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Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1
- Schoepfer, Joseph
- Jahnke, Wolfgang
- Berellini, Giuliano
- Buonamici, Silvia
- Cotesta, Simona
- Cowan-Jacob, Sandra W
- Dodd, Stephanie
- Drueckes, Peter
- Fabbro, Doriano
- Gabriel, Tobias
- Groell, Jean-Marc
- Grotzfeld, Robert M
- Hassan, A. Quamrul
- Henry, Chrystèle
- Iyer, Varsha
- Jones, Darryl
- Lombardo, Franco
- Loo, Alice
- Manley, Paul W
- Pellé, Xavier
- Rummel, Gabriele
- Salem, Bahaa
- Warmuth, Markus
- Wylie, Andrew A
- Zoller, Thomas
- Marzinzik, Andreas L
- Furet, Pascal
2018
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Nature (London), 2017-03, Vol.543 (7647), p.733-737
- Wylie, Andrew A.
- Schoepfer, Joseph
- Jahnke, Wolfgang
- Cowan-Jacob, Sandra W.
- Loo, Alice
- Furet, Pascal
- Marzinzik, Andreas L.
- Pelle, Xavier
- Donovan, Jerry
- Zhu, Wenjing
- Buonamici, Silvia
- Hassan, A. Quamrul
- Lombardo, Franco
- Iyer, Varsha
- Palmer, Michael
- Berellini, Giuliano
- Dodd, Stephanie
- Thohan, Sanjeev
- Bitter, Hans
- Branford, Susan
- Ross, David M.
- Hughes, Timothy P.
- Petruzzelli, Lilli
- Vanasse, K. Gary
- Warmuth, Markus
- Hofmann, Francesco
- Keen, Nicholas J.
- Sellers, William R.
2017
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Cancer research (Chicago, Ill.), 2009-05, Vol.69 (10), p.4286-4293
2009
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Cell cycle (Georgetown, Tex.), 2009-02, Vol.8 (3), p.498-504
2009
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Cancer research (Chicago, Ill.), 2011-04, Vol.71 (7), p.2643-2653
2011
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Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (41), p.17135-17140
2011
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Science advances, 2020-06, Vol.6 (25), p.eabb2210-eabb2210
- Fassl, Anne
- Brain, Christopher
- Abu-Remaileh, Monther
- Stukan, Iga
- Butter, Deborah
- Stepien, Piotr
- Feit, Avery S
- Bergholz, Johann
- Michowski, Wojciech
- Otto, Tobias
- Sheng, Qing
- Loo, Alice
- Michael, Walter
- Tiedt, Ralph
- DeAngelis, Carmine
- Schiff, Rachel
- Jiang, Baishan
- Jovanovic, Bojana
- Nowak, Karolina
- Ericsson, Maria
- Cameron, Michael
- Gray, Nathanael
- Dillon, Deborah
- Zhao, Jean J
- Sabatini, David M
- Jeselsohn, Rinath
- Brown, Myles
- Polyak, Kornelia
- Sicinski, Piotr
2020
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Cancer research (Chicago, Ill.), 2010-07, Vol.70 (13), p.5528-5538
2010
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Oncotarget, 2013-06, Vol.4 (6), p.816-829
2013
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Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.872-872
2016
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Clinical cancer research, 2021-01, Vol.27 (1), p.342-354
- Liu, Chen
- Lu, Hengyu
- Wang, Hongyun
- Loo, Alice
- Zhang, Xiamei
- Yang, Guizhi
- Kowal, Colleen
- Delach, Scott
- Wang, Ye
- Goldoni, Silvia
- Hastings, William D
- Wong, Karrie
- Gao, Hui
- Meyer, Matthew J
- Moody, Susan E
- LaMarche, Matthew J
- Engelman, Jeffrey A
- Williams, Juliet A
- Hammerman, Peter S
- Abrams, Tinya J
- Mohseni, Morvarid
- Caponigro, Giordano
- Hao, Huai-Xiang
2021
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Nature medicine, 2015-11, Vol.21 (11), p.1318-1325
- Gao, Hui
- Korn, Joshua M
- Ferretti, Stéphane
- Monahan, John E
- Wang, Youzhen
- Singh, Mallika
- Zhang, Chao
- Schnell, Christian
- Yang, Guizhi
- Zhang, Yun
- Balbin, O Alejandro
- Barbe, Stéphanie
- Cai, Hongbo
- Casey, Fergal
- Chatterjee, Susmita
- Chiang, Derek Y
- Chuai, Shannon
- Cogan, Shawn M
- Collins, Scott D
- Dammassa, Ernesta
- Ebel, Nicolas
- Embry, Millicent
- Green, John
- Kauffmann, Audrey
- Kowal, Colleen
- Leary, Rebecca J
- Lehar, Joseph
- Liang, Ying
- Loo, Alice
- Lorenzana, Edward
- Robert McDonald, E
- McLaughlin, Margaret E
- Merkin, Jason
- Meyer, Ronald
- Naylor, Tara L
- Patawaran, Montesa
- Reddy, Anupama
- Röelli, Claudia
- Ruddy, David A
- Salangsang, Fernando
- Santacroce, Francesca
- Singh, Angad P
- Tang, Yan
- Tinetto, Walter
- Tobler, Sonja
- Velazquez, Roberto
- Venkatesan, Kavitha
- Von Arx, Fabian
- Wang, Hui Qin
- Wang, Zongyao
- Wiesmann, Marion
