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Pharmacokinetic/pharmacodynamic modeling in drug development

Annual review of pharmacology and toxicology, 2000-01, Vol.40 (1), p.67-95

2000

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Good Practices in Model‐Informed Drug Discovery and Development: Practice, Application, and Documentation

CPT: pharmacometrics and systems pharmacology, 2016-03, Vol.5 (3), p.93-122

2016

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Modelling response time profiles in the absence of drug concentrations: definition and performance evaluation of the K-PD model

Journal of pharmacokinetics and pharmacodynamics, 2007-02, Vol.34 (1), p.57-85

2007

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Animal Health Modeling & Simulation Society: a new society promoting model-based approaches in veterinary pharmacology

Journal of Veterinary Pharmacology and Therapeutics, 2013-10, Vol.36 (5), p.417-419

2013

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Pharmacometrics: Opportunity for Reducing Disease Burden in the Developing World: The Case of Africa

CPT: pharmacometrics and systems pharmacology, 2013-08, Vol.2 (8), p.1-4

2013

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Modeling and Simulation to Optimize the Design and Analysis of Confirmatory Trials, Characterize Risk–Benefit, and Support Label Claims

CPT: pharmacometrics and systems pharmacology, 2013-02, Vol.2 (2), p.1-3

2013

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Population pharmacokinetics of ibandronate in Caucasian and Japanese healthy males and postmenopausal females

International journal of clinical pharmacology and therapeutics, 2006-12, Vol.44 (12), p.655-667

2006

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Practical experience and issues in designing and performing population pharmacokinetic/pharmacodynamic studies

European journal of clinical pharmacology, 1996, Vol.49 (4), p.251-254

1996

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Sparse sampling for assessment of drug exposure in toxicological studies

European journal of drug metabolism and pharmacokinetics, 1996-04, Vol.21 (2), p.105-111

1996

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Population approaches in drug development. Report on an expert meeting to discuss population pharmacokinetic/pharmacodynamic software

European journal of clinical pharmacology, 1994-06, Vol.46 (5), p.389-391

1994

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L’architecture religieuse en Allemagne entre 1220 et 1350

Bulletin monumental, 2010, Vol.168 (3), p.227-242

Schurr, Marc Carel

2010

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Recherches récentes sur le gothique tardif (1350-1550)

Bulletin monumental, 2010, Vol.168 (3), p.243-280

Nußbaum, Norbert

2010

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Effect of adrenalectomy and aldosterone on the modulation of mineralocorticoid receptors in rat kidney

The Journal of biological chemistry, 1981-01, Vol.256 (1), p.142-147

1981

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La méthode de la clairance rénale pour l'individualisation des posologies du lithium en routine hospitalière

Encéphale, 1984, Vol.10 (5), p.223-230

1984

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Physiologically based pharmacokinetic study on a cyclosporin derivative, SDZ IMM 125

Journal of pharmacokinetics and biopharmaceutics, 1994-10, Vol.22 (5), p.327-365

1994

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Cytoplasmic and nuclear uptake of aldosterone in toad bladder: a mathematical modeling approach

American Journal of Physiology: Cell Physiology, 1985-01, Vol.248 (1), p.C88-C101

1985

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Alternative Approaches to Estimation of Population Pharmacokinetic Parameters: Comparison with the Nonlinear Mixed-Effect Model

Drug metabolism reviews, 1984, Vol.15 (1-2), p.265-292

1984

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Application of Sparse Sampling Approaches in Rodent Toxicokinetics: A Prospective View

Drug information journal, 1994, Vol.28 (1), p.263-279

1994

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Clinical pharmacokinetic/pharmacodynamic and physiologically based pharmacokinetic modeling in new drug development: the capecitabine experience

Investigational new drugs, 2003-05, Vol.21 (2), p.195-223

2003

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An application of population pharmacokinetics to the clinical use of cyclosporine in bone marrow transplant patients

Transplantation proceedings, 1988-04, Vol.20 (2 Suppl 2), p.466-470

1988

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A Time-Lag Model for Pharmacokinetics of Drugs Subject to Enterohepatic Circulation

Journal of pharmaceutical sciences, 1982-03, Vol.71 (3), p.297-302

1982

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Cytoplasmic and nuclear uptake of aldosterone in toad bladder: a mathematical modeling approach

American Journal of Physiology: Cell Physiology, 1985, Vol.17 (1), p.C88-C101

1985

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Can compartment models account for nonmonotonicity in pharmacokinetics?

Mathematical biosciences, 1982, Vol.58 (1), p.19-25

1982

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Finite element simulation of gas transport in proximal respiratory airways: Comparison with experimental data

Computers and biomedical research, 1981-12, Vol.14 (6), p.493-505

1981

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Bioequivalence of dosage forms. The confidence interval approach. Westlake's method (author's transl)

Therapie, 1980-11, Vol.35 (6), p.743

1980

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Pharmacokinetic/pharmacodynamic modeling in drug development

Good Practices in Model‐Informed Drug Discovery and Development: Practice, Application, and Documentation

Modelling response time profiles in the absence of drug concentrations: definition and performance evaluation of the K-PD model

Animal Health Modeling & Simulation Society: a new society promoting model-based approaches in veterinary pharmacology

Pharmacometrics: Opportunity for Reducing Disease Burden in the Developing World: The Case of Africa

Modeling and Simulation to Optimize the Design and Analysis of Confirmatory Trials, Characterize Risk–Benefit, and Support Label Claims

Population pharmacokinetics of ibandronate in Caucasian and Japanese healthy males and postmenopausal females

Practical experience and issues in designing and performing population pharmacokinetic/pharmacodynamic studies

Sparse sampling for assessment of drug exposure in toxicological studies

Population approaches in drug development. Report on an expert meeting to discuss population pharmacokinetic/pharmacodynamic software

L’architecture religieuse en Allemagne entre 1220 et 1350

Recherches récentes sur le gothique tardif (1350-1550)

Effect of adrenalectomy and aldosterone on the modulation of mineralocorticoid receptors in rat kidney

La méthode de la clairance rénale pour l'individualisation des posologies du lithium en routine hospitalière

Physiologically based pharmacokinetic study on a cyclosporin derivative, SDZ IMM 125

Cytoplasmic and nuclear uptake of aldosterone in toad bladder: a mathematical modeling approach

Alternative Approaches to Estimation of Population Pharmacokinetic Parameters: Comparison with the Nonlinear Mixed-Effect Model

Application of Sparse Sampling Approaches in Rodent Toxicokinetics: A Prospective View

Clinical pharmacokinetic/pharmacodynamic and physiologically based pharmacokinetic modeling in new drug development: the capecitabine experience

An application of population pharmacokinetics to the clinical use of cyclosporine in bone marrow transplant patients

A Time-Lag Model for Pharmacokinetics of Drugs Subject to Enterohepatic Circulation

Cytoplasmic and nuclear uptake of aldosterone in toad bladder: a mathematical modeling approach

Can compartment models account for nonmonotonicity in pharmacokinetics?

Finite element simulation of gas transport in proximal respiratory airways: Comparison with experimental data

Bioequivalence of dosage forms. The confidence interval approach. Westlake's method (author's transl)

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