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A novel screening test to predict the developmental toxicity of drugs using human induced pluripotent stem cells

The Journal of Toxicological Sciences, 2020, Vol.45(4), pp.187-199

Aikawa, Nobuo

2020

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A Simple Protocol for the Myocardial Differentiation of Human iPS Cells

Biological and Pharmaceutical Bulletin, 2015/07/01, Vol.38(7), pp.1070-1075

2015

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Predicting clinical cardiotoxicity caused by trastuzumab and E-8010 using human cardiomyocytes

Fundamental toxicological sciences, 2017, Vol.4 (4), p.167-171

Aikawa, Nobuo

2017

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The utility of human iPS cell-derived cardiomyocytes in predicting the clinical risk of drugs that display discordance of cardiotoxicity by species

Fundamental toxicological sciences, 2017, Vol.4 (3), p.127-136

Aikawa, Nobuo

2017

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Detection of Thalidomide Embryotoxicity by In Vitro Embryotoxicity Testing Based on Human iPS Cells

Journal of Pharmacological Sciences, 2014/02/20, Vol.124(2), pp.201-207

2014

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Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Fecal Pellet Output Induced by Hyperpropulsion in Gastrointestine of Rats

Japanese journal of pharmacology, 2000, Vol.82 (4), p.350-352

2000

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Effects of KW-5617, a calmodulin inhibitor, on various secretagogues-induced short-circuit current responses in rat colonic mucosa

Japanese Journal of Pharmacology, 1999, Vol.79 (suppl.1), p.207-207

1999

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Effects of KW-5617 (zaldaride maleate) on secretory diarrhea and gastrointestinal propulsion in rats

Japanese Journal of Pharmacology, 1998, Vol.76 (suppl.2), p.297-297

1998

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Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Visceral Pain Reflex Induced by Small Intestinal Distention in Anesthetized Rats

The Japanese Journal of Pharmacology, 1999, Vol.81(4), pp.381-387

1999

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Effect of Zaldaride Maleate, an Antidiarrheal Compound, on 16, 16-Dimethyl Prostaglandin E2-Induced Intestinal Ion Secretion in Rats

The Japanese Journal of Pharmacology, 2000, Vol.83(3), pp.269-272

2000

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Effects of Zaldaride Maleate, an Antidiarrheal Compound, on Intracellular Ca2+-Mediated Short-Circuit Current Response in the Rat Colonic Mucosa

The Japanese Journal of Pharmacology, 2000, Vol.83(1), pp.86-88

2000

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P-16 Embryonic stem cell test using human iPS cells-thalidomide embryotoxicity

Alternatives to Animal Testing and Experimentation, 2013-12, Vol.18 (suppl), p.179-179

2013

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Pharmacological properties of KW-3433, a new angiotensin II receptor antagonist

Japanese Journal of Pharmacology, 1994, Vol.64 (suppl.2), p.337-337

1994

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Effects of Zaldaride Maleate, an Antidiarrheal Compound, on Intracellular Ca^2+ -Mediated Short-Circuit Current Response in the Rat Colonic Mucosa

Japanese Journal of Pharmacology, 2000-05, Vol.83 (1), p.86-88

2000

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Effect of Zaldaride Maleate, an Antidiarrheal Compound, on 16,16-Dimethyl Prostaglandin E_2 -Induced Intestinal Ion Secretion in Rats

Japanese Journal of Pharmacology, 2000-07, Vol.83 (3), p.269-272

2000

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Antidiarrheal Effects of Zaldaride Maleate After Oral, Intravenous and Subcutaneous Administration to Rats

Japanese journal of pharmacology, 1999, Vol.81 (4), p.397-400

1999

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P-588 - Pharmacological properties of KW-3433, a new angiotensin II receptor antagonist

Japanese journal of pharmacology, 1994, Vol.64, p.337-337

1994

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Possible involvement of prostaglandins in α2-mediated uterine contraction

Japanese journal of pharmacology, 1988, Vol.46, p.163-163

1988

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Possible involvement of prostaglandins in α_2 -mediated uterine contraction

Japanese Journal of Pharmacology, 1988, Vol.46 (suppl), p.163-163

1988

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A family of glycosyl hydrolase family 45 cellulases from the pine wood nematode Bursaphelenchus xylophilus

