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The Opportunities and Challenges of Peroxisome Proliferator-Activated Receptors Ligands in Clinical Drug Discovery and Development

International journal of molecular sciences, 2018-07, Vol.19 (8), p.2189

2018

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PPARs as Nuclear Receptors for Nutrient and Energy Metabolism

Molecules (Basel, Switzerland), 2019-07, Vol.24 (14), p.2545

2019

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The Role of PPAR and Its Cross-Talk with CAR and LXR in Obesity and Atherosclerosis

International journal of molecular sciences, 2018-04, Vol.19 (4), p.1260

2018

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High-Protein Diet Induces Hyperuricemia in a New Animal Model for Studying Human Gout

International journal of molecular sciences, 2020-03, Vol.21 (6), p.2147

2020

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Comparative Gene Identification-58 (CGI-58) Promotes Autophagy as a Putative Lysophosphatidylglycerol Acyltransferase

The Journal of biological chemistry, 2014-11, Vol.289 (47), p.33044-33053

2014

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Celastrol inhibits store operated calcium entry and suppresses psoriasis

Frontiers in pharmacology, 2023-02, Vol.14, p.1111798-1111798

2023

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Melatonin Attenuates Dextran Sodium Sulfate Induced Colitis in Obese Mice

Pharmaceuticals (Basel, Switzerland), 2021-08, Vol.14 (8), p.822

2021

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Microbiome Remodeling via the Montmorillonite Adsorption-Excretion Axis Prevents Obesity-related Metabolic Disorders

EBioMedicine, 2017-02, Vol.16 (C), p.251-261

2017

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Activation of human stearoyl-coenzyme A desaturase 1 contributes to the lipogenic effect of PXR in HepG2 cells

PloS one, 2013-07, Vol.8 (7), p.e67959-e67959

2013

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Mdb1, a fission yeast homolog of human MDC1, modulates DNA damage response and mitotic spindle function

PloS one, 2014-05, Vol.9 (5), p.e97028

2014

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Therapeutic potential of melatonin in colorectal cancer: Focus on lipid metabolism and gut microbiota

Biochimica et biophysica acta. Molecular basis of disease, 2022-01, Vol.1868 (1), p.166281-166281, Article 166281

2022

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DBZ is a putative PPARγ agonist that prevents high fat diet-induced obesity, insulin resistance and gut dysbiosis

Biochimica et biophysica acta. General subjects, 2017-11, Vol.1861 (11), p.2690-2701

2017

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Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

Gastroenterology (New York, N.Y. 1943), 2008-02, Vol.134 (2), p.556-567.e1

2008

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Preventive obesity agent montmorillonite adsorbs dietary lipids and enhances lipid excretion from the digestive tract

Scientific reports, 2016-02, Vol.6 (1), p.19659-19659, Article 19659

2016

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Combination exposure of melamine and cyanuric acid is associated with polyuria and activation of NLRP3 inflammasome in rats

American journal of physiology. Renal physiology, 2018-08, Vol.315 (2), p.F199-F210

2018

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Genotoxic stress causes the accumulation of DNA‐dependent protein kinase catalytic subunit phosphorylated at serine 2056 at nuclear speckles and alters pre‐mRNA alternative splicing

FEBS open bio, 2019-02, Vol.9 (2), p.304-314

2019

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Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase

The Journal of biological chemistry, 2015-01, Vol.290 (1), p.241-241

2015

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CHIP functions an E3 ubiquitin ligase of Runx1

Biochemical and biophysical research communications, 2009-08, Vol.386 (1), p.242-246

2009

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p15RS Attenuates Wnt/β-Catenin Signaling by Disrupting β-Catenin·TCF4 Interaction

The Journal of biological chemistry, 2010-11, Vol.285 (45), p.34621-34631

2010

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Mature adipocytes observed to undergo reproliferation and polyploidy

FEBS open bio, 2017-05, Vol.7 (5), p.652-658

2017

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ROR[alpha] inhibits adipocyte-conditioned medium-induced colorectal cancer cell proliferation and migration and chick embryo chorioallantoic membrane angiopoiesis

American Journal of Physiology: Cell Physiology, 2015-03, Vol.308 (5), p.C385

2015

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Functional crosstalk of CAR-LXR and ROR-LXR in drug metabolism and lipid metabolism: Development of Novel Therapeutic Strategy by Regulating the Nuclear Hormone Receptors

Advanced drug delivery reviews, 2010, Vol.62 (13), p.1316-1321

2010

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Biology of PXR: role in drug-hormone interactions

EXCLI journal, 2014-01, Vol.13, p.728-739

2014

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Varp interacts with Rab38 and functions as its potential effector

Biochemical and biophysical research communications, 2008-07, Vol.372 (1), p.162-167

2008

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A Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic ResponsesS

Molecular pharmacology, 2010-10, Vol.78 (4), p.666-674

2010

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The Opportunities and Challenges of Peroxisome Proliferator-Activated Receptors Ligands in Clinical Drug Discovery and Development

PPARs as Nuclear Receptors for Nutrient and Energy Metabolism

The Role of PPAR and Its Cross-Talk with CAR and LXR in Obesity and Atherosclerosis

High-Protein Diet Induces Hyperuricemia in a New Animal Model for Studying Human Gout

Comparative Gene Identification-58 (CGI-58) Promotes Autophagy as a Putative Lysophosphatidylglycerol Acyltransferase

Celastrol inhibits store operated calcium entry and suppresses psoriasis

Melatonin Attenuates Dextran Sodium Sulfate Induced Colitis in Obese Mice

Microbiome Remodeling via the Montmorillonite Adsorption-Excretion Axis Prevents Obesity-related Metabolic Disorders

Activation of human stearoyl-coenzyme A desaturase 1 contributes to the lipogenic effect of PXR in HepG2 cells

Mdb1, a fission yeast homolog of human MDC1, modulates DNA damage response and mitotic spindle function

Therapeutic potential of melatonin in colorectal cancer: Focus on lipid metabolism and gut microbiota

DBZ is a putative PPARγ agonist that prevents high fat diet-induced obesity, insulin resistance and gut dysbiosis

Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

Preventive obesity agent montmorillonite adsorbs dietary lipids and enhances lipid excretion from the digestive tract

Combination exposure of melamine and cyanuric acid is associated with polyuria and activation of NLRP3 inflammasome in rats

Genotoxic stress causes the accumulation of DNA‐dependent protein kinase catalytic subunit phosphorylated at serine 2056 at nuclear speckles and alters pre‐mRNA alternative splicing

Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase

CHIP functions an E3 ubiquitin ligase of Runx1

p15RS Attenuates Wnt/β-Catenin Signaling by Disrupting β-Catenin·TCF4 Interaction

Mature adipocytes observed to undergo reproliferation and polyploidy

ROR[alpha] inhibits adipocyte-conditioned medium-induced colorectal cancer cell proliferation and migration and chick embryo chorioallantoic membrane angiopoiesis

Functional crosstalk of CAR-LXR and ROR-LXR in drug metabolism and lipid metabolism: Development of Novel Therapeutic Strategy by Regulating the Nuclear Hormone Receptors

Biology of PXR: role in drug-hormone interactions

Varp interacts with Rab38 and functions as its potential effector

A Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic ResponsesS

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