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Chronic Visceral Pain: New Peripheral Mechanistic Insights and Resulting Treatments

Gastroenterology (New York, N.Y. 1943), 2024-06, Vol.166 (6), p.976-994

2024

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Gut enterochromaffin cells drive visceral pain and anxiety

Nature (London), 2023-04, Vol.616 (7955), p.137-142

2023

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Regional neuroplastic brain changes in patients with chronic inflammatory and non-inflammatory visceral pain

PloS one, 2014-01, Vol.9 (1), p.e84564-e84564

2014

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IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain

Science (American Association for the Advancement of Science), 2019-07, Vol.365 (6450)

2019

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Effect of electroacupuncture on P2X3 receptor regulation in the peripheral and central nervous systems of rats with visceral pain caused by irritable bowel syndrome

Purinergic signalling, 2015-09, Vol.11 (3), p.321-329

2015

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Common and distinct neural representations of aversive somatic and visceral stimulation in healthy individuals

Nature communications, 2020-11, Vol.11 (1), p.5939-5939, Article 5939

2020

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NaV1.1 inhibition can reduce visceral hypersensitivity

JCI insight, 2018-06, Vol.3 (11)

2018

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Enhanced spinal neuronal responses as a mechanism for increased number and size of active acupoints in visceral hyperalgesia

Scientific reports, 2020-06, Vol.10 (1), p.10312-11, Article 10312

2020

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Oral treatment with plecanatide or dolcanatide attenuates visceral hypersensitivity via activation of guanylate cyclase-C in rat models

World journal of gastroenterology : WJG, 2018-05, Vol.24 (17), p.1888-1900

2018

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Probiotics VSL#3 protect against development of visceral pain in murine model of irritable bowel syndrome

PloS one, 2013-05, Vol.8 (5), p.e63893-e63893

2013

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Gabapentin Effects on PKC-ERK1/2 Signaling in the Spinal Cord of Rats with Formalin-Induced Visceral Inflammatory Pain

PloS one, 2015-10, Vol.10 (10), p.e0141142-e0141142

2015

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Zeta Inhibitory Peptide as a Novel Therapy to Control Chronic Visceral Hypersensitivity in a Rat Model

PloS one, 2016-10, Vol.11 (10), p.e0163324-e0163324

2016

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Visceral and somatic pain modalities reveal Na V 1.7-independent visceral nociceptive pathways

The Journal of physiology, 2017-04, Vol.595 (8), p.2661-2679

2017

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The voltage-gated sodium channel NaV 1.9 in visceral pain

Neurogastroenterology and motility, 2016-03, Vol.28 (3), p.316-326

2016

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5-HT 3 receptor signaling in serotonin transporter-knockout rats: a female sex-specific animal model of visceral hypersensitivity

American journal of physiology: Gastrointestinal and liver physiology, 2019-01, Vol.316 (1), p.G132-G143

2019

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Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner

PloS one, 2015-12, Vol.10 (12), p.e0145556-e0145556

2015

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Colitis-Induced Microbial Perturbation Promotes Postinflammatory Visceral Hypersensitivity

Cellular and molecular gastroenterology and hepatology, 2020-01, Vol.10 (2), p.225-244

2020

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Ameliorative effect of chlorpromazine hydrochloride on visceral hypersensitivity in rats: possible involvement of 5-HT 2A receptor

British journal of pharmacology, 2017-10, Vol.174 (19), p.3370-3381

2017

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Parasympathetic activity correlates with subjective and brain responses to rectal distension in healthy subjects but not in non-constipated patients with irritable bowel syndrome

Scientific reports, 2019-05, Vol.9 (1), p.7358, Article 7358

2019

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Differential Activation in Amygdala and Plasma Noradrenaline during Colorectal Distention by Administration of Corticotropin-Releasing Hormone between Healthy Individuals and Patients with Irritable Bowel Syndrome

PloS one, 2016-07, Vol.11 (7), p.e0157347-e0157347

2016

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How positive and negative expectations shape the experience of visceral pain

Handbook of experimental pharmacology, 2014, Vol.225, p.97

Elsenbruch, Sigrid

2014

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Colonic overexpression of the T-type calcium channel Ca v 3.2 in a mouse model of visceral hypersensitivity and in irritable bowel syndrome patients

Neurogastroenterology and motility, 2016-11, Vol.28 (11), p.1632-1640

2016

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Nalbuphine alleviates inflammation by down-regulating NF-κB in an acute inflammatory visceral pain rat model

BMC pharmacology & toxicology, 2022-06, Vol.23 (1), p.34-34, Article 34

2022

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MicroRNA-based therapy in pain medicine: Current progress and future prospects

Acta anaesthesiologica Taiwanica, 2013-12, Vol.51 (4), p.171-176

2013

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Towards understanding sex differences in visceral pain: Enhanced reactivation of classically-conditioned fear in healthy women

Neurobiology of learning and memory, 2014-03, Vol.109, p.113-121

2014

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Chronic Visceral Pain: New Peripheral Mechanistic Insights and Resulting Treatments

Gut enterochromaffin cells drive visceral pain and anxiety

Regional neuroplastic brain changes in patients with chronic inflammatory and non-inflammatory visceral pain

IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain

Effect of electroacupuncture on P2X3 receptor regulation in the peripheral and central nervous systems of rats with visceral pain caused by irritable bowel syndrome

Common and distinct neural representations of aversive somatic and visceral stimulation in healthy individuals

NaV1.1 inhibition can reduce visceral hypersensitivity

Enhanced spinal neuronal responses as a mechanism for increased number and size of active acupoints in visceral hyperalgesia

Oral treatment with plecanatide or dolcanatide attenuates visceral hypersensitivity via activation of guanylate cyclase-C in rat models

Probiotics VSL#3 protect against development of visceral pain in murine model of irritable bowel syndrome

Gabapentin Effects on PKC-ERK1/2 Signaling in the Spinal Cord of Rats with Formalin-Induced Visceral Inflammatory Pain

Zeta Inhibitory Peptide as a Novel Therapy to Control Chronic Visceral Hypersensitivity in a Rat Model

Visceral and somatic pain modalities reveal Na V 1.7-independent visceral nociceptive pathways

The voltage-gated sodium channel NaV 1.9 in visceral pain

5-HT 3 receptor signaling in serotonin transporter-knockout rats: a female sex-specific animal model of visceral hypersensitivity

Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner

Colitis-Induced Microbial Perturbation Promotes Postinflammatory Visceral Hypersensitivity

Ameliorative effect of chlorpromazine hydrochloride on visceral hypersensitivity in rats: possible involvement of 5-HT 2A receptor

Parasympathetic activity correlates with subjective and brain responses to rectal distension in healthy subjects but not in non-constipated patients with irritable bowel syndrome

Differential Activation in Amygdala and Plasma Noradrenaline during Colorectal Distention by Administration of Corticotropin-Releasing Hormone between Healthy Individuals and Patients with Irritable Bowel Syndrome

How positive and negative expectations shape the experience of visceral pain

Colonic overexpression of the T-type calcium channel Ca v 3.2 in a mouse model of visceral hypersensitivity and in irritable bowel syndrome patients

Nalbuphine alleviates inflammation by down-regulating NF-κB in an acute inflammatory visceral pain rat model

MicroRNA-based therapy in pain medicine: Current progress and future prospects

Towards understanding sex differences in visceral pain: Enhanced reactivation of classically-conditioned fear in healthy women

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