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Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-12, Vol.844 (2), p.292-300

2006

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Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats

Toxicology and applied pharmacology, 2023-04, Vol.465, p.116454-116454, Article 116454

Earl Gray, L.

2023

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Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/HO-1 signaling

European journal of medicinal chemistry, 2022-11, Vol.242, p.114692, Article 114692

2022

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Inhibitory effects of a dietary phytochemical 3,3′-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats

Food and chemical toxicology, 2008-07, Vol.46 (7), p.2451-2458

2008

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Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells

Toxicology and applied pharmacology, 2004-09, Vol.199 (3), p.332-343

2004

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Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes

Toxicology letters, 2006-02, Vol.161 (1), p.61-72

2006

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Aryl hydrocarbon receptor agonists trigger avoidance of novel food in rats

Physiology & behavior, 2016-12, Vol.167, p.49-59

2016

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The Role of Cytochrome 2B1 Substrate Recognition Site Residues 115, 294, 297, 298, and 362 in the Oxidation of Steroids and 7-Alkoxycoumarins

Archives of biochemistry and biophysics, 2001-10, Vol.394 (1), p.21-28

2001

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Reduction of thyroid hormones triggers down-regulation of hepatic CYP2B through nuclear receptors CAR and TR in a rat model of acute stroke

Biochemical pharmacology, 2014-02, Vol.87 (4), p.636-649

2014

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A technical mixture of 2,2′,4,4′-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity

Chemosphere (Oxford), 2008-09, Vol.73 (2), p.209-215

2008

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Toxicological Consequences of Differential Regulation of Cytochrome P450 Isoforms in Rat Brain Regions by Phenobarbital

Archives of biochemistry and biophysics, 2002-03, Vol.399 (1), p.56-65

2002

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Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays

European journal of medicinal chemistry, 2010-11, Vol.45 (11), p.4845-4855

2010

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Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine

Archives of biochemistry and biophysics, 2004-03, Vol.423 (2), p.277-287

2004

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N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: Effects of cytochrome P450 induction by phenobarbital

Toxicology letters, 2011-10, Vol.206 (2), p.139-143

2011

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In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis

Regulatory toxicology and pharmacology, 2010-07, Vol.57 (2-3), p.129-135

2010

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Conformational Change and Activation of Cytochrome P450 2B1 Induced by Salt and Phospholipid

Archives of biochemistry and biophysics, 1998-08, Vol.356 (2), p.229-238

1998

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Green tea extract increases cyclophosphamide-induced teratogenesis by modulating the expression of cytochrome P-450 mRNA

Reproductive toxicology (Elmsford, N.Y.), 2009, Vol.27 (1), p.79-84

2009

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Overexpression of cerebral and hepatic cytochrome P450s alters behavioral activity of rat offspring following prenatal exposure to lindane

Toxicology and applied pharmacology, 2007-12, Vol.225 (3), p.278-292

2007

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Mechanistic Studies of Cytochrome P450 2B1 Inactivation by Xanthates

Archives of biochemistry and biophysics, 2000-06, Vol.378 (1), p.157-166

2000

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Role of the Alanine at Position 363 of Cytochrome P450 2B2 in Influencing the NADPH- and Hydroperoxide-Supported Activities

Archives of biochemistry and biophysics, 1998-02, Vol.350 (2), p.324-332

1998

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Piperine inhibits aflatoxin B1-induced cytotoxicity and genotoxicity in V79 Chinese hamster cells genetically engineered to express rat cytochrome P4502B1

Journal of ethnopharmacology, 1997-11, Vol.58 (3), p.165-173

1997

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Effect of several analogs of 2,4,6-triphenyldioxane-1,3 on constitutive androstane receptor activation

Chemico-biological interactions, 2011-07, Vol.192 (3), p.177-183

2011

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Docosahexaenoic acid down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes via the sphingomyelinase/ceramide pathway

The Journal of nutritional biochemistry, 2010-04, Vol.21 (4), p.338-344

2010

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DHA down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes by attenuating CAR translocation

Toxicology and applied pharmacology, 2007-12, Vol.225 (3), p.329-336

2007

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An in vitro study on 5-HT6 receptor antagonist induced hepatotoxicity based on biochemical assays and toxicogenomics

Toxicology in vitro, 2007-10, Vol.21 (7), p.1276-1286

2007

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Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats

Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/HO-1 signaling

Inhibitory effects of a dietary phytochemical 3,3′-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats

Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells

Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes

Aryl hydrocarbon receptor agonists trigger avoidance of novel food in rats

The Role of Cytochrome 2B1 Substrate Recognition Site Residues 115, 294, 297, 298, and 362 in the Oxidation of Steroids and 7-Alkoxycoumarins

Reduction of thyroid hormones triggers down-regulation of hepatic CYP2B through nuclear receptors CAR and TR in a rat model of acute stroke

A technical mixture of 2,2′,4,4′-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity

Toxicological Consequences of Differential Regulation of Cytochrome P450 Isoforms in Rat Brain Regions by Phenobarbital

Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays

Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine

N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: Effects of cytochrome P450 induction by phenobarbital

In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis

Conformational Change and Activation of Cytochrome P450 2B1 Induced by Salt and Phospholipid

Green tea extract increases cyclophosphamide-induced teratogenesis by modulating the expression of cytochrome P-450 mRNA

Overexpression of cerebral and hepatic cytochrome P450s alters behavioral activity of rat offspring following prenatal exposure to lindane

Mechanistic Studies of Cytochrome P450 2B1 Inactivation by Xanthates

Role of the Alanine at Position 363 of Cytochrome P450 2B2 in Influencing the NADPH- and Hydroperoxide-Supported Activities

Piperine inhibits aflatoxin B1-induced cytotoxicity and genotoxicity in V79 Chinese hamster cells genetically engineered to express rat cytochrome P4502B1

Effect of several analogs of 2,4,6-triphenyldioxane-1,3 on constitutive androstane receptor activation

Docosahexaenoic acid down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes via the sphingomyelinase/ceramide pathway

DHA down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes by attenuating CAR translocation

An in vitro study on 5-HT6 receptor antagonist induced hepatotoxicity based on biochemical assays and toxicogenomics

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