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New horizons in predictive toxicology: current status and application.

Wilson, Alan G. E

1, 2011

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Influence of Molecular Flexibility and Polar Surface Area Metrics on Oral Bioavailability in the Rat

Journal of medicinal chemistry, 2004-11, Vol.47 (24), p.6104-6107

2004

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Evaluation of the potential carcinogenicity and genetic toxicity to humans of the herbicide acetochlor

Human & experimental toxicology, 1996-09, Vol.15 (9), p.702-735

1996

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Development of a highthroughput yeast-based assay for detection of metabolically activated genotoxins

Mutation research, 2008-05, Vol.653 (1), p.63-69

2008

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A multiple in silico program approach for the prediction of mutagenicity from chemical structure

Mutation research, 2003-08, Vol.539 (1), p.77-89

2003

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Evaluation of a Physiologically‐Based Pharmacokinetic Approach for Simulating the First‐Time‐In‐Animal Study

Basic & clinical pharmacology & toxicology, 2005-03, Vol.96 (3), p.254-256

2005

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Role of predictive metabolism and toxicity modeling in drug discovery--a summary of some recent advancements

Current opinion in drug discovery & development, 2003-01, Vol.6 (1), p.123

2003

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Ethane Sulfonate Metabolite of Alachlor: Assessment of Oncogenic Potential Based on Metabolic and Mechanistic Considerations

Toxicological sciences, 2000-05, Vol.55 (1), p.36-43

2000

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An evaluation of the carcinogenic potential of the herbicide alachlor to man

Human & experimental toxicology, 1999-06, Vol.18 (6), p.363

1999

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Summary of Toxicology Studies with Butachlor

Journal of Pesticide Science, 2000, Vol.25 (1), p.75-83

2000

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Optimization of Cryopreservation Procedures for Rat and Human Hepatocytes

Xenobiotica, 1989, Vol.19 (5), p.489-498

1989

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A Physiologically Based Model for Gastrointestinal Absorption and Excretion of Chemicals Carried by Lipids

Risk analysis, 1993-10, Vol.13 (5), p.531-543

1993

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Clearance of recombinant tissue factor pathway inhibitor (TFPI) in rabbits

Thrombosis and haemostasis, 1992-07, Vol.68 (1), p.33-36

1992

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Mechanism of Thiazopyr-Induced Effects on Thyroid Hormone Homeostasis in Male Sprague–Dawley Rats

Toxicology and applied pharmacology, 1997-01, Vol.142 (1), p.133-142

1997

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Landau-Kleffners syndrom

Tidsskrift for den Norske Lægeforening, 2015, Vol.135 (22), p.2061-2064

2015

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Metabolism of alachlor by rat and mouse liver and nasal turbinate tissues

Drug metabolism and disposition, 1990-05, Vol.18 (3), p.373

1990

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A study of the mechanism of butachlor-associated gastric neoplasms in sprague-dawley rats

Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, 1995-05, Vol.47 (2), p.107-116

1995

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A Tiered Approach to Pharmacokinetic Studies

Environmental health perspectives, 1994-12, Vol.102 (suppl 11), p.5-11

1994

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Metabolism of alachlor by rat and monkey liver and nasal turbinate tissue

Drug metabolism and disposition, 1992-07, Vol.20 (4), p.616

1992

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Application of Direct Analytic and Storage Phosphor Techniques in Quantitating Whole-Body Autoradiography Data

Toxicology mechanisms and methods, 1995, Vol.5 (1), p.15-20

1995

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The Use of Pharmacokinetics as an Interpretive and Predictive Tool in Chemical Toxicology Testing and Risk Assessment: A Position Paper on the Appropriate Use of Pharmacokinetics in Chemical Toxicology

Regulatory toxicology and pharmacology, 1994-06, Vol.19 (3), p.317-337

1994

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Identity and pathogenesis of stomach tumors in Sprague-Dawley rats associated with the dietary administration of Butachlor

Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, 1995-05, Vol.47 (2), p.95-105

1995

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Alachlor Not Estrogenic

Environmental health perspectives, 1994-03, Vol.102 (3), p.256-257

1994

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Comments on Incorporating Mechanistic Data into Quantitative Risk Assessment

Risk analysis, 1991-12, Vol.11 (4), p.581-582

1991

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A tiered approach to pharmacokinetic studies

Environmental Health Perspectives [ENVIRON. HEALTH PERSPECT.]. Vol. 102, no. 11 Suppl. 1994, 1994, Vol.102, p.no. 11 Sul.-no. 11 Sul.

1994

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New horizons in predictive toxicology: current status and application.

Influence of Molecular Flexibility and Polar Surface Area Metrics on Oral Bioavailability in the Rat

Evaluation of the potential carcinogenicity and genetic toxicity to humans of the herbicide acetochlor

Development of a highthroughput yeast-based assay for detection of metabolically activated genotoxins

A multiple in silico program approach for the prediction of mutagenicity from chemical structure

Evaluation of a Physiologically‐Based Pharmacokinetic Approach for Simulating the First‐Time‐In‐Animal Study

Role of predictive metabolism and toxicity modeling in drug discovery--a summary of some recent advancements

Ethane Sulfonate Metabolite of Alachlor: Assessment of Oncogenic Potential Based on Metabolic and Mechanistic Considerations

An evaluation of the carcinogenic potential of the herbicide alachlor to man

Summary of Toxicology Studies with Butachlor

Optimization of Cryopreservation Procedures for Rat and Human Hepatocytes

A Physiologically Based Model for Gastrointestinal Absorption and Excretion of Chemicals Carried by Lipids

Clearance of recombinant tissue factor pathway inhibitor (TFPI) in rabbits

Mechanism of Thiazopyr-Induced Effects on Thyroid Hormone Homeostasis in Male Sprague–Dawley Rats

Landau-Kleffners syndrom

Metabolism of alachlor by rat and mouse liver and nasal turbinate tissues

A study of the mechanism of butachlor-associated gastric neoplasms in sprague-dawley rats

A Tiered Approach to Pharmacokinetic Studies

Metabolism of alachlor by rat and monkey liver and nasal turbinate tissue

Application of Direct Analytic and Storage Phosphor Techniques in Quantitating Whole-Body Autoradiography Data

The Use of Pharmacokinetics as an Interpretive and Predictive Tool in Chemical Toxicology Testing and Risk Assessment: A Position Paper on the Appropriate Use of Pharmacokinetics in Chemical Toxicology

Identity and pathogenesis of stomach tumors in Sprague-Dawley rats associated with the dietary administration of Butachlor

Alachlor Not Estrogenic

Comments on Incorporating Mechanistic Data into Quantitative Risk Assessment

A tiered approach to pharmacokinetic studies

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