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Structural identification of a hotspot on CFTR for potentiation

Science (American Association for the Advancement of Science), 2019-06, Vol.364 (6446), p.1184-1188

2019

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A novel strategy for the functionalization and design of 4-methylene-4 H -pyran merocyanines via enamination and 1,8-conjugate addition

Organic & biomolecular chemistry, 2023-01, Vol.21 (3), p.600-620

2023

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Real-Time Tracking and In Vivo Visualization of β‑Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe

Journal of the American Chemical Society, 2016-04, Vol.138 (16), p.5334-5340

2016

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2-(2-(Dimethylamino)vinyl)-4 H -pyran-4-ones as Novel and Convenient Building-Blocks for the Synthesis of Conjugated 4-Pyrone Derivatives

Molecules (Basel, Switzerland), 2022-12, Vol.27 (24)

2022

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Salinomycin kills cancer stem cells by sequestering iron in lysosomes

Nature chemistry, 2017-10, Vol.9 (10), p.1025-1033

2017

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Pd-Catalyzed Ligand-Directed Divergent Cycloaddition of Cyclic 1‑Azadienes with Oxo-1,4-dipoles

Organic letters, 2023-07, Vol.25 (27), p.5011-5016

2023

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Strategies for the construction of tetrahydropyran rings in the synthesis of natural products

Organic & biomolecular chemistry, 2014-06, Vol.12 (21), p.3323-3335

2014

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Enantioselective Synthesis of Dihydrospiro[indoline-3,4′-pyrano[2,3‑c]pyrazole] Derivatives via Michael/Hemiketalization Reaction

Organic letters, 2016-03, Vol.18 (6), p.1354-1357

2016

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Synthesis of Rare 6‑Deoxy‑d‑/l‑Heptopyranosyl Fluorides: Assembly of a Hexasaccharide Corresponding to Campylobacter jejuni Strain CG8486 Capsular Polysaccharide

Journal of the American Chemical Society, 2021-07, Vol.143 (29), p.11171-11179

2021

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Hydroxyl-Directed Ruthenium-Catalyzed C–H Bond Functionalization: Versatile Access to Fluorescent Pyrans

Organic letters, 2012-07, Vol.14 (13), p.3416-3419

2012

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Enantioselective Synthesis of Thailanstatin A Methyl Ester and Evaluation of in Vitro Splicing Inhibition

Journal of organic chemistry, 2018-05, Vol.83 (9), p.5187-5198

2018

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Total Syntheses of Thailanstatins A–C, Spliceostatin D, and Analogues Thereof. Stereodivergent Synthesis of Tetrasubstituted Dihydro- and Tetrahydropyrans and Design, Synthesis, Biological Evaluation, and Discovery of Potent Antitumor Agents

Journal of the American Chemical Society, 2018-07, Vol.140 (26), p.8303-8320

2018

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SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis

Nature (London), 2017-09, Vol.549 (7673), p.502-506

2017

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Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (13), p.3509-3514

2016

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Multi-Stimuli Sensitive Amphiphilic Block Copolymer Assemblies

Journal of the American Chemical Society, 2009-04, Vol.131 (13), p.4830-4838

2009

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Terminal Olefins to Chromans, Isochromans, and Pyrans via Allylic C–H Oxidation

Journal of the American Chemical Society, 2014-08, Vol.136 (31), p.10834-10837

2014

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Multifunctional organoboron compounds for scalable natural product synthesis

Nature (London), 2014-09, Vol.513 (7518), p.367-374

2014

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An Enantioselective Cross-Dehydrogenative Coupling Catalysis Approach to Substituted Tetrahydropyrans

Journal of the American Chemical Society, 2018-05, Vol.140 (20), p.6212-6216

2018

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Efficient Construction of Pyrano[3,2-a]carbazoles: Application to a Biomimetic Total Synthesis of Cyclized Monoterpenoid Pyrano[3,2-a]carbazole Alkaloids

Chemistry : a European journal, 2013-10, Vol.19 (42), p.14098-14111

2013

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Copper Catalyzed β‑Difluoroacetylation of Dihydropyrans and Glycals by Means of Direct C–H Functionalization

