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An Orally Bioavailable (Mice) Prodrug of Glutathione

Antioxidants, 2021-06, Vol.10 (6), p.939

2021

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Sequestration and Elimination of Toxic Aldehydes

Chemical research in toxicology, 2020-03, Vol.33 (3), p.764-768

2020

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Development of sulfanegen for mass cyanide casualties

Annals of the New York Academy of Sciences, 2016-06, Vol.1374 (1), p.202-209

2016

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Cyanide Antidotes for Mass Casualties: Water-Soluble Salts of the Dithiane (Sulfanegen) from 3‑Mercaptopyruvate for Intramuscular Administration

Journal of medicinal chemistry, 2013-02, Vol.56 (3), p.1346-1349

2013

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Cyanide Toxicity in Juvenile Pigs and Its Reversal by a New Prodrug, Sulfanegen Sodium

Anesthesia and analgesia, 2012-05, Vol.114 (5), p.956-961

2012

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Sulfanegen sodium treatment in a rabbit model of sub-lethal cyanide toxicity

Toxicology and applied pharmacology, 2010-11, Vol.248 (3), p.269-276

2010

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Novel, Orally Effective Cyanide Antidotes

Journal of medicinal chemistry, 2007-12, Vol.50 (26), p.6462-6464

2007

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Donors of HNO

Current topics in medicinal chemistry, 2005-01, Vol.5 (7), p.649-664

2005

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Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

Biochemistry (Easton), 1998-04, Vol.37 (16), p.5362-5371

1998

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Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase

Journal of medicinal chemistry, 1992-10, Vol.35 (20), p.3648-3652

1992

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Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids

Journal of medicinal chemistry, 1987-10, Vol.30 (10), p.1891-1896

1987

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Reaction of Nitric Oxide with the Free Sulfhydryl Group of Human Serum Albumin Yields a Sulfenic Acid and Nitrous Oxide

Biochemistry (Easton), 1995-09, Vol.34 (36), p.11494-11499

1995

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Hepatoprotection by L-cysteine-glutathione mixed disulfide, a sulfhydryl-modified prodrug of glutathione

Journal of biochemical and molecular toxicology, 2003, Vol.17 (2), p.95-97

2003

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Carbethoxylating Agents as Inhibitors of Aldehyde Dehydrogenase

Journal of medicinal chemistry, 1995-05, Vol.38 (11), p.1872-1876

1995

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Mechanism for the inhibition of aldehyde dehydrogenase by nitric oxide

Alcohol (Fayetteville, N.Y.), 1997-03, Vol.14 (2), p.181-189

1997

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Inhibition of ALDH3A1-catalyzed oxidation by chlorpropamide analogues

Chemico-biological interactions, 2001-01, Vol.130 (1-3), p.135-149

2001

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Prodrugs of L-cysteine as liver-protective agents. 2(R,S)-methylthiazolidine-4(R)-carboxylic acid (MTCA), a latent cysteine

Journal of medicinal chemistry, 1982-05, Vol.25 (5), p.489-491

1982

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Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

Biochemistry (Easton), 1998-12, Vol.37 (51), p.18129-18129

1998

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Prodrugs of Nitroxyl as Potential Aldehyde Dehydrogenase Inhibitors vis-a-vis Vascular Smooth Muscle Relaxants

Journal of medicinal chemistry, 1995-05, Vol.38 (11), p.1865-1871

1995

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Augmentation of Human and Rat Lenticular Glutathione in Vitro by Prodrugs of γ-l-Glutamyl-l-cysteine

Journal of medicinal chemistry, 1996-04, Vol.39 (8), p.1676-1681

1996

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Mechanisms of Inhibition of Aldehyde Dehydrogenase by Nitroxyl, the Active Metabolite of the Alcohol Deterrent Agent Cyanamide

Biochemical pharmacology, 1998-06, Vol.55 (12), p.2007-2015

1998

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A Beckmann-type dehydration of n-butyraldoxime catalyzed by cytochrome P-450

Journal of organic chemistry, 1992-09, Vol.57 (19), p.5074-5075

1992

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Glutaramyl-.beta.-alanyl Spacer Group for Haptenic Coupling to Proteins. Preparation of Immunogens for Antibody Production against Polychlorinated Biphenyls

Bioconjugate chemistry, 1994-09, Vol.5 (5), p.418-422

1994

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Intermolecular decomposition of N-acylcyanamides

Journal of organic chemistry, 1990-05, Vol.55 (10), p.3403-3406

1990

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Acyl, N-protected .alpha.-aminoacyl, and peptidyl derivatives as prodrug forms of the alcohol deterrent agent cyanamide

Journal of medicinal chemistry, 1986-10, Vol.29 (10), p.1922-1929

1986

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An Orally Bioavailable (Mice) Prodrug of Glutathione

Sequestration and Elimination of Toxic Aldehydes

Development of sulfanegen for mass cyanide casualties

Cyanide Antidotes for Mass Casualties: Water-Soluble Salts of the Dithiane (Sulfanegen) from 3‑Mercaptopyruvate for Intramuscular Administration

Cyanide Toxicity in Juvenile Pigs and Its Reversal by a New Prodrug, Sulfanegen Sodium

Sulfanegen sodium treatment in a rabbit model of sub-lethal cyanide toxicity

Novel, Orally Effective Cyanide Antidotes

Donors of HNO

Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase

Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids

Reaction of Nitric Oxide with the Free Sulfhydryl Group of Human Serum Albumin Yields a Sulfenic Acid and Nitrous Oxide

Hepatoprotection by L-cysteine-glutathione mixed disulfide, a sulfhydryl-modified prodrug of glutathione

Carbethoxylating Agents as Inhibitors of Aldehyde Dehydrogenase

Mechanism for the inhibition of aldehyde dehydrogenase by nitric oxide

Inhibition of ALDH3A1-catalyzed oxidation by chlorpropamide analogues

Prodrugs of L-cysteine as liver-protective agents. 2(R,S)-methylthiazolidine-4(R)-carboxylic acid (MTCA), a latent cysteine

Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

Prodrugs of Nitroxyl as Potential Aldehyde Dehydrogenase Inhibitors vis-a-vis Vascular Smooth Muscle Relaxants

Augmentation of Human and Rat Lenticular Glutathione in Vitro by Prodrugs of γ-l-Glutamyl-l-cysteine

Mechanisms of Inhibition of Aldehyde Dehydrogenase by Nitroxyl, the Active Metabolite of the Alcohol Deterrent Agent Cyanamide

A Beckmann-type dehydration of n-butyraldoxime catalyzed by cytochrome P-450

Glutaramyl-.beta.-alanyl Spacer Group for Haptenic Coupling to Proteins. Preparation of Immunogens for Antibody Production against Polychlorinated Biphenyls

Intermolecular decomposition of N-acylcyanamides

Acyl, N-protected .alpha.-aminoacyl, and peptidyl derivatives as prodrug forms of the alcohol deterrent agent cyanamide

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