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The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type

Cell metabolism, 2012-02, Vol.15 (2), p.157-170

2012

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Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase

Nature communications, 2020-02, Vol.11 (1), p.698-17, Article 698

2020

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Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells

Cell metabolism, 2014-05, Vol.19 (5), p.795-809

2014

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Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells

Cell metabolism, 2012-01, Vol.15 (1), p.110-121

2012

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Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation

The Journal of clinical investigation, 2015-02, Vol.125 (2), p.687-698

2015

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De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues

The Journal of biological chemistry, 2019-09, Vol.294 (36), p.13464-13477

2019

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Acute loss of iron–sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells

The Journal of biological chemistry, 2018-05, Vol.293 (21), p.8297-8311

2018

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Ultrahigh resolution MS1/MS2-based reconstruction of metabolic networks in mammalian cells reveals changes for selenite and arsenite action

The Journal of biological chemistry, 2022-12, Vol.298 (12), p.102586, Article 102586

2022

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Metabolic reprogramming in tumors: Contributions of the tumor microenvironment

Genes & diseases, 2020-06, Vol.7 (2), p.185-198

2020

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6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function

eLife, 2021-10, Vol.10

2021

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Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype

The Journal of immunology (1950), 2015-11, Vol.195 (10), p.5055-5065

2015

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An obligatory role for neurotensin in high-fat-diet-induced obesity

Nature (London), 2016-05, Vol.533 (7603), p.411-415

2016

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Metabolic Reprogramming in Human Cancer Patients and Patient-Derived Models

Cold Spring Harbor perspectives in medicine, 2024-07, p.a041552

2024

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Myeloid-derived suppressor cell mitochondrial fitness governs chemotherapeutic efficacy in hematologic malignancies

Nature communications, 2024-03, Vol.15 (1), p.2803-19, Article 2803

2024

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Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function

Cell reports (Cambridge), 2021-03, Vol.34 (10), p.108831-108831, Article 108831

2021

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Metabolic reprogramming driven by EZH2 inhibition depends on cell-matrix interactions

The Journal of biological chemistry, 2024-01, Vol.300 (1), p.105485-105485, Article 105485

2024

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Stable isotope-resolved metabolomics and applications for drug development

Pharmacology & therapeutics (Oxford), 2012-03, Vol.133 (3), p.366-391

2012

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Applications of chromatography-ultra high-resolution MS for stable isotope-resolved metabolomics (SIRM) reconstruction of metabolic networks

TrAC, Trends in analytical chemistry (Regular ed.), 2020-02, Vol.123, p.115676, Article 115676

2020

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Probing the metabolic phenotype of breast cancer cells by multiple tracer stable isotope resolved metabolomics

Metabolic engineering, 2017-09, Vol.43 (Pt B), p.125-136

2017

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Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling

Scientific reports, 2014-06, Vol.4 (1), p.5414-5414, Article 5414

2014

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An Ion Chromatography-Ultrahigh-Resolution-MS 1 /Data-Independent High-Resolution MS 2 Method for Stable Isotope-Resolved Metabolomics Reconstruction of Central Metabolic Networks

Analytical chemistry (Washington), 2021-02, Vol.93 (5), p.2749-2757

2021

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Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes

The Journal of biological chemistry, 2023-12, Vol.299 (12), p.105407, Article 105407

2023

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Innate immune activation by checkpoint inhibition in human patient-derived lung cancer tissues

eLife, 2021-08, Vol.10

2021

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Metabolic reprogramming and Notch activity distinguish between non-small cell lung cancer subtypes

British journal of cancer, 2019-07, Vol.121 (1), p.51-64

2019

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Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues

The Journal of immunology (1950), 2022-11, Vol.209 (9), p.1674-1690

2022

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The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type

Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase

Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells

Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation

De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues

Acute loss of iron–sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells

Ultrahigh resolution MS1/MS2-based reconstruction of metabolic networks in mammalian cells reveals changes for selenite and arsenite action

Metabolic reprogramming in tumors: Contributions of the tumor microenvironment

6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function

Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype

An obligatory role for neurotensin in high-fat-diet-induced obesity

Metabolic Reprogramming in Human Cancer Patients and Patient-Derived Models

Myeloid-derived suppressor cell mitochondrial fitness governs chemotherapeutic efficacy in hematologic malignancies

Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function

Metabolic reprogramming driven by EZH2 inhibition depends on cell-matrix interactions

Stable isotope-resolved metabolomics and applications for drug development

Applications of chromatography-ultra high-resolution MS for stable isotope-resolved metabolomics (SIRM) reconstruction of metabolic networks

Probing the metabolic phenotype of breast cancer cells by multiple tracer stable isotope resolved metabolomics

Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling

An Ion Chromatography-Ultrahigh-Resolution-MS 1 /Data-Independent High-Resolution MS 2 Method for Stable Isotope-Resolved Metabolomics Reconstruction of Central Metabolic Networks

Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes

Innate immune activation by checkpoint inhibition in human patient-derived lung cancer tissues

Metabolic reprogramming and Notch activity distinguish between non-small cell lung cancer subtypes

Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues

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