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Current approaches for ADME characterization of antibody-drug conjugates: An industry white paper

Drug metabolism and pharmacokinetics, 2017-01, Vol.32 (1), p.S5-S5

Tarcsa, Edit

2017

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Citrullination: A posttranslational modification in health and disease

The international journal of biochemistry & cell biology, 2006, Vol.38 (10), p.1662-1677

2006

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Elezanumab, a clinical stage human monoclonal antibody that selectively targets repulsive guidance molecule A to promote neuroregeneration and neuroprotection in neuronal injury and demyelination models

Neurobiology of disease, 2021-11, Vol.159, p.105492, Article 105492

2021

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Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin

Nature biotechnology, 2007-11, Vol.25 (11), p.1290-1297

2007

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Immunogenicity assessment of AAV-based gene therapies: An IQ consortium industry white paper

Molecular therapy. Methods & clinical development, 2022-09, Vol.26, p.471-494

2022

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ADME of biologics

Drug metabolism and pharmacokinetics, 2017-01, Vol.32 (1), p.S1-S1

Tarcsa, Edit

2017

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Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig

Protein & cell, 2018-01, Vol.9 (1), p.121-129

2018

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Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper

Drug metabolism and disposition, 2016-05, Vol.44 (5), p.617-623

2016

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Biochemical, Structural, and Transglutaminase Substrate Properties Of Human Loricrin, the Major Epidermal Cornified Cell Envelope Protein (∗)

The Journal of biological chemistry, 1995-11, Vol.270 (44), p.26382-26390

1995

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An IQ Consortium Perspective on Best Practices for Bioanalytical and Immunogenicity Assessment Aspects of CAR‐T and TCR‐T Cellular Therapies Development

Clinical pharmacology and therapeutics, 2024-02, Vol.115 (2), p.188-200

2024

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Quantitation of a recombinant monoclonal antibody in monkey serum by liquid chromatography–mass spectrometry

Analytical biochemistry, 2011-07, Vol.414 (1), p.147-153

2011

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Antibody-drug conjugates as targeted therapies: Are we there yet? A critical review of the current clinical landscape

Drug discovery today. Technologies, 2020-12, Vol.37, p.13-22

2020

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Preexisting antibody assays for gene therapy: Considerations on patient selection cutoffs and companion diagnostic requirements

Molecular therapy. Methods & clinical development, 2024-03, Vol.32 (1), p.101217-101217, Article 101217

2024

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Structural and Transglutaminase Substrate Properties of the Small Proline-rich 2 Family of Cornified Cell Envelope Proteins

The Journal of biological chemistry, 1998-09, Vol.273 (36), p.23297-23303

1998

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Non-clinical Safety Evaluation of Biotherapeutics – Challenges, Opportunities and new Insights

Regulatory toxicology and pharmacology, 2016-10, Vol.80, p.S1-S14

2016

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Transglutaminase crosslinking and structural studies of the human small proline rich 3 protein

Cell death and differentiation, 1999-09, Vol.6 (9), p.916-930

1999

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Generation and characterization of ABT-981, a dual variable domain immunoglobulin (DVD-IgTM) molecule that specifically and potently neutralizes both IL-1α and IL-1β

mAbs, 2015-05, Vol.7 (3), p.605-619

2015

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The Bcl-2 Family Antagonist ABT-737 Significantly Inhibits Multiple Animal Models of Autoimmunity

The Journal of immunology (1950), 2009-06, Vol.182 (12), p.7482-7489

2009

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Ca2+-free Calmodulin and Calmodulin Damaged byin Vitro Aging Are Selectively Degraded by 26 S Proteasomes without Ubiquitination

The Journal of biological chemistry, 2000-07, Vol.275 (27), p.20295-20301

2000

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The unfolding of substrates and ubiquitin-independentprotein degradation by proteasomes

Biochimie, 2001-03, Vol.83 (3), p.311-318

2001

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Protein unfolding by peptidylarginine deiminase. Substrate specificity and structural relationships of the natural substrates trichohyalin and filaggrin

The Journal of biological chemistry, 1996-11, Vol.271 (48), p.30709-30716

1996

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Transglutaminase Cross-linking Properties of the Small Proline-rich 1 Family of Cornified Cell Envelope Proteins

The Journal of biological chemistry, 1999-03, Vol.274 (11), p.7226-7237

1999

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The Fate of Trichohyalin

The Journal of biological chemistry, 1997-10, Vol.272 (44), p.27893-27901

1997

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The fate of trichohyalin. Sequential post-translational modifications by peptidyl-arginine deiminase and transglutaminases

The Journal of biological chemistry, 1997-10, Vol.272 (44), p.27893-27901

1997

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Protein Unfolding by Peptidylarginine Deiminase

The Journal of biological chemistry, 1996-11, Vol.271 (48), p.30709-30716

1996

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Current approaches for ADME characterization of antibody-drug conjugates: An industry white paper

Citrullination: A posttranslational modification in health and disease

Elezanumab, a clinical stage human monoclonal antibody that selectively targets repulsive guidance molecule A to promote neuroregeneration and neuroprotection in neuronal injury and demyelination models

Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin

Immunogenicity assessment of AAV-based gene therapies: An IQ consortium industry white paper

ADME of biologics

Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig

Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper

Biochemical, Structural, and Transglutaminase Substrate Properties Of Human Loricrin, the Major Epidermal Cornified Cell Envelope Protein (∗)

An IQ Consortium Perspective on Best Practices for Bioanalytical and Immunogenicity Assessment Aspects of CAR‐T and TCR‐T Cellular Therapies Development

Quantitation of a recombinant monoclonal antibody in monkey serum by liquid chromatography–mass spectrometry

Antibody-drug conjugates as targeted therapies: Are we there yet? A critical review of the current clinical landscape

Preexisting antibody assays for gene therapy: Considerations on patient selection cutoffs and companion diagnostic requirements

Structural and Transglutaminase Substrate Properties of the Small Proline-rich 2 Family of Cornified Cell Envelope Proteins

Non-clinical Safety Evaluation of Biotherapeutics – Challenges, Opportunities and new Insights

Transglutaminase crosslinking and structural studies of the human small proline rich 3 protein

Generation and characterization of ABT-981, a dual variable domain immunoglobulin (DVD-IgTM) molecule that specifically and potently neutralizes both IL-1α and IL-1β

The Bcl-2 Family Antagonist ABT-737 Significantly Inhibits Multiple Animal Models of Autoimmunity

Ca2+-free Calmodulin and Calmodulin Damaged byin Vitro Aging Are Selectively Degraded by 26 S Proteasomes without Ubiquitination

The unfolding of substrates and ubiquitin-independentprotein degradation by proteasomes

Protein unfolding by peptidylarginine deiminase. Substrate specificity and structural relationships of the natural substrates trichohyalin and filaggrin

Transglutaminase Cross-linking Properties of the Small Proline-rich 1 Family of Cornified Cell Envelope Proteins

The Fate of Trichohyalin

The fate of trichohyalin. Sequential post-translational modifications by peptidyl-arginine deiminase and transglutaminases

Protein Unfolding by Peptidylarginine Deiminase

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