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Structural Basis of Arc Binding to Synaptic Proteins: Implications for Cognitive Disease

Neuron (Cambridge, Mass.), 2015-04, Vol.86 (2), p.490-500

2015

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Increased Expression of the Immediate-Early Gene Arc/Arg3.1 Reduces AMPA Receptor-Mediated Synaptic Transmission

Neuron (Cambridge, Mass.), 2006-11, Vol.52 (3), p.461-474

2006

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Homer1a drives homeostatic scaling-down of excitatory synapses during sleep

Science (American Association for the Advancement of Science), 2017-02, Vol.355 (6324), p.511-515

2017

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Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ

Cell, 2012-05, Vol.149 (4), p.886-898

2012

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Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission

The Journal of neuroscience, 2013-11, Vol.33 (47), p.18448-18468

2013

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SOAR and the polybasic STIM1 domains gate and regulate Orai channels

Nature cell biology, 2009-03, Vol.11 (3), p.337-343

2009

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Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy

Science translational medicine, 2018-06, Vol.10 (447)

2018

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STIM1 Regulates Somatic Ca2+ Signals and Intrinsic Firing Properties of Cerebellar Purkinje Neurons

The Journal of neuroscience, 2017-09, Vol.37 (37), p.8876-8894

2017

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Homer1a Is Required for Establishment of Contralateral Bias and Maintenance of Ocular Dominance in Mouse Visual Cortex

The Journal of neuroscience, 2019-05, Vol.39 (20), p.3897-3905

2019

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STIM1 carboxyl-terminus activates native SOC, Icrac and TRPC1 channels

Nature cell biology, 2006-09, Vol.8 (9), p.1003-1010

2006

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Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model

Science translational medicine, 2013-09, Vol.5 (201), p.201ra120

2013

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Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation

Molecular cell, 2019-07, Vol.75 (1), p.13-25.e5

2019

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An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs

FEBS letters, 2010-05, Vol.584 (10), p.2022-2027

2010

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Deficiency of SHANK3 isoforms impairs thermal hyperalgesia and dysregulates the expression of postsynaptic proteins in the spinal cord

Neuroscience research, 2021-02, Vol.163, p.26-33

2021

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Neuronal pentraxin 2 is required for facilitating excitatory synaptic inputs onto spinal neurons involved in pruriceptive transmission in a model of chronic itch

Nature communications, 2022-05, Vol.13 (1), p.2367-2367, Article 2367

2022

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Tagging active neurons by soma-targeted Cal-Light

Nature communications, 2022-12, Vol.13 (1), p.7692-7692, Article 7692

2022

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Synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons

Proceedings of the National Academy of Sciences - PNAS, 2009-01, Vol.106 (1), p.316-321

2009

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Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors

Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (14), p.6055-6060

2007

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Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1

The Journal of biological chemistry, 2009-04, Vol.284 (15), p.9733-9741

2009

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RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia

Biochemical and biophysical research communications, 2022-09, Vol.621, p.74-79

2022

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Molecular determinants of fast Ca²⁺-dependent inactivation and gating of the Orai channels

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (34), p.14687-14692

2009

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Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade

Cell reports (Cambridge), 2015-02, Vol.10 (5), p.684-693

2015

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Selective Targeting of Newly Synthesized Arc mRNA to Active Synapses Requires NMDA Receptor Activation

Neuron (Cambridge, Mass.), 2001-04, Vol.30 (1), p.227-240

2001

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Neuronal activity regulates glutamate transporter dynamics in developing astrocytes

Glia, 2012-02, Vol.60 (2), p.175-188

2012

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Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis

Cell reports (Cambridge), 2023-07, Vol.42 (7), p.112801-112801, Article 112801

2023

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Structural Basis of Arc Binding to Synaptic Proteins: Implications for Cognitive Disease

Increased Expression of the Immediate-Early Gene Arc/Arg3.1 Reduces AMPA Receptor-Mediated Synaptic Transmission

Homer1a drives homeostatic scaling-down of excitatory synapses during sleep

Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ

Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy

STIM1 Regulates Somatic Ca2+ Signals and Intrinsic Firing Properties of Cerebellar Purkinje Neurons

Homer1a Is Required for Establishment of Contralateral Bias and Maintenance of Ocular Dominance in Mouse Visual Cortex

STIM1 carboxyl-terminus activates native SOC, Icrac and TRPC1 channels

Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model

Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation

An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs

Deficiency of SHANK3 isoforms impairs thermal hyperalgesia and dysregulates the expression of postsynaptic proteins in the spinal cord

Neuronal pentraxin 2 is required for facilitating excitatory synaptic inputs onto spinal neurons involved in pruriceptive transmission in a model of chronic itch

Tagging active neurons by soma-targeted Cal-Light

Synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons

Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors

Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1

RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia

Molecular determinants of fast Ca²⁺-dependent inactivation and gating of the Orai channels

Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade

Selective Targeting of Newly Synthesized Arc mRNA to Active Synapses Requires NMDA Receptor Activation

Neuronal activity regulates glutamate transporter dynamics in developing astrocytes

Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis

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