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HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-Driven Medulloblastoma

Cancer cell, 2016-03, Vol.29 (3), p.311-323

2016

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Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2‑Thiohydantoin Compounds

Journal of medicinal chemistry, 2015-09, Vol.58 (17), p.6899-6908

2015

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Soy isoflavones and immunity

The Journal of Medical Investigation, 2008, Vol.55(3,4), pp.167-173

2008

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Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases: Synthesis, Structure–Activity Relationship, and Selective Antitumor Activity

Journal of medicinal chemistry, 2014-10, Vol.57 (20), p.8307-8318

2014

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Epigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas

Nature communications, 2022-11, Vol.13 (1), p.6689-6689, Article 6689

2022

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Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models

Clinical cancer research, 2018-05, Vol.24 (9), p.2159-2170

2018

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Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models

Journal of translational medicine, 2023-07, Vol.21 (1), p.444-444, Article 444

2023

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IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma

PloS one, 2018-04, Vol.13 (4), p.e0193565-e0193565

2018

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Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Primary and Recurrent Meningioma

Cancers, 2020-06, Vol.12 (6), p.1478

2020

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Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma

Translational oncology, 2022-04, Vol.18, p.101368-101368, Article 101368

2022

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A chemical screen for medulloblastoma identifies quercetin as a putative radiosensitizer

Oncotarget, 2016-06, Vol.7 (24), p.35776-35788

2016

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Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion

Advanced science, 2021-12, Vol.8 (23), p.e2101923-n/a

2021

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Chitin particles induce size-dependent but carbohydrate-independent innate eosinophilia

Journal of leukocyte biology, 2011-07, Vol.90 (1), p.167-176

2011

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Inhibition of Mutated Isocitrate Dehydrogenase 1 in Cancer

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2018-01, Vol.14 (7), p.715-724

2018

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Cholera Toxin Induces a Shift from Inactive to Active Cyclooxygenase 2 in Alveolar Macrophages Activated by Mycobacterium bovis BCG

Infection and Immunity, 2013-01, Vol.81 (1), p.373-380

2013

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Control of nodule number by the phytohormone abscisic acid in the roots of two leguminous species

Plant and cell physiology, 2004-07, Vol.45 (7), p.914-922

2004

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MBRS-56. SYSTEMATIC DRUG REPURPOSING IDENTIFIES DIGOXIN AS A DRUG THAT PROLONGS SURVIVAL IN PDOX MODELS OF GROUPS 3 AND 4 MEDULLOBLASTOMA AT CLINICALLY RELEVANT DOSES

Neuro-oncology (Charlottesville, Va.), 2018-06, Vol.20 (suppl_2), p.i140-i140

2018

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DISP-16. RACIAL/ETHNIC DIFFERENCES OF PEDIATRIC BRAIN TUMORS IN PATIENT DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODEL DEVELOPMENT AND DRUG RESPONSES DETECTED BY HIGH-THROUGHPUT DRUG SCREENING

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v140-v140

2023

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DDIS-18. TARGETING DIPGs THROUGH SUPER-ACTIVATION OF STEROID RECEPTOR CO-ACTIVATOR: AN IN VIVO STUDY IN PATIENT-DERIVED INTRA-BRAIN STEM XENOGRAFT MOUSE MODELS

Neuro-oncology (Charlottesville, Va.), 2017-11, Vol.19 (suppl_6), p.vi62-vi62

2017

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Genistein suppresses development of spontaneous atopic-like dermatitis in NC/Nga mice

Journal of Nutritional Science and Vitaminology, 2006, Vol.52(4), pp.293-296

2006

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Dissection, Histological Processing, and Gene Expression Analysis of Murine Supraclavicular Brown Adipose Tissue

Journal of visualized experiments, 2024-03 (205)

2024

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EXTH-49. INTRAVENOUS INJECTION OF ONCOLYTIC PICORNAVIRUS SVV-001 PROLONGS ANIMAL SURVIVAL IN A NOVELPANEL OF PATIENT-DERIVED ORTHOTOPIC XENOGRAFT MOUSE MODELS OF ADULT GLIOBLASTOMA

Neuro-oncology (Charlottesville, Va.), 2016-11, Vol.18 (suppl_6), p.vi69-vi70

2016

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Systems biology-based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma

Science translational medicine, 2018-10, Vol.10 (464)

2018

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CD57 defines a novel cancer stem cell that drive invasion of diffuse pediatric-type high grade gliomas

British journal of cancer, 2024-07, Vol.131 (2), p.258-270

2024

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HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-Driven Medulloblastoma

Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2‑Thiohydantoin Compounds

Soy isoflavones and immunity

Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases: Synthesis, Structure–Activity Relationship, and Selective Antitumor Activity

Epigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas

Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models

Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models

IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma

Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Primary and Recurrent Meningioma

Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma

A chemical screen for medulloblastoma identifies quercetin as a putative radiosensitizer

Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion

Chitin particles induce size-dependent but carbohydrate-independent innate eosinophilia

Inhibition of Mutated Isocitrate Dehydrogenase 1 in Cancer

Cholera Toxin Induces a Shift from Inactive to Active Cyclooxygenase 2 in Alveolar Macrophages Activated by Mycobacterium bovis BCG

Control of nodule number by the phytohormone abscisic acid in the roots of two leguminous species

MBRS-56. SYSTEMATIC DRUG REPURPOSING IDENTIFIES DIGOXIN AS A DRUG THAT PROLONGS SURVIVAL IN PDOX MODELS OF GROUPS 3 AND 4 MEDULLOBLASTOMA AT CLINICALLY RELEVANT DOSES

DISP-16. RACIAL/ETHNIC DIFFERENCES OF PEDIATRIC BRAIN TUMORS IN PATIENT DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODEL DEVELOPMENT AND DRUG RESPONSES DETECTED BY HIGH-THROUGHPUT DRUG SCREENING

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

DDIS-18. TARGETING DIPGs THROUGH SUPER-ACTIVATION OF STEROID RECEPTOR CO-ACTIVATOR: AN IN VIVO STUDY IN PATIENT-DERIVED INTRA-BRAIN STEM XENOGRAFT MOUSE MODELS

Genistein suppresses development of spontaneous atopic-like dermatitis in NC/Nga mice

Dissection, Histological Processing, and Gene Expression Analysis of Murine Supraclavicular Brown Adipose Tissue

EXTH-49. INTRAVENOUS INJECTION OF ONCOLYTIC PICORNAVIRUS SVV-001 PROLONGS ANIMAL SURVIVAL IN A NOVELPANEL OF PATIENT-DERIVED ORTHOTOPIC XENOGRAFT MOUSE MODELS OF ADULT GLIOBLASTOMA

Systems biology-based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma

CD57 defines a novel cancer stem cell that drive invasion of diffuse pediatric-type high grade gliomas

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