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Microphysiological lung models to evaluate the safety of new pharmaceutical modalities: a biopharmaceutical perspective

Lab on a chip, 2019-09, Vol.19 (19), p.3152-3161

2019

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Succinic semialdehyde dehydrogenase deficiency (SSADHD): Pathophysiological complexity and multifactorial trait associations in a rare monogenic disorder of GABA metabolism

Neurochemistry international, 2016-10, Vol.99, p.72-84

2016

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Succinic semialdehyde dehydrogenase deficiency, a disorder of GABA metabolism: an update on pharmacological and enzyme-replacement therapeutic strategies

Journal of inherited metabolic disease, 2018-07, Vol.41 (4), p.699-708

2018

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Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis

Toxicological sciences, 2013-03, Vol.132 (1), p.53-63

2013

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In vitro modeling of experimental succinic semialdehyde dehydrogenase deficiency (SSADHD) using brain-derived neural stem cells

PloS one, 2017-10, Vol.12 (10), p.e0186919-e0186919

2017

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mTOR Inhibition Mitigates Molecular and Biochemical Alterations of Vigabatrin-Induced Visual Field Toxicity in Mice

Pediatric neurology, 2017-01, Vol.66, p.44-52.e1

2017

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Aberrant mTOR signaling and disrupted autophagy: The missing link in potential vigabatrin‐associated ocular toxicity?

Clinical pharmacology and therapeutics, 2017-04, Vol.101 (4), p.458-461

2017

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Toxicologic/transport properties of NCS-382, a γ-hydroxybutyrate (GHB) receptor ligand, in neuronal and epithelial cells: Therapeutic implications for SSADH deficiency, a GABA metabolic disorder

Toxicology in vitro, 2018-02, Vol.46, p.203-212

2018

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Does the efficacy of neurodynamic treatments depend on the presence and type of criteria used to define neural mechanosensitivity in spinally-referred leg pain? A systematic review and meta-analysis

The South African journal of physiotherapy, 2022, Vol.78 (1), p.1627-1627

2022

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Comparison of boiling and chlorination on the quality of stored drinking water and childhood diarrhoea in Indonesian households

Epidemiology and infection, 2017-11, Vol.145 (15), p.3294-3302

2017

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In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of γ-hydroxybutyrate (GHB) binding

Toxicology in vitro, 2017-04, Vol.40, p.196-202

2017

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mTOR inhibitors rescue premature lethality and attenuate dysregulation of GABAergic/glutamatergic transcription in murine succinate semialdehyde dehydrogenase deficiency (SSADHD), a disorder of GABA metabolism

Journal of inherited metabolic disease, 2016-11, Vol.39 (6), p.877-886

2016

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Physiological competition of brain phenylalanine accretion: Initial pharmacokinetic analyses of aminoisobutyric and methylaminoisobutyric acids in Pahenu2−/− mice

Molecular genetics and metabolism reports, 2015-06, Vol.3 (C), p.80-87

2015

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Labeled content of two furanocoumarins in dietary supplements correlates with neither actual content nor CYP3A inhibitory activity

Journal of pharmaceutical and biomedical analysis, 2014-09, Vol.98, p.260-265

2014

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A pharmacokinetic evaluation and metabolite identification of the GHB receptor antagonist NCS‐382 in mouse informs novel therapeutic strategies for the treatment of GHB intoxication

Pharmacology research & perspectives, 2016-12, Vol.4 (6), p.e00265-n/a

2016

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Targeted screening of succinic semialdehyde dehydrogenase deficiency (SSADHD) employing an enzymatic assay for γ-hydroxybutyric acid (GHB) in biofluids

Molecular genetics and metabolism reports, 2017-06, Vol.11 (C), p.81-89

2017

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Torin 1 partially corrects vigabatrin‐induced mitochondrial increase in mouse

Annals of clinical and translational neurology, 2015-06, Vol.2 (6), p.699-706

2015

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Condicionan el crecimiento previo y el tamaño del árbol el decaimiento inducido por sequía en dos especies de Quercus?

