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Site-Directed Mutagenesis of Cytochrome P450 2D6 and 2C19 Enzymes: Expression and Spectral Characterization of Naturally Occurring Allelic Variants

Applied biochemistry and biotechnology, 2018-09, Vol.186 (1), p.132-144

2018

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Cytochrome P450 genotype‐guided drug therapies: An update on current states

Clinical and experimental pharmacology & physiology, 2018-10, Vol.45 (10), p.991-1001

2018

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Cytochromes P450: Role in Carcinogenesis and Relevance to Cancers

Current drug metabolism, 2022-04, Vol.23 (5), p.355-373

2022

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The CYP2R1 Enzyme: Structure, Function, Enzymatic Properties and Genetic Polymorphism

Journal of pharmacy & pharmaceutical sciences, 2021, Vol.24, p.94-112

2021

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Current Updates On the In vivo Assessment of Zinc Oxide Nanoparticles Toxicity Using Animal Models

BioNanoScience, 2021-06, Vol.11 (2), p.590-620

2021

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Functional and structural characterisation of common cytochrome P450 2D6 allelic variants—roles of Pro34 and Thr107 in catalysis and inhibition

Naunyn-Schmiedeberg's archives of pharmacology, 2019-08, Vol.392 (8), p.1015-1029

2019

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In vitro effects of 95% khat ethanol extract (KEE) on human recombinant cytochrome P450 (CYP)1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2 and CYP3A5

Drug Metabolism and Personalized Therapy, 2021-08, Vol.37 (1), p.55-67

2021

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The xenobiotic inhibitor profile of cytochrome P4502C8

British journal of clinical pharmacology, 2000-12, Vol.50 (6), p.573-580

2000

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Functional Role of Ile264 in CYP2C8: Mutations Affect Haem Incorporation and Catalytic Activity

DRUG METABOLISM AND PHARMACOKINETICS, 2008-01, Vol.23 (3), p.165-174

2008

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Development and Validation of HPLC Methods for the Determination of CYP2D6 and CYP3A4 Activities

Current pharmaceutical analysis, 2012-09, Vol.8 (3), p.219-224

2012

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In vitro and in silico Approaches to Study Cytochrome P450-Mediated Interactions

Journal of pharmacy & pharmaceutical sciences, 2017-01, Vol.20 (1), p.319

2017

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In vitro and In silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5

Toxicology reports, 2022, Vol.9, p.759-768

2022

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Effect of 95% Ethanol Khat Extract and Cathinone on in vitro Human Recombinant Cytochrome P450 (CYP) 2C9, CYP2D6, and CYP3A4 Activity

European journal of drug metabolism and pharmacokinetics, 2019-06, Vol.44 (3), p.423-431

2019

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Cytochrome P450 2C9‐natural antiarthritic interactions: Evaluation of inhibition magnitude and prediction from in vitro data

Biopharmaceutics & drug disposition, 2018-04, Vol.39 (4), p.205-217

2018

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The Molecular and Enzyme Kinetic Basis for Altered Activity of Three Cytochrome P450 2C19 Variants Found in the Chinese Population

Current molecular pharmacology, 2020-01, Vol.13 (3), p.233-244

2020

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In vitro effect of important herbal active constituents on human cytochrome P450 1A2 (CYP1A2) activity

Phytomedicine (Stuttgart), 2014-10, Vol.21 (12), p.1645-1650

2014

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Heterologous expression of human cytochrome P450 (CYP) 2C19 in Escherichia coli and establishment of RP-HPLC method to serve as activity marker

Biomedical chromatography, 2013-07, Vol.27 (7), p.859-865

2013

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In vitro study of modulatory effects of extracts of Strobilanthes crispus on human cDNA-expressed cytochrome P450 2A6 (CYP2A6)

Drug metabolism and pharmacokinetics, 2017-01, Vol.32 (1), p.S67-S67

2017

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In vitro modulatory effects of flavonoids on human cytochrome P450 2C8 (CYP2C8)

