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Adeno-Associated Virus Serotype 9 Vectors Transduce Murine Alveolar and Nasal Epithelia and Can Be Readministered

Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (35), p.12993-12998

2006

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Intranasal antibody gene transfer in mice and ferrets elicits broad protection against pandemic influenza

Science translational medicine, 2013-05, Vol.5 (187), p.187ra72

2013

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Adeno-associated virus-mediated expression of human butyrylcholinesterase to treat organophosphate poisoning

PloS one, 2019-11, Vol.14 (11), p.e0225188

2019

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Preclinical Development of a HIV-Based Gene Therapeutic for Cystic Fibrosis Pulmonary Disease

Human gene therapy, 2021-08, Vol.32 (15-16), p.862

Limberis, Maria P

2021

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Durable transgene expression and efficient re-administration after rAAV2.5T-mediated fCFTRΔR gene delivery to adult ferret lungs

Molecular therapy. Methods & clinical development, 2024-06, Vol.32 (2), p.101244-101244, Article 101244

2024

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Immunosuppression reduces rAAV2.5T neutralizing antibodies that limit efficacy following repeat dosing to ferret lungs

Molecular therapy. Methods & clinical development, 2023-06, Vol.29, p.70-80

2023

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Non-Clinical Study Examining AAV8.TBG.hLDLR Vector-Associated Toxicity in Chow-Fed Wild-Type and LDLR +/- Rhesus Macaques

Human gene therapy. Clinical development, 2017-03, Vol.28 (1), p.39

2017

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Nonclinical Pharmacology/Toxicology Study of AAV8.TBG.mLDLR and AAV8.TBG.hLDLR in a Mouse Model of Homozygous Familial Hypercholesterolemia

Human gene therapy. Clinical development, 2017-03, Vol.28 (1), p.28

2017

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Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6414), p.598-602

2018

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Adeno-Associated Virus Vector-Mediated Expression of Antirespiratory Syncytial Virus Antibody Prevents Infection in Mouse Airways

Human gene therapy, 2021-12, Vol.32 (23-24), p.1450

2021

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Intrathecal viral vector delivery of trastuzumab prevents or inhibits tumor growth of human HER2-positive xenografts in mice

Cancer research (Chicago, Ill.), 2018-11, Vol.78 (21), p.6171-6182

2018

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Adeno-Associated Virus Serotype 9-Expressed ZMapp in Mice Confers Protection Against Systemic and Airway-Acquired Ebola Virus Infection

The Journal of infectious diseases, 2016-12, Vol.214 (12), p.1975-1979

2016

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Optical imaging of Ca2+-evoked fluid secretion by murine nasal submucosal gland serous acinar cells

The Journal of physiology, 2007-08, Vol.582 (3), p.1099-1124

2007

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HCO3(-) secretion by murine nasal submucosal gland serous acinar cells during Ca2+-stimulated fluid secretion

The Journal of general physiology, 2008-07, Vol.132 (1), p.161-183

2008

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Human CRB1-associated retinal degeneration: comparison with the rd8 Crb1-mutant mouse model

Investigative ophthalmology & visual science, 2011-08, Vol.52 (9), p.6898-6910

2011

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Adeno-associated virus 9-mediated airway expression of antibody protects old and immunodeficient mice against influenza virus

Clinical and vaccine immunology, 2014-11, Vol.21 (11), p.1528-1533

2014

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RPGR-associated retinal degeneration in human X-linked RP and a murine model

Investigative ophthalmology & visual science, 2012-08, Vol.53 (9), p.5594-5608

2012

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In vivo evaluation of adeno-associated virus gene transfer in airways of mice with acute or chronic respiratory infection

Human gene therapy, 2014-11, Vol.25 (11), p.966

2014

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Vectored expression of the broadly neutralizing antibody FI6 in mouse airway provides partial protection against a new avian influenza A virus, H7N9

Clinical and vaccine immunology, 2013-12, Vol.20 (12), p.1836-1837

2013

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Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing

Human gene therapy, 2009-03, Vol.20 (3), p.267

2009

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Prediction of Cellular Immune Responses against CFTR in Patients with Cystic Fibrosis after Gene Therapy

American journal of respiratory cell and molecular biology, 2007-05, Vol.36 (5), p.529-533

2007

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Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia

Human gene therapy. Clinical development, 2013-12, Vol.24 (4), p.154

2013

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Human immunodeficiency viral vector pseudotyped with the spike envelope of severe acute respiratory syndrome coronavirus transduces human airway epithelial cells and dendritic cells

Human gene therapy, 2007-05, Vol.18 (5), p.413

2007

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α-Fetoprotein gene delivery to the nasal epithelium of nonhuman primates by human parainfluenza viral vectors

Human gene therapy, 2010-12, Vol.21 (12), p.1657

2010

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Evaluation of Virus‐based Vectors for Cystic Fibrosis Gene Therapy

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Adeno-Associated Virus Serotype 9 Vectors Transduce Murine Alveolar and Nasal Epithelia and Can Be Readministered

Intranasal antibody gene transfer in mice and ferrets elicits broad protection against pandemic influenza

Adeno-associated virus-mediated expression of human butyrylcholinesterase to treat organophosphate poisoning

Preclinical Development of a HIV-Based Gene Therapeutic for Cystic Fibrosis Pulmonary Disease

Durable transgene expression and efficient re-administration after rAAV2.5T-mediated fCFTRΔR gene delivery to adult ferret lungs

Immunosuppression reduces rAAV2.5T neutralizing antibodies that limit efficacy following repeat dosing to ferret lungs

Non-Clinical Study Examining AAV8.TBG.hLDLR Vector-Associated Toxicity in Chow-Fed Wild-Type and LDLR +/- Rhesus Macaques

Nonclinical Pharmacology/Toxicology Study of AAV8.TBG.mLDLR and AAV8.TBG.hLDLR in a Mouse Model of Homozygous Familial Hypercholesterolemia

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

Adeno-Associated Virus Vector-Mediated Expression of Antirespiratory Syncytial Virus Antibody Prevents Infection in Mouse Airways

Intrathecal viral vector delivery of trastuzumab prevents or inhibits tumor growth of human HER2-positive xenografts in mice

Adeno-Associated Virus Serotype 9-Expressed ZMapp in Mice Confers Protection Against Systemic and Airway-Acquired Ebola Virus Infection

Optical imaging of Ca2+-evoked fluid secretion by murine nasal submucosal gland serous acinar cells

HCO3(-) secretion by murine nasal submucosal gland serous acinar cells during Ca2+-stimulated fluid secretion

Human CRB1-associated retinal degeneration: comparison with the rd8 Crb1-mutant mouse model

Adeno-associated virus 9-mediated airway expression of antibody protects old and immunodeficient mice against influenza virus

RPGR-associated retinal degeneration in human X-linked RP and a murine model

In vivo evaluation of adeno-associated virus gene transfer in airways of mice with acute or chronic respiratory infection

Vectored expression of the broadly neutralizing antibody FI6 in mouse airway provides partial protection against a new avian influenza A virus, H7N9

Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing

Prediction of Cellular Immune Responses against CFTR in Patients with Cystic Fibrosis after Gene Therapy

Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia

Human immunodeficiency viral vector pseudotyped with the spike envelope of severe acute respiratory syndrome coronavirus transduces human airway epithelial cells and dendritic cells

α-Fetoprotein gene delivery to the nasal epithelium of nonhuman primates by human parainfluenza viral vectors

Evaluation of Virus‐based Vectors for Cystic Fibrosis Gene Therapy

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