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Lipocalin 2: An Emerging Player in Iron Homeostasis and Inflammation

Annual review of nutrition, 2017-08, Vol.37 (1), p.103-130

2017

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Lipocalin-2 counteracts metabolic dysregulation in obesity and diabetes

The Journal of experimental medicine, 2020-10, Vol.217 (10)

2020

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Machine learning guided aptamer refinement and discovery

Nature communications, 2021-04, Vol.12 (1), p.2366-2366, Article 2366

2021

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Siderophores in Iron Metabolism: From Mechanism to Therapy Potential

Trends in molecular medicine, 2016-12, Vol.22 (12), p.1077-1090

2016

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A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

Nature communications, 2021-12, Vol.12 (1), p.7333-17, Article 7333

2021

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Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation

Trends in endocrinology and metabolism, 2017-05, Vol.28 (5), p.388-397

2017

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Lipocalin-2 protects the brain during inflammatory conditions

Molecular psychiatry, 2018-02, Vol.23 (2), p.344-350

2018

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NUPR1 is a critical repressor of ferroptosis

Nature communications, 2021-01, Vol.12 (1), p.647-647, Article 647

2021

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Gene interfered-ferroptosis therapy for cancers

Nature communications, 2021-09, Vol.12 (1), p.5311-16, Article 5311

2021

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Astrocyte‐derived lipocalin‐2 mediates hippocampal damage and cognitive deficits in experimental models of vascular dementia

Glia, 2017-09, Vol.65 (9), p.1471-1490

2017

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The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction

American journal of physiology. Renal physiology, 2021-04, Vol.320 (4), p.F608-F616

2021

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MC4R-dependent suppression of appetite by bone-derived lipocalin 2

Nature (London), 2017-03, Vol.543 (7645), p.385-390

2017

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Astrocytic phagocytosis contributes to demyelination after focal cortical ischemia in mice

Nature communications, 2022-03, Vol.13 (1), p.1134-1134, Article 1134

2022

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C/EBPδ Mediates Immunity to Renal Autoinflammatory Disorders in a Stage-specific Manner

The Journal of immunology (1950), 2024-09, Vol.213 (6), p.767-778

2024

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TNFα-induced NLRP3 inflammasome mediates adipocyte dysfunction and activates macrophages through adipocyte-derived lipocalin 2

Metabolism, clinical and experimental, 2023-05, Vol.142, p.155527-155527, Article 155527

2023

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Increased neutrophil gelatinase-associated lipocalin (NGAL) promotes airway remodelling in chronic obstructive pulmonary disease

Clinical science (1979), 2017-06, Vol.131 (11), p.1147-1159

2017

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Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage

Autophagy, 2023-08, Vol.19 (8), p.2296-2317

2023

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Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment

Cancer research (Chicago, Ill.), 2017-05, Vol.77 (10), p.2647-2660

2017

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Lipocalin‐2 (NGAL) Attenuates Autophagy to Exacerbate Cardiac Apoptosis Induced by Myocardial Ischemia

Journal of cellular physiology, 2017-08, Vol.232 (8), p.2125-2134

2017

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Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice

Cardiovascular research, 2016-08, Vol.111 (3), p.262-273

2016

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PGC‐1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI

The Journal of pathology, 2019-09, Vol.249 (1), p.65-78

2019

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NGAL as a Potential Target in Tumor Microenvironment

International journal of molecular sciences, 2021-11, Vol.22 (22), p.12333

2021

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Neutrophil Gelatinase-Associated Lipocalin From Macrophages Plays a Critical Role in Renal Fibrosis Via the CCL5 (Chemokine Ligand 5)-Th2 Cells-IL4 (Interleukin 4) Pathway

Hypertension (Dallas, Tex. 1979), 2022-02, Vol.79 (2), p.352-364

2022

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Biological Functions and Therapeutic Potential of Lipocalin 2 in Cancer

International journal of molecular sciences, 2020-06, Vol.21 (12), p.4365

2020

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Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung

Nature communications, 2021-01, Vol.12 (1), p.474-18, Article 474

2021

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Lipocalin 2: An Emerging Player in Iron Homeostasis and Inflammation

Lipocalin-2 counteracts metabolic dysregulation in obesity and diabetes

Machine learning guided aptamer refinement and discovery

Siderophores in Iron Metabolism: From Mechanism to Therapy Potential

A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation

Lipocalin-2 protects the brain during inflammatory conditions

NUPR1 is a critical repressor of ferroptosis

Gene interfered-ferroptosis therapy for cancers

Astrocyte‐derived lipocalin‐2 mediates hippocampal damage and cognitive deficits in experimental models of vascular dementia

The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction

MC4R-dependent suppression of appetite by bone-derived lipocalin 2

Astrocytic phagocytosis contributes to demyelination after focal cortical ischemia in mice

C/EBPδ Mediates Immunity to Renal Autoinflammatory Disorders in a Stage-specific Manner

TNFα-induced NLRP3 inflammasome mediates adipocyte dysfunction and activates macrophages through adipocyte-derived lipocalin 2

Increased neutrophil gelatinase-associated lipocalin (NGAL) promotes airway remodelling in chronic obstructive pulmonary disease

Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage

Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment

Lipocalin‐2 (NGAL) Attenuates Autophagy to Exacerbate Cardiac Apoptosis Induced by Myocardial Ischemia

Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice

PGC‐1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI

NGAL as a Potential Target in Tumor Microenvironment

Neutrophil Gelatinase-Associated Lipocalin From Macrophages Plays a Critical Role in Renal Fibrosis Via the CCL5 (Chemokine Ligand 5)-Th2 Cells-IL4 (Interleukin 4) Pathway

Biological Functions and Therapeutic Potential of Lipocalin 2 in Cancer

Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung

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