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IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias

PloS one, 2016-08, Vol.11 (8), p.e0161158-e0161158

2016

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Leukemia stem cells in T-ALL require active Hif1α and Wnt signaling

Blood, 2015-06, Vol.125 (25), p.3917-3927

2015

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Metformin Pharmacokinetics in Mouse Tumors: Implications for Human Therapy

Cell metabolism, 2016-04, Vol.23 (4), p.567-568

2016

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ShcA signalling is essential for tumour progression in mouse models of human breast cancer

The EMBO journal, 2008-03, Vol.27 (6), p.910-920

2008

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Insulin receptor loss impairs mammary tumorigenesis in mice

Cell reports (Cambridge), 2023-11, Vol.42 (11), p.113251-113251, Article 113251

2023

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Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity

Cell stem cell, 2018-11, Vol.23 (5), p.714-726.e7

2018

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NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species

Nature medicine, 2012-11, Vol.18 (11), p.1693-1698

2012

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Inducible and coupled expression of the polyomavirus middle T antigen and Cre recombinase in transgenic mice: an in vivo model for synthetic viability in mammary tumour progression

Breast cancer research : BCR, 2014-01, Vol.16 (1), p.R11-R11, Article R11

2014

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Distinct ErbB-2 coupled signaling pathways promote mammary tumors with unique pathologic and transcriptional profiles

Cancer research (Chicago, Ill.), 2007-08, Vol.67 (16), p.7579-7588

2007

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87: Patient Reported Outcomes During Head and Neck Cancer Radiotherapy Using the MD Anderson Symptom Inventory-Head and Neck Module (MDASI-HN)

Radiotherapy and oncology, 2022-09, Vol.174, p.S38-S39

2022

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Abstract 664: Insulin receptor signaling contributes to mammary tumorigenesis in mice

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.664-664

2016

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Leukemia-Initiating Activity in T-ALL Requires Active Hif1a and Wnt Signaling

Blood, 2014-12, Vol.124 (21), p.57-57

2014

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Ultrasensitive Detection of NOTCH1 c.7544_7545delCT Mutations in Chronic Lymphocytic Leukemia by Droplet Digital PCR Reveals High Frequency of Subclonal Mutations and Predicts Clinical Outcome in Cases with Trisomy 12

The Journal of molecular diagnostics : JMD, 2020-04, Vol.22 (4), p.571-578

2020

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NOTCH1 Induces Differential Epigenomic Patterning and Genomic Organization in Fetal Liver- and Adult Bone Marrow-Derived Hematopoietic Progentiors

Blood, 2015-12, Vol.126 (23), p.3637-3637

2015

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Fetal Vs. Adult Hematopoietic Progenitors Respond Differently to NOTCH1: Implications for Pediatric Vs. Adult T-ALL

Blood, 2012-11, Vol.120 (21), p.2381-2381

2012

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Collaboration Between RUNX and NOTCH Pathways in T-Cell Acute Lymphoblastic Leukemia

Blood, 2012-11, Vol.120 (21), p.1279-1279

2012

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Receptor Tyrosine Kinase Signaling Favors a Protumorigenic State in Breast Cancer Cells by Inhibiting the Adaptive Immune Response

Cancer research (Chicago, Ill.), 2010-10, Vol.70 (20), p.7776-7787

2010

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NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-[theta] and reactive oxygen species

Nature medicine, 2012-11, Vol.18 (11), p.1693-1698

2012

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PKCθ Regulates T-Cell Leukemia-Initiating Activity via Reactive Oxygen Species

Nature medicine, 2012-10, Vol.18 (11), p.1693-1698

2012

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Notch-Mediated Suppression of PKCθ Reduces Reactive Oxygen Species and Promotes Leukemic Stem Cell Activity In T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Blood, 2010-11, Vol.116 (21), p.12-12

2010

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Distinct erbn-2-coupled signaling pathways promote mammary tumors with unique pathologic and transcriptional profiles

Cancer research (Chicago, Ill.), 2007, Vol.67 (16), p.7579-7588

2007

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Neu tyrosine autophosphorylation site mutants exhibit similar and distinct mammary tumour phenotypes

Lam, Sonya Hoan Linh

2008

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Partnering with Clinical Pharmacologists to Improve Medication Use in Children

The Journal of pediatrics, 2020-12, Vol.227, p.5-8

2020

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Diabetic Wound Keratinocytes Induce Macrophage JMJD3-Mediated Nlrp3 Expression via IL-1R Signaling

Diabetes (New York, N.Y.), 2024-09, Vol.73 (9), p.1462-1472

2024

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Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair

Cellular & molecular immunology, 2022-11, Vol.19 (11), p.1251-1262

2022

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IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias

Leukemia stem cells in T-ALL require active Hif1α and Wnt signaling

Metformin Pharmacokinetics in Mouse Tumors: Implications for Human Therapy

ShcA signalling is essential for tumour progression in mouse models of human breast cancer

Insulin receptor loss impairs mammary tumorigenesis in mice

Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity

NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species

Inducible and coupled expression of the polyomavirus middle T antigen and Cre recombinase in transgenic mice: an in vivo model for synthetic viability in mammary tumour progression

Distinct ErbB-2 coupled signaling pathways promote mammary tumors with unique pathologic and transcriptional profiles

87: Patient Reported Outcomes During Head and Neck Cancer Radiotherapy Using the MD Anderson Symptom Inventory-Head and Neck Module (MDASI-HN)

Abstract 664: Insulin receptor signaling contributes to mammary tumorigenesis in mice

Leukemia-Initiating Activity in T-ALL Requires Active Hif1a and Wnt Signaling

Ultrasensitive Detection of NOTCH1 c.7544_7545delCT Mutations in Chronic Lymphocytic Leukemia by Droplet Digital PCR Reveals High Frequency of Subclonal Mutations and Predicts Clinical Outcome in Cases with Trisomy 12

NOTCH1 Induces Differential Epigenomic Patterning and Genomic Organization in Fetal Liver- and Adult Bone Marrow-Derived Hematopoietic Progentiors

Fetal Vs. Adult Hematopoietic Progenitors Respond Differently to NOTCH1: Implications for Pediatric Vs. Adult T-ALL

Collaboration Between RUNX and NOTCH Pathways in T-Cell Acute Lymphoblastic Leukemia

Receptor Tyrosine Kinase Signaling Favors a Protumorigenic State in Breast Cancer Cells by Inhibiting the Adaptive Immune Response

NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-[theta] and reactive oxygen species

PKCθ Regulates T-Cell Leukemia-Initiating Activity via Reactive Oxygen Species

Notch-Mediated Suppression of PKCθ Reduces Reactive Oxygen Species and Promotes Leukemic Stem Cell Activity In T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Distinct erbn-2-coupled signaling pathways promote mammary tumors with unique pathologic and transcriptional profiles

Neu tyrosine autophosphorylation site mutants exhibit similar and distinct mammary tumour phenotypes

Partnering with Clinical Pharmacologists to Improve Medication Use in Children

Diabetic Wound Keratinocytes Induce Macrophage JMJD3-Mediated Nlrp3 Expression via IL-1R Signaling

Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair

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