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Mechanisms of action of isoniazid

Molecular microbiology, 2006-12, Vol.62 (5), p.1220-1227

2006

Volltextzugriff (PDF)

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (46), p.E3168-E3176

2012

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Ambroxol Induces Autophagy and Potentiates Rifampin Antimycobacterial Activity

Antimicrobial agents and chemotherapy, 2018-09, Vol.62 (9)

2018

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Deuterated drugs: where are we now?

Expert opinion on therapeutic patents, 2014-10, Vol.24 (10), p.1067-1075

Timmins, Graham S

2014

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Rapamycin modulates pulmonary pathology in a murine model of Mycobacterium tuberculosis infection

Disease models & mechanisms, 2021-10, Vol.14 (10)

2021

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Deuterated drugs; updates and obviousness analysis

Expert opinion on therapeutic patents, 2017-12, Vol.27 (12), p.1353-1361

Timmins, Graham S.

2017

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Evidence-based obviousness for use in patent prosecution and review

Nature biotechnology, 2019-09, Vol.37 (9), p.997-1000

Timmins, Graham S

2019

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Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity

Toxicology and applied pharmacology, 2008-10, Vol.232 (1), p.41-50

2008

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UV Causation of Melanoma in Xiphophorus Is Dominated by Melanin Photosensitized Oxidant Production

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (11), p.4111-4115

2006

Volltextzugriff (PDF)

What are the challenges in commercial non-tuberculous mycobacteria (NTM) drug discovery and how should we move forward?

Expert opinion on drug discovery, 2020-01, Vol.15 (1), p.7-9

Timmins, Graham S

2020

Volltextzugriff (PDF)

Enhancement of lung levels of antibiotics by ambroxol and bromhexine

Expert opinion on drug metabolism & toxicology, 2019-03, Vol.15 (3), p.213-218

2019

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Rapid in vivo detection of isoniazid-sensitive Mycobacterium tuberculosis by breath test

Nature communications, 2014-09, Vol.5 (1), p.4989-4989, Article 4989

2014

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Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential

Nature communications, 2015-10, Vol.6 (1), p.8620-8620, Article 8620

2015

Volltextzugriff (PDF)

Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes

Cell, 2021-11, Vol.184 (24), p.5950-5969.e22

2021

Volltextzugriff (PDF)

Nitric Oxide Generated from Isoniazid Activation by KatG: Source of Nitric Oxide and Activity against Mycobacterium tuberculosis

Antimicrobial Agents and Chemotherapy, 2004-08, Vol.48 (8), p.3006-3009

2004

Volltextzugriff (PDF)

Mycobacteria Inhibit Nitric Oxide Synthase Recruitment to Phagosomes during Macrophage Infection

Infection and Immunity, 2004-05, Vol.72 (5), p.2872-2878

2004

Volltextzugriff (PDF)

Stable isotope biomarker breath tests for human metabolic and infectious diseases: a review of recent patent literature

Expert opinion on therapeutic patents, 2016-12, Vol.26 (12), p.1393-1398

Timmins, Graham S.

2016

Volltextzugriff (PDF)

Mammalian hybrid prophagophore is a precursor to autophagosomes

Autophagy, 2023-08, Vol.19 (8), p.2391-2392

2023

Volltextzugriff (PDF)

Inactivation of a Bacterial Virulence Pheromone by Phagocyte-Derived Oxidants: New Role for the NADPH Oxidase in Host Defense

Proceedings of the National Academy of Sciences - PNAS, 2004-09, Vol.101 (38), p.13867-13872

2004

Volltextzugriff (PDF)

Detecting virulence and drug-resistance mycobacterial phenotypes in vivo

Trends in microbiology (Regular ed.), 2015-06, Vol.23 (6), p.321-323

Timmins, Graham S

2015

Volltextzugriff (PDF)

Mycobacterium tuberculosis prevents inflammasome activation

Cell host & microbe, 2008-04, Vol.3 (4), p.224-232

2008

Volltextzugriff (PDF)

Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria

Nature chemical biology, 2010-01, Vol.6 (1), p.41

2010

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Direct visualization of mouse brain oxygen distribution by electron paramagnetic resonance imaging: application to focal cerebral ischemia

Journal of cerebral blood flow and metabolism, 2009-10, Vol.29 (10), p.1695-1703

2009

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Microarray Analysis and Functional Characterization of the Nitrosative Stress Response in Nonmucoid and Mucoid Pseudomonas aeruginosa

Journal of Bacteriology, 2004-06, Vol.186 (12), p.4046-4050

2004

Volltextzugriff (PDF)

Neuronal Zinc Transporter ZnT3 Modulates Cerebral Ischemia-Induced Blood-Brain Barrier Disruption

Aging and disease, 2023-10

2023

Volltextzugriff (PDF)

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Mechanisms of action of isoniazid

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

Ambroxol Induces Autophagy and Potentiates Rifampin Antimycobacterial Activity

Deuterated drugs: where are we now?

Rapamycin modulates pulmonary pathology in a murine model of Mycobacterium tuberculosis infection

Deuterated drugs; updates and obviousness analysis

Evidence-based obviousness for use in patent prosecution and review

Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity

UV Causation of Melanoma in Xiphophorus Is Dominated by Melanin Photosensitized Oxidant Production

What are the challenges in commercial non-tuberculous mycobacteria (NTM) drug discovery and how should we move forward?

Enhancement of lung levels of antibiotics by ambroxol and bromhexine

Rapid in vivo detection of isoniazid-sensitive Mycobacterium tuberculosis by breath test

Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential

Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes

Nitric Oxide Generated from Isoniazid Activation by KatG: Source of Nitric Oxide and Activity against Mycobacterium tuberculosis

Mycobacteria Inhibit Nitric Oxide Synthase Recruitment to Phagosomes during Macrophage Infection

Stable isotope biomarker breath tests for human metabolic and infectious diseases: a review of recent patent literature

Mammalian hybrid prophagophore is a precursor to autophagosomes

Inactivation of a Bacterial Virulence Pheromone by Phagocyte-Derived Oxidants: New Role for the NADPH Oxidase in Host Defense

Detecting virulence and drug-resistance mycobacterial phenotypes in vivo

Mycobacterium tuberculosis prevents inflammasome activation

Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria

Direct visualization of mouse brain oxygen distribution by electron paramagnetic resonance imaging: application to focal cerebral ischemia

Microarray Analysis and Functional Characterization of the Nitrosative Stress Response in Nonmucoid and Mucoid Pseudomonas aeruginosa

Neuronal Zinc Transporter ZnT3 Modulates Cerebral Ischemia-Induced Blood-Brain Barrier Disruption

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