- Wyss, Daniel
- Xu, Fiona
- Bitter, Hans
- Atadja, Peter
- Lees, Emma
- Hofmann, Francesco
- Li, En
- Keen, Nicholas
- Cozens, Robert
- Jensen, Michael Rugaard
- Pryer, Nancy K
- Williams, Juliet A
- Sellers, William R
2015
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Nature (London), 2010-02, Vol.463 (7283), p.899-905
- Yecies, Derek
- Gabriel, Stacey
- Porter, Dale
- Nucera, Carmelo
- Antonescu, Cristina R
- Chiang, Derek Y
- Janne, Pasi A
- Greulich, Heidi
- Loo, Alice
- Prensner, John
- Maher, Elizabeth
- Rustgi, Anil K
- Ligon, Azra H
- Tanaka, Kumiko E
- Kaye, Frederic J
- Ebert, Benjamin L
- Pomeroy, Scott L
- Lander, Eric S
- Fletcher, Jonathan A
- Okamoto, Aikou
- Signoretti, Sabina
- Haery, Leila
- Reich, Michael
- Dobson, Jennifer
- Raychaudhuri, Soumya
- Wei, Guo
- Baselga, José
- Tsao, Ming-Sound
- Letai, Anthony
- Getz, Gad
- Liefeld, Ted
- Donovan, Jerry
- Levine, Ross L
- Beer, David G
- Daly, Mark J
- Sasaki, Hidefumi
- Pinchback, Reid M
- Bass, Adam J
- Hoffman, Carter
- Ladanyi, Marc
- True, Lawrence D
- Cho, Yoon-Jae
- Sellers, William R
- Tabernero, Josep
- Demichelis, Francesca
- Tepper, Joel E
- Golub, Todd R
- Meyerson, Matthew
- Boehm, Jesse S
- Mermel, Craig H
- Loda, Massimo
- Weir, Barbara A
- Beroukhim, Rameen
- Singer, Samuel
- Urashima, Mitsuyoshi
- Gao, Qing
- Lawrence, Michael S
- Rubin, Mark A
- Barretina, Jordi
- Garraway, Levi A
- Winckler, Wendy
- Mc Henry, Kevin T
2010
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Angewandte Chemie International Edition, 2022-11, Vol.61 (46), p.e202117276-n/a
International ed. in English, 2022
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Blood, 2020-11, Vol.136 (Supplement 1), p.34-35
2020
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Oncotarget, 2018-10, Vol.9 (81), p.35226-35240
2018
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Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.2790-2818
- Burks, Heather E
- Abrams, Tinya
- Kirby, Christina A
- Baird, Jason
- Fekete, Alexander
- Hamann, Lawrence G
- Kim, Sunkyu
- Lombardo, Franco
- Loo, Alice
- Lubicka, Danuta
- Macchi, Kaitlin
- McDonnell, Donald P
- Mishina, Yuji
- Norris, John D
- Nunez, Jill
- Saran, Chitra
- Sun, Yingchuan
- Thomsen, Noel M
- Wang, Chunrong
- Wang, Jianling
- Peukert, Stefan
2017
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Cancer research (Chicago, Ill.), 2020-10, Vol.80 (19), p.4278-4287
- Palmer, Adam C
- Plana, Deborah
- Gao, Hui
- Korn, Joshua M
- Yang, Guizhi
- Green, John
- Zhang, Xiamei
- Velazquez, Roberto
- McLaughlin, Margaret E
- Ruddy, David A
- Kowal, Colleen
- Muszynski, Julie
- Bullock, Caroline
- Rivera, Stacy
- Rakiec, Daniel P
- Elliott, GiNell
- Fordjour, Paul
- Meyer, Ronald
- Loo, Alice
- Kurth, Esther
- Engelman, Jeffrey A
- Bitter, Hans
- Sellers, William R
- Williams, Juliet A
- Sorger, Peter K
2020
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Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.922-922
2019
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Oncotarget, 2020-01, Vol.11 (4), p.443-451
2020
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Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.682-682
2014
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International journal of developmental neuroscience, 1996-11, Vol.14 (7-8), p.881-900
1996
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Angewandte Chemie, 2022-11, Vol.134 (46), p.n/a
2022
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Oncotarget, 2020-04, Vol.11 (14), p.1289-1289
2020
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Nature (London), 2017-03, Vol.543 (7647), p.733
- Wylie, Andrew A
- Schoepfer, Joseph
- Jahnke, Wolfgang
- Cowan-Jacob, Sandra W
- Loo, Alice
- Furet, Pascal
- Marzinzik, Andreas L
- Pelle, Xavier
- Donovan, Jerry
- Zhu, Wenjing
- Buonamici, Silvia
- Hassan, A. Quamrul
- Lombardo, Franco
- Iyer, Varsha
- Palmer, Michael
- Berellini, Giuliano
- Dodd, Stephanie
- Thohan, Sanjeev
- Bitter, Hans
- Branford, Susan
- Ross, David M
- Hughes, Timothy P
- Petruzzelli, Lilli
- Vanasse, K. Gary
- Warmuth, Markus
- Hofmann, Francesco
- Keen, Nicholas J
- Sellers, William R
2017
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