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Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-12, Vol.844 (2), p.292-300

2006

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Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/HO-1 signaling

European journal of medicinal chemistry, 2022-11, Vol.242, p.114692, Article 114692

2022

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Aryl hydrocarbon receptor agonists trigger avoidance of novel food in rats

Physiology & behavior, 2016-12, Vol.167, p.49-59

2016

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The Role of Cytochrome 2B1 Substrate Recognition Site Residues 115, 294, 297, 298, and 362 in the Oxidation of Steroids and 7-Alkoxycoumarins

Archives of biochemistry and biophysics, 2001-10, Vol.394 (1), p.21-28

2001

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Reduction of thyroid hormones triggers down-regulation of hepatic CYP2B through nuclear receptors CAR and TR in a rat model of acute stroke

Biochemical pharmacology, 2014-02, Vol.87 (4), p.636-649

2014

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Toxicological Consequences of Differential Regulation of Cytochrome P450 Isoforms in Rat Brain Regions by Phenobarbital

Archives of biochemistry and biophysics, 2002-03, Vol.399 (1), p.56-65

2002

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Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays

European journal of medicinal chemistry, 2010-11, Vol.45 (11), p.4845-4855

2010

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Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine

Archives of biochemistry and biophysics, 2004-03, Vol.423 (2), p.277-287

2004

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Conformational Change and Activation of Cytochrome P450 2B1 Induced by Salt and Phospholipid

Archives of biochemistry and biophysics, 1998-08, Vol.356 (2), p.229-238

1998

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Mechanistic Studies of Cytochrome P450 2B1 Inactivation by Xanthates

Archives of biochemistry and biophysics, 2000-06, Vol.378 (1), p.157-166

2000

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Role of the Alanine at Position 363 of Cytochrome P450 2B2 in Influencing the NADPH- and Hydroperoxide-Supported Activities

Archives of biochemistry and biophysics, 1998-02, Vol.350 (2), p.324-332

1998

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Piperine inhibits aflatoxin B1-induced cytotoxicity and genotoxicity in V79 Chinese hamster cells genetically engineered to express rat cytochrome P4502B1

Journal of ethnopharmacology, 1997-11, Vol.58 (3), p.165-173

1997

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Docosahexaenoic acid down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes via the sphingomyelinase/ceramide pathway

The Journal of nutritional biochemistry, 2010-04, Vol.21 (4), p.338-344

2010

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Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats

The Science of the total environment, 2018-06, Vol.625, p.657-666

2018

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Proteolytic Degradation of Heme-Modified Hepatic Cytochromes P450: A Role for Phosphorylation, Ubiquitination, and the 26S Proteasome?

Archives of biochemistry and biophysics, 1999-05, Vol.365 (1), p.31-44

1999

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Epitope Mapping of Rat Cytochrome P450 2B1 Using Glutathione S-Transferase-2B1 Fusion Constructs

Archives of biochemistry and biophysics, 2000-08, Vol.380 (1), p.117-125

2000

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Effects of epidermal growth factor on CYP inducibility by xenobiotics, DNA replication, and caspase activations in collagen I gel sandwich cultures of rat hepatocytes

Biochemical pharmacology, 2001-05, Vol.61 (10), p.1293-1303

2001

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Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: Correlation study with induction in vivo

Journal of pharmacological and toxicological methods, 2005-09, Vol.52 (2), p.234-243

2005

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Compound danshen dripping pills affect the pharmacokinetics of azisartan by regulating the expression of cytochrome P450 2B1, 2C6, and 2C11 in rats

Journal of pharmaceutical and biomedical analysis, 2021-02, Vol.195, p.113887, Article 113887

2021

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Comparison of substrate metabolism by cytochromes P450 2B1, 2B4, and 2B6: relationship of heme spin state, catalysis, and the effects of cytochrome b5

Journal of inorganic biochemistry, 2003-01, Vol.93 (3), p.152-160

2003

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Expression of microRNAs, CYP1A1 and CYP2B1 in the livers and ovaries of female rats treated with DDT and PAHs

Life sciences (1973), 2014-05, Vol.103 (2), p.95-100

2014

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Impaired nuclear translocation of CAR in hepatic preneoplastic lesions: Association with an attenuated CYP2B induction by phenobarbital

FEBS letters, 2005-07, Vol.579 (17), p.3560-3564

2005

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Molecular probes of the mechanism of cytochrome P450. Oxygen traps a substrate radical intermediate

Archives of biochemistry and biophysics, 2011-03, Vol.507 (1), p.111-118

2011

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The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics

European neuropsychopharmacology, 2002-10, Vol.12 (5), p.371-377

2002

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Microsomal cytochromes P450 catalyze the oxidation of low density lipoprotein

Atherosclerosis, 1999-04, Vol.143 (2), p.253-260

1999

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Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/HO-1 signaling

Aryl hydrocarbon receptor agonists trigger avoidance of novel food in rats

The Role of Cytochrome 2B1 Substrate Recognition Site Residues 115, 294, 297, 298, and 362 in the Oxidation of Steroids and 7-Alkoxycoumarins

Reduction of thyroid hormones triggers down-regulation of hepatic CYP2B through nuclear receptors CAR and TR in a rat model of acute stroke

Toxicological Consequences of Differential Regulation of Cytochrome P450 Isoforms in Rat Brain Regions by Phenobarbital

Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays

Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine

Conformational Change and Activation of Cytochrome P450 2B1 Induced by Salt and Phospholipid

Mechanistic Studies of Cytochrome P450 2B1 Inactivation by Xanthates

Role of the Alanine at Position 363 of Cytochrome P450 2B2 in Influencing the NADPH- and Hydroperoxide-Supported Activities

Piperine inhibits aflatoxin B1-induced cytotoxicity and genotoxicity in V79 Chinese hamster cells genetically engineered to express rat cytochrome P4502B1

Docosahexaenoic acid down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes via the sphingomyelinase/ceramide pathway

Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats

Proteolytic Degradation of Heme-Modified Hepatic Cytochromes P450: A Role for Phosphorylation, Ubiquitination, and the 26S Proteasome?

Epitope Mapping of Rat Cytochrome P450 2B1 Using Glutathione S-Transferase-2B1 Fusion Constructs

Effects of epidermal growth factor on CYP inducibility by xenobiotics, DNA replication, and caspase activations in collagen I gel sandwich cultures of rat hepatocytes

Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: Correlation study with induction in vivo

Compound danshen dripping pills affect the pharmacokinetics of azisartan by regulating the expression of cytochrome P450 2B1, 2C6, and 2C11 in rats

Comparison of substrate metabolism by cytochromes P450 2B1, 2B4, and 2B6: relationship of heme spin state, catalysis, and the effects of cytochrome b5

Expression of microRNAs, CYP1A1 and CYP2B1 in the livers and ovaries of female rats treated with DDT and PAHs

Impaired nuclear translocation of CAR in hepatic preneoplastic lesions: Association with an attenuated CYP2B induction by phenobarbital

Molecular probes of the mechanism of cytochrome P450. Oxygen traps a substrate radical intermediate

The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics

Microsomal cytochromes P450 catalyze the oxidation of low density lipoprotein

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