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Small-cell lung cancer: what we know, what we need to know and the path forward

Nature reviews. Cancer, 2017-12, Vol.17 (12), p.725

2017

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ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs

Cell reports (Cambridge), 2016-08, Vol.16 (5), p.1259-1272

2016

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Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers

International journal of cancer, 2006-01, Vol.118 (2), p.257-262

2006

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Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery

PloS one, 2009-07, Vol.4 (7), p.e6146-e6146

2009

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ZEB1 drives epithelial-to-mesenchymal transition in lung cancer

The Journal of clinical investigation, 2016-09, Vol.126 (9), p.3219-3235

2016

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Epidermal growth factor receptor inhibition in lung cancer: the evolving role of individualized therapy

Cancer and metastasis reviews, 2010-03, Vol.29 (1), p.37-48

Gazdar, Adi F.

2010

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Analysis of TP53 Mutation Status in Human Cancer Cell Lines: A Reassessment

Human mutation, 2014-06, Vol.35 (6), p.756-765

2014

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Malignant mesothelioma: Facts, Myths, and Hypotheses

Journal of cellular physiology, 2012-01, Vol.227 (1), p.44-58

2012

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Proportion of Never-Smoker Non-Small Cell Lung Cancer Patients at Three Diverse Institutions

JNCI : Journal of the National Cancer Institute, 2017-01, Vol.109 (7), p.djw295

2017

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ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (41), p.14788-14793

2014

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Lung Cancer Cell Lines as Tools for Biomedical Discovery and Research

JNCI : Journal of the National Cancer Institute, 2010-09, Vol.102 (17), p.1310-1321

2010

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Genomic deregulation of the E2F/Rb pathway leads to activation of the oncogene EZH2 in small cell lung cancer

PloS one, 2013-08, Vol.8 (8), p.e71670-e71670

2013

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Lung Cancer Signatures in Plasma Based on Proteome Profiling of Mouse Tumor Models

Cancer cell, 2011-09, Vol.20 (3), p.289-299

2011

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Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells

PloS one, 2009-10, Vol.4 (10), p.e7464-e7464

2009

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miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers

PloS one, 2012-06, Vol.7 (6), p.e39167-e39167

2012

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SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers

Nature communications, 2017-01, Vol.8 (1), p.14098-14098, Article 14098

2017

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Role of CPS1 in Cell Growth, Metabolism and Prognosis in LKB1-Inactivated Lung Adenocarcinoma

JNCI : Journal of the National Cancer Institute, 2017-03, Vol.109 (3), p.1

2017

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PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR

Cancer research (Chicago, Ill.), 2009-04, Vol.69 (8), p.3256-3261

2009

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Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer

Genes & development, 2016-06, Vol.30 (11), p.1289-1299

2016

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HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

Cancer cell, 2006-07, Vol.10 (1), p.25-38

2006

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DNA Repair and Survival in Lung Cancer — The Two Faces of Janus

The New England journal of medicine, 2007-02, Vol.356 (8), p.771-773

Gazdar, Adi F

2007

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A Translational View of the Molecular Pathogenesis of Lung Cancer

Journal of thoracic oncology, 2007-04, Vol.2 (4), p.327-343

2007

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Personalized Medicine and Inhibition of EGFR Signaling in Lung Cancer

The New England journal of medicine, 2009-09, Vol.361 (10), p.1018-1020

Gazdar, Adi F

2009

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Knockdown of oncogenic KRAS in non-small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy

Molecular cancer therapeutics, 2011-02, Vol.10 (2), p.336-346

2011

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Small-cell lung cancer: what we know, what we need to know and the path forward

ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs

Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers

Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer

Epidermal growth factor receptor inhibition in lung cancer: the evolving role of individualized therapy

Analysis of TP53 Mutation Status in Human Cancer Cell Lines: A Reassessment

Malignant mesothelioma: Facts, Myths, and Hypotheses

Proportion of Never-Smoker Non-Small Cell Lung Cancer Patients at Three Diverse Institutions

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers

Lung Cancer Cell Lines as Tools for Biomedical Discovery and Research

Genomic deregulation of the E2F/Rb pathway leads to activation of the oncogene EZH2 in small cell lung cancer

Lung Cancer Signatures in Plasma Based on Proteome Profiling of Mouse Tumor Models

Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells

miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers

SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers

Role of CPS1 in Cell Growth, Metabolism and Prognosis in LKB1-Inactivated Lung Adenocarcinoma

PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR

Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer

HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

DNA Repair and Survival in Lung Cancer — The Two Faces of Janus

A Translational View of the Molecular Pathogenesis of Lung Cancer

Personalized Medicine and Inhibition of EGFR Signaling in Lung Cancer

A biobank of small cell lung cancer CDX models elucidates inter- and intratumoral phenotypic heterogeneity

Knockdown of oncogenic KRAS in non-small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy

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