blockade With Anakinra to Prevent Adverse Cardiac Remodeling After Acute Myocardial Infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot Study)

Circulating interleukin-38 concentrations in healthy adults

Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial

Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial

Interleukin‐32: A new proinflammatory cytokine involved in hepatitis C virus‐related liver inflammation and fibrosis

Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells

Normal free interleukin-18 (IL-18) plasma levels in dengue virus infection and the need to measure both total IL-18 and IL-18 binding protein levels

Safety and Efficacy of Anakinra in Severe Hidradenitis Suppurativa: A Randomized Clinical Trial

Treating pulmonary silicosis by blocking interleukin 1

Interleukin-1β-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Behçet's disease: an open-label pilot study

Anakinra treatment in drug-resistant Behcet’s disease: a case series

Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

The Inter-Relationship of Platelets with Interleukin-1β-Mediated Inflammation in Humans

α1-Antitrypsin Therapy Downregulates Toll-Like Receptor-Induced IL-1β Responses in Monocytes and Myeloid Dendritic Cells and May Improve Islet Function in Recently Diagnosed Patients With Type 1 Diabetes

Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat)

Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial

Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome

High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein

Physiological levels of interleukin-18 stimulate multiple neutrophil functions through p38 MAP kinase activation

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