FEBS letters, 2004-08, Vol.572 (1-3), p.201-205

2004

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Lectin ZG16p inhibits proliferation of human colorectal cancer cells via its carbohydrate-binding sites

Glycobiology (Oxford), 2018-12, Vol.28 (1), p.21-31

2018

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Monocytic Leukemia Zinc Finger (MOZ) Interacts with p53 to Induce p21 Expression and Cell-cycle Arrest

The Journal of biological chemistry, 2009-01, Vol.284 (1), p.237-244

2009

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Overexpression of fatty acid synthase in human urinary bladder cancer and combined expression of the synthase and Ki-67 as a predictor of prognosis of cancer patients

Medical molecular morphology, 2011-09, Vol.44 (3), p.146-150

2011

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Thrombomodulin alfa in the treatment of infectious patients complicated by disseminated intravascular coagulation: subanalysis from the phase 3 trial

Shock (Augusta, Ga.), 2011-04, Vol.35 (4), p.349-354

2011

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Discovery of Potent Mcl-1/Bcl-xL Dual Inhibitors by Using a Hybridization Strategy Based on Structural Analysis of Target Proteins

Journal of medicinal chemistry, 2013-12, Vol.56 (23), p.9635-9645

2013

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A novel screening test to predict the developmental toxicity of drugs using human induced pluripotent stem cells

A Simple Protocol for the Myocardial Differentiation of Human iPS Cells

Predicting clinical cardiotoxicity caused by trastuzumab and E-8010 using human cardiomyocytes

The utility of human iPS cell-derived cardiomyocytes in predicting the clinical risk of drugs that display discordance of cardiotoxicity by species

Detection of Thalidomide Embryotoxicity by In Vitro Embryotoxicity Testing Based on Human iPS Cells

Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Fecal Pellet Output Induced by Hyperpropulsion in Gastrointestine of Rats

Effects of KW-5617, a calmodulin inhibitor, on various secretagogues-induced short-circuit current responses in rat colonic mucosa

Effects of KW-5617 (zaldaride maleate) on secretory diarrhea and gastrointestinal propulsion in rats

Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Visceral Pain Reflex Induced by Small Intestinal Distention in Anesthetized Rats

Effect of Zaldaride Maleate, an Antidiarrheal Compound, on 16, 16-Dimethyl Prostaglandin E2-Induced Intestinal Ion Secretion in Rats

Effects of Zaldaride Maleate, an Antidiarrheal Compound, on Intracellular Ca2+-Mediated Short-Circuit Current Response in the Rat Colonic Mucosa

P-16 Embryonic stem cell test using human iPS cells-thalidomide embryotoxicity

Pharmacological properties of KW-3433, a new angiotensin II receptor antagonist

Effects of Zaldaride Maleate, an Antidiarrheal Compound, on Intracellular Ca^2+ -Mediated Short-Circuit Current Response in the Rat Colonic Mucosa

Effect of Zaldaride Maleate, an Antidiarrheal Compound, on 16,16-Dimethyl Prostaglandin E_2 -Induced Intestinal Ion Secretion in Rats

Antidiarrheal Effects of Zaldaride Maleate After Oral, Intravenous and Subcutaneous Administration to Rats

P-588 - Pharmacological properties of KW-3433, a new angiotensin II receptor antagonist

Possible involvement of prostaglandins in α2-mediated uterine contraction

Possible involvement of prostaglandins in α_2 -mediated uterine contraction

A family of glycosyl hydrolase family 45 cellulases from the pine wood nematode Bursaphelenchus xylophilus

Lectin ZG16p inhibits proliferation of human colorectal cancer cells via its carbohydrate-binding sites

Monocytic Leukemia Zinc Finger (MOZ) Interacts with p53 to Induce p21 Expression and Cell-cycle Arrest

Overexpression of fatty acid synthase in human urinary bladder cancer and combined expression of the synthase and Ki-67 as a predictor of prognosis of cancer patients

Thrombomodulin alfa in the treatment of infectious patients complicated by disseminated intravascular coagulation: subanalysis from the phase 3 trial

Discovery of Potent Mcl-1/Bcl-xL Dual Inhibitors by Using a Hybridization Strategy Based on Structural Analysis of Target Proteins

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