Ecosistemas revista científica y técnica de ecología y medio ambiente, 2014-05, Vol.23 (2), p.73-81

2014

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Gamma-Hydroxybutyrate (GHB) Content in Hair Samples Correlates Negatively with Age in Succinic Semialdehyde Dehydrogenase Deficiency

JIMD Reports, Volume 36, 2017-01, Vol.36, p.93-98

2017

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Novel Molecular Markers in Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD), an Orphan Disorder of GABA Metabolism

The FASEB journal, 2018-04, Vol.32 (S1), p.818.18-818.18

2018

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Toxicologic/transport properties of NCS-382, a ?-hydroxybutyrate (GHB) receptor ligand, in neuronal and epithelial cells: Therapeutic implications for SSADH deficiency, a GABA metabolic disorder

Toxicology in vitro, 2018-02, Vol.46, p.203

2018

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WHAT MAKES A MALARIA HOTSPOT A HOTSPOT? EXAMPLE FROM ZANZIBAR

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2015, Vol.93 (4), p.199

2015

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In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of ?-hydroxybutyrate (GHB) binding

Toxicology in vitro, 2017-04, Vol.40, p.196

2017

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Quantification of Quadriceps Passive Resistance Using Isokinetic Dynamometry

Physiotherapy, 1996, Vol.82 (11), p.628-630

1996

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Physiological Competition of Brain Phenylalanine Accretion: Initial Pharmacokinetic Analyses of Aminoisobutyric and Methylaminoisobutyric Acids in Pah enu2-/- Mice

Molecular genetics and metabolism reports, 2015-06, Vol.3, p.80

2015

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Microphysiological lung models to evaluate the safety of new pharmaceutical modalities: a biopharmaceutical perspective

Succinic semialdehyde dehydrogenase deficiency (SSADHD): Pathophysiological complexity and multifactorial trait associations in a rare monogenic disorder of GABA metabolism

Succinic semialdehyde dehydrogenase deficiency, a disorder of GABA metabolism: an update on pharmacological and enzyme-replacement therapeutic strategies

Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis

In vitro modeling of experimental succinic semialdehyde dehydrogenase deficiency (SSADHD) using brain-derived neural stem cells

mTOR Inhibition Mitigates Molecular and Biochemical Alterations of Vigabatrin-Induced Visual Field Toxicity in Mice

Aberrant mTOR signaling and disrupted autophagy: The missing link in potential vigabatrin‐associated ocular toxicity?

Toxicologic/transport properties of NCS-382, a γ-hydroxybutyrate (GHB) receptor ligand, in neuronal and epithelial cells: Therapeutic implications for SSADH deficiency, a GABA metabolic disorder

Does the efficacy of neurodynamic treatments depend on the presence and type of criteria used to define neural mechanosensitivity in spinally-referred leg pain? A systematic review and meta-analysis

Comparison of boiling and chlorination on the quality of stored drinking water and childhood diarrhoea in Indonesian households

In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of γ-hydroxybutyrate (GHB) binding

mTOR inhibitors rescue premature lethality and attenuate dysregulation of GABAergic/glutamatergic transcription in murine succinate semialdehyde dehydrogenase deficiency (SSADHD), a disorder of GABA metabolism

Physiological competition of brain phenylalanine accretion: Initial pharmacokinetic analyses of aminoisobutyric and methylaminoisobutyric acids in Pahenu2−/− mice

Labeled content of two furanocoumarins in dietary supplements correlates with neither actual content nor CYP3A inhibitory activity

A pharmacokinetic evaluation and metabolite identification of the GHB receptor antagonist NCS‐382 in mouse informs novel therapeutic strategies for the treatment of GHB intoxication

Targeted screening of succinic semialdehyde dehydrogenase deficiency (SSADHD) employing an enzymatic assay for γ-hydroxybutyric acid (GHB) in biofluids

Torin 1 partially corrects vigabatrin‐induced mitochondrial increase in mouse

Condicionan el crecimiento previo y el tamaño del árbol el decaimiento inducido por sequía en dos especies de Quercus?

Gamma-Hydroxybutyrate (GHB) Content in Hair Samples Correlates Negatively with Age in Succinic Semialdehyde Dehydrogenase Deficiency

Novel Molecular Markers in Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD), an Orphan Disorder of GABA Metabolism

Toxicologic/transport properties of NCS-382, a ?-hydroxybutyrate (GHB) receptor ligand, in neuronal and epithelial cells: Therapeutic implications for SSADH deficiency, a GABA metabolic disorder

WHAT MAKES A MALARIA HOTSPOT A HOTSPOT? EXAMPLE FROM ZANZIBAR

In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of ?-hydroxybutyrate (GHB) binding

Quantification of Quadriceps Passive Resistance Using Isokinetic Dynamometry

Physiological Competition of Brain Phenylalanine Accretion: Initial Pharmacokinetic Analyses of Aminoisobutyric and Methylaminoisobutyric Acids in Pah enu2-/- Mice

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