Naunyn-Schmiedeberg's archives of pharmacology, 2012-05, Vol.385 (5), p.495-502

2012

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Functional characterization of cytochrome P450 2A6 allelic variants CYP2A615, CYP2A616, CYP2A621, and CYP2A622

Drug metabolism and disposition, 2010-05, Vol.38 (5), p.745-751

2010

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Effect of eurycomanone on cytochrome P450 isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 in vitro

Journal of natural medicines, 2014-04, Vol.68 (2), p.402-406

2014

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In vitro determination of the effect of Andrographis paniculata extracts and andrographolide on human hepatic cytochrome P450 activities

Journal of natural medicines, 2011-07, Vol.65 (3-4), p.440-447

2011

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Mechanism-based inactivation of cytochromes P450: implications in drug interactions and pharmacotherapy

Xenobiotica, 2024-08, Vol.54 (9), p.1-24

2024

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Cytochrome P450 2W1 (CYP2W1) - ready for use as the biomarker and drug target for cancer?

Xenobiotica, 2017-10, Vol.47 (10), p.923-932

2017

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In vitro inhibitory effects of glucosamine, chondroitin and diacerein on human hepatic CYP2D6

Drug Metabolism and Personalized Therapy, 2021-04, Vol.36 (4), p.259-270

2021

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Site-Directed Mutagenesis of Cytochrome P450 2D6 and 2C19 Enzymes: Expression and Spectral Characterization of Naturally Occurring Allelic Variants

Cytochrome P450 genotype‐guided drug therapies: An update on current states

Cytochromes P450: Role in Carcinogenesis and Relevance to Cancers

The CYP2R1 Enzyme: Structure, Function, Enzymatic Properties and Genetic Polymorphism

Current Updates On the In vivo Assessment of Zinc Oxide Nanoparticles Toxicity Using Animal Models

Functional and structural characterisation of common cytochrome P450 2D6 allelic variants—roles of Pro34 and Thr107 in catalysis and inhibition

In vitro effects of 95% khat ethanol extract (KEE) on human recombinant cytochrome P450 (CYP)1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2 and CYP3A5

The xenobiotic inhibitor profile of cytochrome P4502C8

Functional Role of Ile264 in CYP2C8: Mutations Affect Haem Incorporation and Catalytic Activity

Development and Validation of HPLC Methods for the Determination of CYP2D6 and CYP3A4 Activities

In vitro and in silico Approaches to Study Cytochrome P450-Mediated Interactions

In vitro and In silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5

Effect of 95% Ethanol Khat Extract and Cathinone on in vitro Human Recombinant Cytochrome P450 (CYP) 2C9, CYP2D6, and CYP3A4 Activity

Cytochrome P450 2C9‐natural antiarthritic interactions: Evaluation of inhibition magnitude and prediction from in vitro data

The Molecular and Enzyme Kinetic Basis for Altered Activity of Three Cytochrome P450 2C19 Variants Found in the Chinese Population

In vitro effect of important herbal active constituents on human cytochrome P450 1A2 (CYP1A2) activity

Heterologous expression of human cytochrome P450 (CYP) 2C19 in Escherichia coli and establishment of RP-HPLC method to serve as activity marker

In vitro study of modulatory effects of extracts of Strobilanthes crispus on human cDNA-expressed cytochrome P450 2A6 (CYP2A6)

In vitro modulatory effects of flavonoids on human cytochrome P450 2C8 (CYP2C8)

Functional characterization of cytochrome P450 2A6 allelic variants CYP2A615, CYP2A616, CYP2A621, and CYP2A622

Effect of eurycomanone on cytochrome P450 isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 in vitro

In vitro determination of the effect of Andrographis paniculata extracts and andrographolide on human hepatic cytochrome P450 activities

Mechanism-based inactivation of cytochromes P450: implications in drug interactions and pharmacotherapy

Cytochrome P450 2W1 (CYP2W1) - ready for use as the biomarker and drug target for cancer?

In vitro inhibitory effects of glucosamine, chondroitin and diacerein on human hepatic CYP2D6

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