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Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (28), p.11381-11386

2011

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RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex

The Journal of cell biology, 2013-09, Vol.202 (6), p.917-935

2013

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SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity

Science (American Association for the Advancement of Science), 2024-03, Vol.383 (6686), p.eadk1291

2024

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The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif

Scientific reports, 2019-06, Vol.9 (1), p.9126-15, Article 9126

2019

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Diversity of mechanisms in Ras-GAP catalysis of guanosine triphosphate hydrolysis revealed by molecular modeling

Organic & biomolecular chemistry, 2019-05, Vol.17 (19), p.4879-4891

2019

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Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

Nature communications, 2019-09, Vol.10 (1), p.3975-13, Article 3975

2019

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IQGAP1 promotes pancreatic cancer progression and epithelial-mesenchymal transition (EMT) through Wnt/β-catenin signaling

Scientific reports, 2019-05, Vol.9 (1), p.7539-12, Article 7539

2019

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Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (6), p.2485-2490

2010

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Inhibition of polar actin assembly by astral microtubules is required for cytokinesis

Nature communications, 2021-04, Vol.12 (1), p.2409-2409, Article 2409

2021

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Single-molecule imaging of a three-component ordered actin disassembly mechanism

Nature communications, 2015-05, Vol.6 (1), p.7202-7202, Article 7202

2015

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Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks

The Journal of biological chemistry, 2019-11, Vol.294 (44), p.16198-16213

2019

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Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling

Scientific reports, 2017-07, Vol.7 (1), p.5272-12, Article 5272

2017

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The Campylobacter jejuni CiaD effector co-opts the host cell protein IQGAP1 to promote cell entry

Nature communications, 2021-02, Vol.12 (1), p.1339-1339, Article 1339

2021

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Elucidating microscopic events driven by GTP hydrolysis reaction in the Ras-GAP system with semi-reactive molecular dynamics simulations: the alternative role of a phosphate binding loop for mechanical energy storage

Physical chemistry chemical physics : PCCP, 2021-12, Vol.23 (46), p.26151-26164

2021

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Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras

Scientific reports, 2019-07, Vol.9 (1), p.11057-13, Article 11057

2019

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Real-Time Monitoring of RAS Activity Using In Vitro and In-Cell NMR Spectroscopy

Methods in molecular biology (Clifton, N.J.), 2024, Vol.2797, p.237

2024

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Mutant p53 potentiates the oncogenic effects of insulin by inhibiting the tumor suppressor DAB2IP

Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (29), p.7623-7628

2017

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IQGAP1 and NWASP promote human cancer cell dissemination and metastasis by regulating β1-integrin via FAK and MRTF/SRF

Cell reports (Cambridge), 2024-04, Vol.43 (4), p.113989-113989, Article 113989

2024

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Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity

Scientific reports, 2020-04, Vol.10 (1), p.5753-5753, Article 5753

2020

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SynGAP isoforms exert opposing effects on synaptic strength

Nature communications, 2012-06, Vol.3 (1), p.900-900, Article 900

2012

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DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (47), p.19878-19883

2009

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Syngap1 regulates experience-dependent cortical ensemble plasticity by promoting in vivo excitatory synapse strengthening

Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (34), p.1

2021

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SynGAP regulates protein synthesis and homeostatic synaptic plasticity in developing cortical networks

PloS one, 2013-12, Vol.8 (12), p.e83941-e83941

2013

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Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (30), p.12353-12358

2007

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Neurofibromin 1 in mushroom body neurons mediates circadian wake drive through activating cAMP-PKA signaling

Nature communications, 2021-10, Vol.12 (1), p.5758-5758, Article 5758

2021

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Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex

RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex

SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity

The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif

Diversity of mechanisms in Ras-GAP catalysis of guanosine triphosphate hydrolysis revealed by molecular modeling

Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

IQGAP1 promotes pancreatic cancer progression and epithelial-mesenchymal transition (EMT) through Wnt/β-catenin signaling

Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis

Inhibition of polar actin assembly by astral microtubules is required for cytokinesis

Single-molecule imaging of a three-component ordered actin disassembly mechanism

Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling

The Campylobacter jejuni CiaD effector co-opts the host cell protein IQGAP1 to promote cell entry

Elucidating microscopic events driven by GTP hydrolysis reaction in the Ras-GAP system with semi-reactive molecular dynamics simulations: the alternative role of a phosphate binding loop for mechanical energy storage

Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras

Real-Time Monitoring of RAS Activity Using In Vitro and In-Cell NMR Spectroscopy

Mutant p53 potentiates the oncogenic effects of insulin by inhibiting the tumor suppressor DAB2IP

IQGAP1 and NWASP promote human cancer cell dissemination and metastasis by regulating β1-integrin via FAK and MRTF/SRF

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity

SynGAP isoforms exert opposing effects on synaptic strength

DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis

Syngap1 regulates experience-dependent cortical ensemble plasticity by promoting in vivo excitatory synapse strengthening

SynGAP regulates protein synthesis and homeostatic synaptic plasticity in developing cortical networks

Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers

Neurofibromin 1 in mushroom body neurons mediates circadian wake drive through activating cAMP-PKA signaling

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