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Precision Medicine in Cancer Therapy

1, 2019

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Tumor-Treating Fields: A Fourth Modality in Cancer Treatment

Clinical cancer research, 2018-01, Vol.24 (2), p.266-275

2018

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Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

Cancer cell, 2012-03, Vol.21 (3), p.418-429

2012

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Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells

PloS one, 2016-10, Vol.11 (10), p.e0165586-e0165586

2016

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Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer

PloS one, 2017-08, Vol.12 (8), p.e0183871-e0183871

2017

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Neratinib degrades MST4 via autophagy that reduces membrane stiffness and is essential for the inactivation of PI3K, ERK1/2, and YAP/TAZ signaling

Journal of cellular physiology, 2020-11, Vol.235 (11), p.7889-7899

2020

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Tumor-stroma interactions in pancreatic ductal adenocarcinoma

Molecular cancer therapeutics, 2007-04, Vol.6 (4), p.1186-1197

2007

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Perineural invasion and associated pain in pancreatic cancer

Nature reviews. Cancer, 2011-10, Vol.11 (10), p.695

2011

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Pancreatic acinar cell carcinoma: A review on molecular profiling of patient tumors

World journal of gastroenterology : WJG, 2017-12, Vol.23 (45), p.7945-7951

2017

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Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look

Cancer discovery, 2011-09, Vol.1 (4), p.291-296

2011

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Down-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells

PloS one, 2012-03, Vol.7 (3), p.e32783

2012

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Translational Therapeutic Opportunities in Ductal Adenocarcinoma of the Pancreas

Clinical cancer research, 2012-08, Vol.18 (16), p.4249-4256

2012

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Pancreatic Cancer: "A Riddle Wrapped in a Mystery inside an Enigma"

Clinical cancer research, 2017-04, Vol.23 (7), p.1629-1637

2017

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Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions

Genome medicine, 2020-09, Vol.12 (1), p.80-80, Article 80

2020

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Identification of somatic mutations in cancer through Bayesian-based analysis of sequenced genome pairs

BMC genomics, 2013-05, Vol.14 (1), p.302-302, Article 302

2013

Volltextzugriff (PDF)

Inhibiting stromal Class I HDACs curbs pancreatic cancer progression

Nature communications, 2023-12, Vol.14 (1), p.7791-7791, Article 7791

2023

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Extracellular Vesicles in Diagnosis and Treatment of Pancreatic Cancer: Current State and Future Perspectives

Cancers, 2020-06, Vol.12 (6), p.1530

2020

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Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression

Clinical cancer research, 2018-10, Vol.24 (19), p.4798-4807

2018

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Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts

Oncogenesis (New York, NY), 2020-11, Vol.9 (11), p.100-100, Article 100

2020

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Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas

Cancer research (Chicago, Ill.), 2020-10, Vol.80 (20), p.4324-4334

2020

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Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer

PloS one, 2017-02, Vol.12 (2), p.e0171827

2017

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Phase Ib Trial of the PI3K Inhibitor Copanlisib Combined with the Allosteric MEK Inhibitor Refametinib in Patients with Advanced Cancer

Targeted oncology, 2020-04, Vol.15 (2), p.163-174

2020

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Analysis of recurrently protected genomic regions in cell-free DNA found in urine

Science translational medicine, 2021-02, Vol.13 (581)

2021

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Increasing Stress to Induce Apoptosis in Pancreatic Cancer via the Unfolded Protein Response (UPR)

International journal of molecular sciences, 2022-12, Vol.24 (1), p.577

2022

Volltextzugriff (PDF)

Phase II clinical trial of nab‐paclitaxel plus cisplatin plus gemcitabine (NABPLAGEM) in patients with untreated advanced pancreatic cancer

Cancer medicine (Malden, MA), 2024-06, Vol.13 (12), p.n/a

2024

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Precision Medicine in Cancer Therapy

Tumor-Treating Fields: A Fourth Modality in Cancer Treatment

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells

Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer

Neratinib degrades MST4 via autophagy that reduces membrane stiffness and is essential for the inactivation of PI3K, ERK1/2, and YAP/TAZ signaling

Tumor-stroma interactions in pancreatic ductal adenocarcinoma

Perineural invasion and associated pain in pancreatic cancer

Pancreatic acinar cell carcinoma: A review on molecular profiling of patient tumors

Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look

Down-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells

Translational Therapeutic Opportunities in Ductal Adenocarcinoma of the Pancreas

Pancreatic Cancer: "A Riddle Wrapped in a Mystery inside an Enigma"

Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions

Identification of somatic mutations in cancer through Bayesian-based analysis of sequenced genome pairs

Inhibiting stromal Class I HDACs curbs pancreatic cancer progression

Extracellular Vesicles in Diagnosis and Treatment of Pancreatic Cancer: Current State and Future Perspectives

Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression

Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts

Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas

Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer

Phase Ib Trial of the PI3K Inhibitor Copanlisib Combined with the Allosteric MEK Inhibitor Refametinib in Patients with Advanced Cancer

Analysis of recurrently protected genomic regions in cell-free DNA found in urine

Increasing Stress to Induce Apoptosis in Pancreatic Cancer via the Unfolded Protein Response (UPR)

Phase II clinical trial of nab‐paclitaxel plus cisplatin plus gemcitabine (NABPLAGEM) in patients with untreated advanced pancreatic cancer

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