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Port-a-patch and patchliner: high fidelity electrophysiology for secondary screening and safety pharmacology

Combinatorial chemistry & high throughput screening, 2009-01, Vol.12 (1), p.24-37

2009

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Automated patch clamp in drug discovery: major breakthroughs and innovation in the last decade

Expert opinion on drug discovery, 2021-01, Vol.16 (1), p.1-5

2021

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KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury

PloS one, 2014-07, Vol.9 (7), p.e103402

2014

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Accessing intracellular membrane transport proteins: a novel electrophysiological approach for lysosomal and mitochondrial channels and transporters

Biophysical journal, 2022-02, Vol.121 (3), p.26a-26a

2022

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Mechanical activation of PIEZO1 channels using high throughput electrophysiology

Biophysical journal, 2024-02, Vol.123 (3), p.261a-261a

2024

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Drug Effects On Human Na(+)/Ca(2+)Exchanger and Implications for Drug Development

Biophysical journal, 2021-02, Vol.120 (3), p.74a-74a

2021

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Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca2+ Currents in Isolated Lysosomes

The Journal of biological chemistry, 2010-07, Vol.285 (28), p.21219-21222

2010

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Mechanical and pharmacological activation of PIEZO1 channels characterized by high throughput electrophysiology

Biophysical journal, 2022-02, Vol.121 (3), p.505a-505a

2022

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A Novel Gain of Function Mutation of Piezo-1 is Investigated in Red Blood Cells by High-Throughput Patch Clamp

Biophysical journal, 2019-02, Vol.116 (3), p.244a-245a

2019

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Novel small-molecule modulation of PIEZO1 investigated by conventional and automated patch-clamp

Biophysical journal, 2023-02, Vol.122 (3), p.396a-396a

2023

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Pharmacology of P2X3 and P2X2/3 receptors: An automated patch clamp study

Biophysical journal, 2023-02, Vol.122 (3), p.249a-249a

2023

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A Novel Approach to Detect Electrogenic Transporter Activity in Intact Cells Applied to Investigate IPSC Derived Cardiomyocytes and Neurons

Biophysical journal, 2020-02, Vol.118 (3), p.129a-130a

2020

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Kinetic and Pharmacological Properties of P2X3 and P2X2/3 Receptors

Biophysical journal, 2020-02, Vol.118 (3), p.118a-119a

2020

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Activation and Inhibition of Assay-Ready TRPA1 and TRPV Cells: An Automated Patch Clamp Study

Biophysical journal, 2021-02, Vol.120 (3), p.336a-336a

2021

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Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (30), p.12313-12318

2011

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An update on the advancing high-throughput screening techniques for patch clamp-based ion channel screens: implications for drug discovery

Expert opinion on drug discovery, 2018-03, Vol.13 (3), p.269-277

2018

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Oncogenic potential of EAG K+ channels

The EMBO journal, 1999-10, Vol.18 (20), p.5540-5547

1999

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Na+/Ca2+ Exchanger in Human iPSC Derived Cardiomyocytes: Functional Evidence and Relevance for Beating Behavior

Biophysical journal, 2019-02, Vol.116 (3), p.554a-554a

2019

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Combining Physiological Relevance and Throughput for in vitro Cardiac Contractility Measurement

Biophysical journal, 2020-02, Vol.118 (3), p.570a-570a

2020

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Membrane assembly of the functional KcsA potassium channel in a vesicle-based eukaryotic cell-free translation system

Biosensors & bioelectronics, 2014-09, Vol.59, p.174-183

2014

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Microchip Technology for Automated and Parallel Patch-Clamp Recording

Small (Weinheim an der Bergstrasse, Germany), 2006-07, Vol.2 (7), p.840-846

2006

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Characterizing human ion channels in induced pluripotent stem cell-derived neurons

Journal of biomolecular screening, 2012-10, Vol.17 (9), p.1264-1272

2012

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Planar patch clamp approach to characterize ionic currents from intact lysosomes

Science signaling, 2010-12, Vol.3 (151), p.pl3

2010

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Next level toxicity screening: From single channel to overall cell behavior

Toxicon (Oxford), 2018-07, Vol.149, p.87-87

2018

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Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module

Journal of Laboratory Automation, 2016-12, Vol.21 (6), p.779-793

2016

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Port-a-patch and patchliner: high fidelity electrophysiology for secondary screening and safety pharmacology

Automated patch clamp in drug discovery: major breakthroughs and innovation in the last decade

KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury

Accessing intracellular membrane transport proteins: a novel electrophysiological approach for lysosomal and mitochondrial channels and transporters

Mechanical activation of PIEZO1 channels using high throughput electrophysiology

Drug Effects On Human Na(+)/Ca(2+)Exchanger and Implications for Drug Development

Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca2+ Currents in Isolated Lysosomes

Mechanical and pharmacological activation of PIEZO1 channels characterized by high throughput electrophysiology

A Novel Gain of Function Mutation of Piezo-1 is Investigated in Red Blood Cells by High-Throughput Patch Clamp

Novel small-molecule modulation of PIEZO1 investigated by conventional and automated patch-clamp

Pharmacology of P2X3 and P2X2/3 receptors: An automated patch clamp study

A Novel Approach to Detect Electrogenic Transporter Activity in Intact Cells Applied to Investigate IPSC Derived Cardiomyocytes and Neurons

Kinetic and Pharmacological Properties of P2X3 and P2X2/3 Receptors

Activation and Inhibition of Assay-Ready TRPA1 and TRPV Cells: An Automated Patch Clamp Study

Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins

An update on the advancing high-throughput screening techniques for patch clamp-based ion channel screens: implications for drug discovery

Oncogenic potential of EAG K+ channels

Na+/Ca2+ Exchanger in Human iPSC Derived Cardiomyocytes: Functional Evidence and Relevance for Beating Behavior

Combining Physiological Relevance and Throughput for in vitro Cardiac Contractility Measurement

Membrane assembly of the functional KcsA potassium channel in a vesicle-based eukaryotic cell-free translation system

Microchip Technology for Automated and Parallel Patch-Clamp Recording

Characterizing human ion channels in induced pluripotent stem cell-derived neurons

Planar patch clamp approach to characterize ionic currents from intact lysosomes

Next level toxicity screening: From single channel to overall cell behavior

Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module

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