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Skeletal health in DYRK1A syndrome

Frontiers in neuroscience, 2024-09, Vol.18, p.1462893

2024

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Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model

Neurobiology of disease, 2024-01, Vol.190, p.106359-106359, Article 106359

2024

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Defective Cerebellar Response to Mitogenic Hedgehog Signaling in Down's Syndrome Mice

Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (5), p.1452-1456

2006

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Targeting trisomic treatments: optimizing Dyrk1a inhibition to improve Down syndrome deficits

Molecular genetics & genomic medicine, 2017-09, Vol.5 (5), p.451-465

2017

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Compromised femoral and lumbovertebral bone in the Dp(16)1Yey Down syndrome mouse model

Bone (New York, N.Y.), 2024-04, Vol.181, p.117046-117046, Article 117046

2024

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Skeletal dynamics of Down syndrome: A developing perspective

Bone (New York, N.Y.), 2020-04, Vol.133, p.115215-115215, Article 115215

2020

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A new Down syndrome rat model races forward

Trends in genetics, 2022-11, Vol.38 (11), p.1101-1102

2022

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Evaluation of the therapeutic potential of Epigallocatechin-3-gallate (EGCG) via oral gavage in young adult Down syndrome mice

Scientific reports, 2020-06, Vol.10 (1), p.10426-10426, Article 10426

2020

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Influence of allelic differences in Down syndrome

Progress in brain research, 2020-01, Vol.251, p.29-54

2020

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Understanding the basis for Down syndrome phenotypes

PLoS genetics, 2006-03, Vol.2 (3), p.e50-e50

2006

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Current Analysis of Skeletal Phenotypes in Down Syndrome

Current osteoporosis reports, 2021-06, Vol.19 (3), p.338-346

2021

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Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome

Bone (New York, N.Y.), 2020-07, Vol.136, p.115367-115367, Article 115367

2020

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Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome

Human molecular genetics, 2016-11, Vol.25 (22), p.4856-4869

2016

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Low dose EGCG treatment beginning in adolescence does not improve cognitive impairment in a Down syndrome mouse model

Pharmacology, biochemistry and behavior, 2015-11, Vol.138, p.70-79

2015

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Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome

Nature communications, 2022-10, Vol.13 (1), p.6384-17, Article 6384

2022

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Trisomic and allelic differences influence phenotypic variability during development of Down syndrome mice

Genetics (Austin), 2011-12, Vol.189 (4), p.1487-1495

2011

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Behavioral Phenotyping for Down Syndrome in Mice

Current protocols in mouse biology, 2020-09, Vol.10 (3), p.e79-n/a

2020

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Trying Out Genes for Size: Experiential Learning in the High School Classroom

The American biology teacher, 2013-11, Vol.75 (9)

2013

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Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice

Bone (New York, N.Y.), 2011-02, Vol.48 (2), p.275-280

2011

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Commonality in Down and fetal alcohol syndromes

Birth defects research. A Clinical and molecular teratology, 2013-04, Vol.97 (4), p.187-197

2013

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power of comparative and developmental studies for mouse models of Down syndrome

Mammalian genome, 2007-07, Vol.18 (6-7), p.431-443

2007

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Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner

Mechanisms of development, 2015-05, Vol.136, p.133-142

2015

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Embryonic and not maternal trisomy causes developmental attenuation in the Ts65Dn mouse model for Down syndrome

Developmental dynamics, 2010-06, Vol.239 (6), p.1645-1653

2010

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Role of Osteopontin in Murine Lyme Arthritis and Host Defense against Borrelia burgdorferi

Infection and Immunity, 2002-03, Vol.70 (3), p.1372-1381

2002

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Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome

American journal of medical genetics. Part A, 2013-08, Vol.161A (8), p.1866-1874

2013

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Skeletal health in DYRK1A syndrome

Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model

Defective Cerebellar Response to Mitogenic Hedgehog Signaling in Down's Syndrome Mice

Targeting trisomic treatments: optimizing Dyrk1a inhibition to improve Down syndrome deficits

Compromised femoral and lumbovertebral bone in the Dp(16)1Yey Down syndrome mouse model

Skeletal dynamics of Down syndrome: A developing perspective

A new Down syndrome rat model races forward

Evaluation of the therapeutic potential of Epigallocatechin-3-gallate (EGCG) via oral gavage in young adult Down syndrome mice

Influence of allelic differences in Down syndrome

Understanding the basis for Down syndrome phenotypes

Current Analysis of Skeletal Phenotypes in Down Syndrome

Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome

Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome

Low dose EGCG treatment beginning in adolescence does not improve cognitive impairment in a Down syndrome mouse model

Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome

Trisomic and allelic differences influence phenotypic variability during development of Down syndrome mice

Behavioral Phenotyping for Down Syndrome in Mice

Trying Out Genes for Size: Experiential Learning in the High School Classroom

Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice

Commonality in Down and fetal alcohol syndromes

power of comparative and developmental studies for mouse models of Down syndrome

Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner

Embryonic and not maternal trisomy causes developmental attenuation in the Ts65Dn mouse model for Down syndrome

Role of Osteopontin in Murine Lyme Arthritis and Host Defense against Borrelia burgdorferi

Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome

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