Organic letters, 2013-07, Vol.15 (13), p.3428-3431

2013

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Asymmetric synthesis of a structurally and stereochemically complex spirooxindole pyran scaffold through an organocatalytic multicomponent cascade reaction

Chemical communications (Cambridge, England), 2012-11, Vol.48 (85), p.10487-10489

2012

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Total Synthesis and Structural Revision of the Cytotoxin Aruncin B

Organic letters, 2016-09, Vol.18 (17), p.4364-4367

2016

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Targeted Genome Mining Reveals the Biosynthetic Gene Clusters of Natural Product CYP51 Inhibitors

Journal of the American Chemical Society, 2021-04, Vol.143 (16), p.6043-6047

2021

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An asymmetric assembly of spirooxindole dihydropyranones through a direct enantioselective organocatalytic vinylogous aldol-cyclization cascade reaction of 3-alkylidene oxindoles with isatins

Chemical communications (Cambridge, England), 2016-02, Vol.52 (11), p.2322-2325

2016

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Recent applications in natural product synthesis of dihydrofuran and -pyran formation by ring-closing alkene metathesis

Organic & biomolecular chemistry, 2016-01, Vol.14 (25), p.5875-5893

2016

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Structural identification of a hotspot on CFTR for potentiation

A novel strategy for the functionalization and design of 4-methylene-4 H -pyran merocyanines via enamination and 1,8-conjugate addition

Real-Time Tracking and In Vivo Visualization of β‑Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe

2-(2-(Dimethylamino)vinyl)-4 H -pyran-4-ones as Novel and Convenient Building-Blocks for the Synthesis of Conjugated 4-Pyrone Derivatives

Salinomycin kills cancer stem cells by sequestering iron in lysosomes

Pd-Catalyzed Ligand-Directed Divergent Cycloaddition of Cyclic 1‑Azadienes with Oxo-1,4-dipoles

Strategies for the construction of tetrahydropyran rings in the synthesis of natural products

Enantioselective Synthesis of Dihydrospiro[indoline-3,4′-pyrano[2,3‑c]pyrazole] Derivatives via Michael/Hemiketalization Reaction

Synthesis of Rare 6‑Deoxy‑d‑/l‑Heptopyranosyl Fluorides: Assembly of a Hexasaccharide Corresponding to Campylobacter jejuni Strain CG8486 Capsular Polysaccharide

Hydroxyl-Directed Ruthenium-Catalyzed C–H Bond Functionalization: Versatile Access to Fluorescent Pyrans

Enantioselective Synthesis of Thailanstatin A Methyl Ester and Evaluation of in Vitro Splicing Inhibition

Total Syntheses of Thailanstatins A–C, Spliceostatin D, and Analogues Thereof. Stereodivergent Synthesis of Tetrasubstituted Dihydro- and Tetrahydropyrans and Design, Synthesis, Biological Evaluation, and Discovery of Potent Antitumor Agents

SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis

Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives

Multi-Stimuli Sensitive Amphiphilic Block Copolymer Assemblies

Terminal Olefins to Chromans, Isochromans, and Pyrans via Allylic C–H Oxidation

Multifunctional organoboron compounds for scalable natural product synthesis

An Enantioselective Cross-Dehydrogenative Coupling Catalysis Approach to Substituted Tetrahydropyrans

Efficient Construction of Pyrano[3,2-a]carbazoles: Application to a Biomimetic Total Synthesis of Cyclized Monoterpenoid Pyrano[3,2-a]carbazole Alkaloids

Copper Catalyzed β‑Difluoroacetylation of Dihydropyrans and Glycals by Means of Direct C–H Functionalization

Asymmetric synthesis of a structurally and stereochemically complex spirooxindole pyran scaffold through an organocatalytic multicomponent cascade reaction

Total Synthesis and Structural Revision of the Cytotoxin Aruncin B

Targeted Genome Mining Reveals the Biosynthetic Gene Clusters of Natural Product CYP51 Inhibitors

An asymmetric assembly of spirooxindole dihydropyranones through a direct enantioselective organocatalytic vinylogous aldol-cyclization cascade reaction of 3-alkylidene oxindoles with isatins

Recent applications in natural product synthesis of dihydrofuran and -pyran formation by ring-closing alkene metathesis

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