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Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model

mAbs, 2020-01, Vol.12 (1), p.1688616-1688616

2020

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Bench‐to‐bedside translation of chimeric antigen receptor (CAR) T cells using a multiscale systems pharmacokinetic‐pharmacodynamic model: A case study with anti‐BCMA CAR‐T

CPT: pharmacometrics and systems pharmacology, 2021-04, Vol.10 (4), p.362-376

2021

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Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N -Acetylgalactosamine-Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans

The Journal of pharmacology and experimental therapeutics, 2021-11, Vol.379 (2), p.134-146

2021

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Development of a Target cell-Biologics-Effector cell (TBE) complex-based cell killing model to characterize target cell depletion by T cell redirecting bispecific agents

mAbs, 2018-08, Vol.10 (6), p.876-889

2018

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Geriatrics 2030: Developing Drugs to Care for Older Persons—A Neglected and Growing Population

Clinical pharmacology and therapeutics, 2020-01, Vol.107 (1), p.53-56

2020

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Imaging studies of biodistribution and kinetics in drug development

Drug development research, 2003-06, Vol.59 (2), p.208-226

2003

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Mapping PET-measured triamcinolone acetonide (TAA) aerosol distribution into deposition by airway generation

International journal of pharmaceutics, 2000-04, Vol.199 (1), p.7-16

2000

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In Vivo Characterization of Inhaled Pharmaceuticals Using Quantitative Positron Emission Tomography

Journal of clinical pharmacology, 1999-08, Vol.39 (S1), p.25S-29S

1999

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Biodistribution and Kinetics of Nasal Carbon-11-Triamcinolone Acetonide

The Journal of nuclear medicine (1978), 1998-11, Vol.39 (11), p.1972-1977

1998

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Visualization of Product Performance in the Gut: What Role in the Drug Development/Regulatory Paradigm?

Journal of clinical pharmacology, 1999-08, Vol.39 (S1), p.6S-9S

1999

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Pharmacoscintigraphic evaluation of a modified release (Geomatrix®) diltiazem formulation

Journal of controlled release, 1995, Vol.33 (1), p.89-97

1995

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Regional distribution and kinetics of inhaled pharmaceuticals

Current pharmaceutical design, 2000-11, Vol.6 (16), p.1631-1651

2000

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A PHARMACOKINETIC AND PHARMACODYNAMIC COMPARISON OF DESMOPRESSIN ADMINISTERED AS WHOLE, CHEWED AND CRUSHED tablets, AND AS AN ORAL SOLUTION

The Journal of urology, 2001-05, p.1446-1451

2001

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Imaging studies of biodistribution and kinetics in drug development: PET and SPECT in Medication Development

Drug development research, 2003, Vol.59 (2), p.208-226

2003

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Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model

mAbs, 2020, Vol.12 (1)

2020

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Development of a Target cell-Biologics-Effector cell (TBE) complex-based cell killing model to characterize target cell depletion by T cell redirecting bispecific agents

mAbs, 2018, Vol.10 (6), p.876-889

2018

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Pharmacoscintigraphic evaluation of a modified release (Geomatrix®) diltiazem formulation: Journal of Controlled Release, 33 (1995) 89–97

Journal of controlled release, 1995-07, Vol.35 (1), p.86-86

1995

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Uptake and distribution of lidocaine in fetal lambs

Anesthesiology (Philadelphia), 1990-03, Vol.72 (3), p.483-489

1990

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The pharmacokinetics and gastrointestinal transit of Cormax once-a-day

International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1992, Vol.19 (1), p.131-132

Heald, Donald L

1992

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The Gastrointestinal Transit and Systemic Absorption of Diltiazem HCL from a Modified Release Dosage Form

Nuclear Imaging in Drug Discovery, Development, and Approval, p.301-320

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Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society on the Recommended Amount of Sleep for a Healthy Adult: Methodology and Discussion

Sleep (New York, N.Y.), 2015-08, Vol.38 (8), p.1161-1183

2015

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Recommended Amount of Sleep for a Healthy Adult: A Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society

Journal of clinical sleep medicine, 2015-06, Vol.11 (6), p.591-592

2015

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Exploring dimethyl sulfide (DMS) oxidation and implications for global aerosol radiative forcing

Atmospheric chemistry and physics, 2022-02, Vol.22 (2), p.1549-1573

2022

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Recommended Amount of Sleep for a Healthy Adult: A Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society

Sleep, 2015-06, Vol.38 (6), p.843-844

2015

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An improved representation of fire non-methane organic gases (NMOGs) in models: emissions to reactivity

Atmospheric chemistry and physics, 2022-09, Vol.22 (18), p.12093-12111

2022

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Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model

Bench‐to‐bedside translation of chimeric antigen receptor (CAR) T cells using a multiscale systems pharmacokinetic‐pharmacodynamic model: A case study with anti‐BCMA CAR‐T

Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N -Acetylgalactosamine-Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans

Development of a Target cell-Biologics-Effector cell (TBE) complex-based cell killing model to characterize target cell depletion by T cell redirecting bispecific agents

Geriatrics 2030: Developing Drugs to Care for Older Persons—A Neglected and Growing Population

Imaging studies of biodistribution and kinetics in drug development

Mapping PET-measured triamcinolone acetonide (TAA) aerosol distribution into deposition by airway generation

In Vivo Characterization of Inhaled Pharmaceuticals Using Quantitative Positron Emission Tomography

Biodistribution and Kinetics of Nasal Carbon-11-Triamcinolone Acetonide

Visualization of Product Performance in the Gut: What Role in the Drug Development/Regulatory Paradigm?

Pharmacoscintigraphic evaluation of a modified release (Geomatrix®) diltiazem formulation

Regional distribution and kinetics of inhaled pharmaceuticals

A PHARMACOKINETIC AND PHARMACODYNAMIC COMPARISON OF DESMOPRESSIN ADMINISTERED AS WHOLE, CHEWED AND CRUSHED tablets, AND AS AN ORAL SOLUTION

Imaging studies of biodistribution and kinetics in drug development: PET and SPECT in Medication Development

Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model

Development of a Target cell-Biologics-Effector cell (TBE) complex-based cell killing model to characterize target cell depletion by T cell redirecting bispecific agents

Pharmacoscintigraphic evaluation of a modified release (Geomatrix®) diltiazem formulation: Journal of Controlled Release, 33 (1995) 89–97

Uptake and distribution of lidocaine in fetal lambs

The pharmacokinetics and gastrointestinal transit of Cormax once-a-day

The Gastrointestinal Transit and Systemic Absorption of Diltiazem HCL from a Modified Release Dosage Form

Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society on the Recommended Amount of Sleep for a Healthy Adult: Methodology and Discussion

Recommended Amount of Sleep for a Healthy Adult: A Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society

Exploring dimethyl sulfide (DMS) oxidation and implications for global aerosol radiative forcing

Recommended Amount of Sleep for a Healthy Adult: A Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society

An improved representation of fire non-methane organic gases (NMOGs) in models: emissions to reactivity

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