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Structure and Interactions of the Human Programmed Cell Death 1 Receptor

The Journal of biological chemistry, 2013-04, Vol.288 (17), p.11771-11785

2013

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PD‐1/PD‐L1 immune checkpoint: Potential target for cancer therapy

Journal of cellular physiology, 2019-02, Vol.234 (2), p.1313-1325

2019

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PD‐1/PD‐L1‐dependent immune response in colorectal cancer

Journal of cellular physiology, 2020-07, Vol.235 (7-8), p.5461-5475

2020

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Evolving insights into the mechanisms of toxicity associated with immune checkpoint inhibitor therapy

British journal of clinical pharmacology, 2020-09, Vol.86 (9), p.1778-1789

2020

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The PD-1/PD-Ls pathway and autoimmune diseases

Cellular immunology, 2014-07, Vol.290 (1), p.72-79

2014

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Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy

Clinical cancer research, 2014-10, Vol.20 (19), p.5064-5074

2014

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Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2

Structure (London), 2017-08, Vol.25 (8), p.1163-1174

2017

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A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery

Proceedings of the National Academy of Sciences - PNAS, 2019-12, Vol.116 (49), p.24500-24506

2019

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Cellular and molecular regulation of the programmed death-1/programmed death ligand system and its role in multiple sclerosis and other autoimmune diseases

Journal of autoimmunity, 2021-09, Vol.123, p.102702-102702, Article 102702

2021

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TIGIT and PD-1 impair tumor antigen-specific CD8⁺ T cells in melanoma patients

The Journal of clinical investigation, 2015-05, Vol.125 (5), p.2046-2058

2015

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A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

Nature immunology, 2013-12, Vol.14 (12), p.1212-1218

2013

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The structural features that distinguish PD-L2 from PD-L1 emerged in placental mammals

The Journal of biological chemistry, 2020-04, Vol.295 (14), p.4372-4380

2020

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Immune Checkpoint Inhibitors in Non‐Small Cell Lung Cancer

The oncologist (Dayton, Ohio), 2017-01, Vol.22 (1), p.81-88

2017

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Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

Blood, 2013-10, Vol.122 (17), p.3062-3073

2013

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Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation

Cancer cell, 2018-03, Vol.33 (3), p.480-494.e7

2018

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Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Cancer cell, 2022-02, Vol.40 (2), p.201-218.e9

2022

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Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR Mutation

Journal of thoracic oncology, 2015-06, Vol.10 (6), p.910-923

2015

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Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

Cancer cell, 2015-04, Vol.27 (4), p.450-461

2015

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Multiplex Genome Editing to Generate Universal CAR T Cells Resistant to PD1 Inhibition

Clinical cancer research, 2017-05, Vol.23 (9), p.2255-2266

2017

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Mechanical force regulates ligand binding and function of PD-1

Nature communications, 2024-09, Vol.15 (1), p.8339-15, Article 8339

2024

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Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (5), p.E761-E770

2017

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Subsets of exhausted CD8 + T cells differentially mediate tumor control and respond to checkpoint blockade

Nature immunology, 2019-03, Vol.20 (3), p.326-336

2019

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The Role of PD-1 in Acute and Chronic Infection

Frontiers in immunology, 2020-03, Vol.11, p.487-487

2020

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Structure and Interactions of the Human Programmed Cell Death 1 Receptor

PD‐1/PD‐L1 immune checkpoint: Potential target for cancer therapy

PD‐1/PD‐L1‐dependent immune response in colorectal cancer

Evolving insights into the mechanisms of toxicity associated with immune checkpoint inhibitor therapy

The PD-1/PD-Ls pathway and autoimmune diseases

Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy

Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2

A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery

Cellular and molecular regulation of the programmed death-1/programmed death ligand system and its role in multiple sclerosis and other autoimmune diseases

Major Histocompatibility Complex Class II and Programmed Death Ligand 1 Expression Predict Outcome After Programmed Death 1 Blockade in Classic Hodgkin Lymphoma

TIGIT and PD-1 impair tumor antigen-specific CD8⁺ T cells in melanoma patients

A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

The structural features that distinguish PD-L2 from PD-L1 emerged in placental mammals

Immune Checkpoint Inhibitors in Non‐Small Cell Lung Cancer

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR Mutation

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

Multiplex Genome Editing to Generate Universal CAR T Cells Resistant to PD1 Inhibition

Mechanical force regulates ligand binding and function of PD-1

Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity

Subsets of exhausted CD8 + T cells differentially mediate tumor control and respond to checkpoint blockade

The Role of PD-1 in Acute and Chronic Infection

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