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Which breast cancer decisions remain non-compliant with guidelines despite the use of computerised decision support?

British journal of cancer, 2013-09, Vol.109 (5), p.1147-1156

2013

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Role of modelling and simulation in Phase I drug development

European journal of pharmaceutical sciences, 2001-05, Vol.13 (2), p.115-122

2001

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Development and implementation of the population Fisher information matrix for the evaluation of population pharmacokinetic designs

Computer methods and programs in biomedicine, 2001-05, Vol.65 (2), p.141-151

2001

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The ISoP Standards and Best Practices Committee

Clinical pharmacology and therapeutics, 2014-06, Vol.95 (6), p.581-582

2014

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Pharmacokinetic Similarity of Biologics: Analysis Using Nonlinear Mixed-Effects Modeling

Clinical pharmacology and therapeutics, 2012-02, Vol.91 (2), p.234-242

2012

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Overview of model‐building strategies in population PK/PD analyses: 2002–2004 literature survey

British journal of clinical pharmacology, 2007-11, Vol.64 (5), p.603-612

2007

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Optimal design of a population pharmacodynamic experiment for ivabradine

Pharmaceutical research, 2001, Vol.18 (1), p.83-89

2001

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Comparison of lithium concentrations in red blood cells and plasma in samples collected for TDM, acute toxicity, or acute-on-chronic toxicity

European journal of clinical pharmacology, 2003-11, Vol.59 (8-9), p.583-587

2003

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Modelling and simulation in the development and use of anti-cancer agents : An underused tool?

Journal of pharmacokinetics and pharmacodynamics, 2004-12, Vol.31 (6), p.419-440

2004

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Fisher information matrix for non-linear mixed-effects models: evaluation and application for optimal design of enoxaparin population pharmacokinetics

Statistics in medicine, 2002-09, Vol.21 (18), p.2623-2639

2002

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Robust optimal design for the estimation of hyperparameters in population pharmacokinetics

Journal of pharmacokinetics and biopharmaceutics, 1998-12, Vol.26 (6), p.689-716

1998

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Population pharmacokinetic-pharmacodynamic analysis of fluindione in patients

Clinical pharmacology and therapeutics, 1998-01, Vol.63 (1), p.64-78

1998

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Cerebral uptake of mefloquine enantiomers with and without the P‐gp inhibitor elacridar (GF1210918) in mice

British journal of pharmacology, 2004-04, Vol.141 (7), p.1214-1222

2004

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Evolution of Human Immunodeficiency Virus Type 1 (HIV-1) Resistance Mutations in Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) in HIV-1-Infected Patients Switched to Antiretroviral Therapy without NNRTIs

Antimicrobial Agents and Chemotherapy, 2004-01, Vol.48 (1), p.172-175

2004

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Non-linear mixed effects modeling : From methodology and software development to driving implementation in drug development science

Journal of pharmacokinetics and pharmacodynamics, 2005-04, Vol.32 (2), p.161-183

2005

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Prediction of fluindione maintenance dosage hampered by large intraindividual variability

Therapeutic drug monitoring, 2000-12, Vol.22 (6), p.668-675

2000

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Optimization of individual and population designs using Splus

Journal of pharmacokinetics and pharmacodynamics, 2003-12, Vol.30 (6), p.417-443

2003

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Stochastic optimization algorithms of a Bayesian design criterion for Bayesian parameter estimation of nonlinear regression models: Application in pharmacokinetics

Mathematical biosciences, 1997-08, Vol.144 (1), p.45-70

1997

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Modeling INR data to predict maintenance fluindione dosage

Therapeutic drug monitoring, 1998-12, Vol.20 (6), p.631-639

1998

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Population pharmacokinetic analysis of mizolastine and validation from sparse data on patients using the nonparametric maximum likelihood method

Journal of pharmacokinetics and biopharmaceutics, 1998-04, Vol.26 (2), p.133-161

1998

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Population kinetics and conditional assessment of the optimal dosage regimen using the P-PHARM software package

Anticancer research, 1994-11, Vol.14 (6A), p.2321

1994

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Pharmacokinetic analysis of mizolastine in healthy young volunteers after single oral and intravenous doses : Noncompartmental approach and compartmental modeling

Journal of Pharmacokinetics and Biopharmaceutics, 1997-04, Vol.25 (2), p.125-147

1997

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Effect of efflux inhibition on brain uptake of itraconazole in mice infected with Cryptococcus neoformans

Drug metabolism and disposition, 2003-03, Vol.31 (3), p.319-325

2003

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Sparse-Sampling Optimal Designs in Pharmacokinetics and Toxicokinetics

Drug information journal, 1995, Vol.29 (3), p.997-1019

1995

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The use of simulated annealing for finding optimal population designs

Computer methods and programs in biomedicine, 2002-07, Vol.69 (1), p.25-35

2002

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Which breast cancer decisions remain non-compliant with guidelines despite the use of computerised decision support?

Role of modelling and simulation in Phase I drug development

Development and implementation of the population Fisher information matrix for the evaluation of population pharmacokinetic designs

The ISoP Standards and Best Practices Committee

Pharmacokinetic Similarity of Biologics: Analysis Using Nonlinear Mixed-Effects Modeling

Overview of model‐building strategies in population PK/PD analyses: 2002–2004 literature survey

Optimal design of a population pharmacodynamic experiment for ivabradine

Comparison of lithium concentrations in red blood cells and plasma in samples collected for TDM, acute toxicity, or acute-on-chronic toxicity

Modelling and simulation in the development and use of anti-cancer agents : An underused tool?

Fisher information matrix for non-linear mixed-effects models: evaluation and application for optimal design of enoxaparin population pharmacokinetics

Robust optimal design for the estimation of hyperparameters in population pharmacokinetics

Population pharmacokinetic-pharmacodynamic analysis of fluindione in patients

Cerebral uptake of mefloquine enantiomers with and without the P‐gp inhibitor elacridar (GF1210918) in mice

Evolution of Human Immunodeficiency Virus Type 1 (HIV-1) Resistance Mutations in Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) in HIV-1-Infected Patients Switched to Antiretroviral Therapy without NNRTIs

Non-linear mixed effects modeling : From methodology and software development to driving implementation in drug development science

Prediction of fluindione maintenance dosage hampered by large intraindividual variability

Optimization of individual and population designs using Splus

Stochastic optimization algorithms of a Bayesian design criterion for Bayesian parameter estimation of nonlinear regression models: Application in pharmacokinetics

Modeling INR data to predict maintenance fluindione dosage

Population pharmacokinetic analysis of mizolastine and validation from sparse data on patients using the nonparametric maximum likelihood method

Population kinetics and conditional assessment of the optimal dosage regimen using the P-PHARM software package

Pharmacokinetic analysis of mizolastine in healthy young volunteers after single oral and intravenous doses : Noncompartmental approach and compartmental modeling

Effect of efflux inhibition on brain uptake of itraconazole in mice infected with Cryptococcus neoformans

Sparse-Sampling Optimal Designs in Pharmacokinetics and Toxicokinetics

The use of simulated annealing for finding optimal population designs

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