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Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients

Food and chemical toxicology, 2007-12, Vol.45 (12), p.2533-2562

2007

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The Threshold of Toxicological Concern (TTC) in risk assessment

Toxicology letters, 2008-08, Vol.180 (2), p.151-156

2008

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Structure-based thresholds of toxicological concern (TTC): guidance for application to substances present at low levels in the diet

Food and chemical toxicology, 2004, Vol.42 (1), p.65-83

2004

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Evaluation of the Threshold of Toxicological Concern (TTC) – Challenges and approaches

Regulatory toxicology and pharmacology, 2013-02, Vol.65 (1), p.168-177

2013

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Microbial hydrolysis of steviol glycosides

Food and chemical toxicology, 2008-07, Vol.46 (7), p.S70-S74

2008

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The use of a sweetener substitution method to predict dietary exposures for the intense sweetener rebaudioside A

Food and chemical toxicology, 2008-07, Vol.46 (7), p.S61-S69

Renwick, A.G.

2008

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Approaches to the risk assessment of genotoxic carcinogens in food: A critical appraisal

Food and chemical toxicology, 2006-10, Vol.44 (10), p.1613-1635

2006

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First European conference on aspartame: Putting safety and benefits into perspective. Synopsis of presentations and conclusions

Food and chemical toxicology, 2007-07, Vol.45 (7), p.1308-1313

2007

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Risk–benefit analysis of micronutrients

Food and chemical toxicology, 2004-12, Vol.42 (12), p.1903-1922

2004

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Human Variability and Noncancer Risk Assessment— An Analysis of the Default Uncertainty Factor

Regulatory toxicology and pharmacology, 1998-02, Vol.27 (1), p.3-20

1998

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Human variability in the renal elimination of foreign compounds and renal excretion-related uncertainty factors for risk assessment

Food and chemical toxicology, 2004-02, Vol.42 (2), p.275-298

2004

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Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?

Food and chemical toxicology, 2002-11, Vol.40 (11), p.1633-1656

2002

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Uncertainty factors for chemical risk assessment: interspecies differences in the in vivo pharmacokinetics and metabolism of human CYP1A2 substrates

Food and chemical toxicology, 2001-07, Vol.39 (7), p.667-680

2001

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An Analysis of the Possibility for Health Implications of Joint Actions and Interactions between Food Additives

Regulatory toxicology and pharmacology, 2000-02, Vol.31 (1), p.77-91

2000

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Postscript on advantame – A novel high-potency low-calorie sweetener

Food and chemical toxicology, 2011-11, Vol.49, p.S1-S1

Renwick, A.G.

2011

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Risk assessment of dietary exposures to compounds that are genotoxic and carcinogenic—An overview

Toxicology letters, 2008-08, Vol.180 (2), p.110-117

2008

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Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review

Food and chemical toxicology, 2005-02, Vol.43 (2), p.203-216

2005

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The effect of aspartame metabolites on the suckling rat frontal cortex acetylcholinesterase. An in vitro study. By I. Simintzi, K.H. Schulpis, P. Angelogianni, C. Liapi and S. Tsakiris

Food and chemical toxicology, 2008-03, Vol.46 (3), p.1206-1207

Renwick, A.G.

2008

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Guidance for the safety assessment of botanicals and botanical preparations for use in food and food supplements

Food and chemical toxicology, 2003-12, Vol.41 (12), p.1625-1649

2003

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Hazard characterisation of chemicals in food and diet: dose response, mechanisms and extrapolation issues

Food and chemical toxicology, 2002-02, Vol.40 (2), p.237-282

2002

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Uncertainty factors for chemical risk assessment

Food and chemical toxicology, 2001-07, Vol.39 (7), p.681-696

2001

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Risk characterisation of chemicals in food and diet

Food and chemical toxicology, 2003-09, Vol.41 (9), p.1211-1271

2003

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47 Risk characterization

Toxicology letters, 2003-09, Vol.144, p.s15-s15

Renwick, A.G.

2003

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52 Toxicology databases and the toxicity threshold concept used by JECFA

Toxicology letters, 2003-09, Vol.144, p.s17-s17

Renwick, A.G.

2003

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Structure-based thresholds of toxicological concern—guidance for application to substances present at low levels in the diet

Toxicology and applied pharmacology, 2005-09, Vol.207 (2), p.585-591

Renwick, A.G.

2005

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Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients

The Threshold of Toxicological Concern (TTC) in risk assessment

Structure-based thresholds of toxicological concern (TTC): guidance for application to substances present at low levels in the diet

Evaluation of the Threshold of Toxicological Concern (TTC) – Challenges and approaches

Microbial hydrolysis of steviol glycosides

The use of a sweetener substitution method to predict dietary exposures for the intense sweetener rebaudioside A

Approaches to the risk assessment of genotoxic carcinogens in food: A critical appraisal

First European conference on aspartame: Putting safety and benefits into perspective. Synopsis of presentations and conclusions

Risk–benefit analysis of micronutrients

Human Variability and Noncancer Risk Assessment— An Analysis of the Default Uncertainty Factor

Human variability in the renal elimination of foreign compounds and renal excretion-related uncertainty factors for risk assessment

Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?

Uncertainty factors for chemical risk assessment: interspecies differences in the in vivo pharmacokinetics and metabolism of human CYP1A2 substrates

An Analysis of the Possibility for Health Implications of Joint Actions and Interactions between Food Additives

Postscript on advantame – A novel high-potency low-calorie sweetener

Risk assessment of dietary exposures to compounds that are genotoxic and carcinogenic—An overview

Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review

The effect of aspartame metabolites on the suckling rat frontal cortex acetylcholinesterase. An in vitro study. By I. Simintzi, K.H. Schulpis, P. Angelogianni, C. Liapi and S. Tsakiris

Guidance for the safety assessment of botanicals and botanical preparations for use in food and food supplements

Hazard characterisation of chemicals in food and diet: dose response, mechanisms and extrapolation issues

Uncertainty factors for chemical risk assessment

Risk characterisation of chemicals in food and diet

47 Risk characterization

52 Toxicology databases and the toxicity threshold concept used by JECFA

Structure-based thresholds of toxicological concern—guidance for application to substances present at low levels in the diet

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