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661W is a retinal ganglion precursor-like cell line in which glaucoma-associated optineurin mutants induce cell death selectively

Scientific reports, 2017-12, Vol.7 (1), p.16855-13, Article 16855

2017

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A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin

PloS one, 2015-09, Vol.10 (9), p.e0138289-e0138289

2015

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Optineurin is required for CYLD-dependent inhibition of TNFα-induced NF-κB activation

PloS one, 2011-03, Vol.6 (3), p.e17477

2011

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E50K-OPTN-induced retinal cell death involves the Rab GTPase-activating protein, TBC1D17 mediated block in autophagy

PloS one, 2014-04, Vol.9 (4), p.e95758-e95758

2014

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Autophagy receptor optineurin promotes autophagosome formation by potentiating LC3-II production and phagophore maturation

Communicative & integrative biology, 2018-03, Vol.11 (2), p.1-4

2018

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Umakant Waman Kenkare (1927–2019)

Current science (Bangalore), 2020-09, Vol.119 (6), p.1055-1055

Swarup, Ghanshyam

2020

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Optineurin mediates negative regulation of Rab8 function by TBC1D17, a GTPase activating protein

Journal of cell science, 2012-01

2012

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HSC70 regulates cold-induced caspase-1 hyperactivation by an autoinflammation-causing mutant of cytoplasmic immune receptor NLRC4

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (43), p.21694-21703

2019

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NF-κB Mediates Tumor Necrosis Factor α-Induced Expression of Optineurin, a Negative Regulator of NF-κB

PloS one, 2009-04, Vol.4 (4), p.e5114

2009

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Interaction with Sug1 enables Ipaf ubiquitination leading to caspase 8 activation and cell death

Biochemical journal, 2010-04, Vol.427 (1), p.91-104

2010

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Functional analysis of optineurin and some of its disease-associated mutants: Functional Analysis of Optineurin and its Disease-Associated Mutants

IUBMB life, 2015-02, Vol.67 (2), p.120-128

2015

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Tumor necrosis factor-alpha-induced caspase-1 gene expression. Role of p73

The FEBS journal, 2007-09, Vol.274 (17), p.4396-4407

2007

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NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB

PloS one, 2009, Vol.4 (4), p.e5114-e5114

2009

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Optineurin Is Required for CYLD-Dependent Inhibition of TNF[alpha]-Induced NF-[kappa]B Activation

PloS one, 2011-03, Vol.6 (3), p.e17477

2011

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Regulation of cellular and molecular functions by protein phosphorylation

Resonance, 1998-10, Vol.3 (10), p.70-78

Swarup, Ghanshyam

1998

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C3G is required for c-Abl-induced filopodia and its overexpression promotes filopodia formation

Experimental cell research, 2007-07, Vol.313 (11), p.2476-2492

2007

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NF-[kappa]B Mediates Tumor Necrosis Factor [alpha]-Induced Expression of Optineurin, a Negative Regulator of NF-[kappa]B

PloS one, 2009-04, Vol.4 (4), p.e5114

2009

Volltextzugriff (PDF)

Tumor necrosis factor-[alpha]-induced caspase-1 gene expression

The FEBS journal, 2007-09, Vol.274 (17), p.4396

2007

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Role of p73 in Regulating Human Caspase-1 Gene Transcription Induced by Interferon-Î³ and Cisplatin

The Journal of biological chemistry, 2005-11, Vol.280 (44), p.36664

2005

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Role of p73 in regulating human caspase-1 gene transcription induced by interferon-{gamma} and cisplatin

The Journal of biological chemistry, 2005-11, Vol.280 (44), p.36664

2005

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Erratum to “C3G is required for c-Abl-induced filopodia and its overexpression promotes filopodia formation” [Exp. Cell Res. 313 (2007) 2476–2492]

Experimental cell research, 2007-09, Vol.313 (15), p.3376-3376

2007

Volltextzugriff (PDF)

A cataract-causing connexin 50 mutant is mislocalized to the ER due to loss of the fourth transmembrane domain and cytoplasmic domain

FEBS open bio, 2013-01, Vol.3 (1), p.22-29

2013

Volltextzugriff (PDF)

Functional Defects Caused by Glaucoma – Associated Mutations in Optineurin

Swarup, Ghanshyam

2013

Volltextzugriff (PDF)

Nuclear protein tyrosine phosphatases and control of cell proliferation

Current science (Bangalore), 1997-09, Vol.73 (5), p.418-429

1997

Volltextzugriff (PDF)

Regulatory role of protein phosphorylation recognized

Current science (Bangalore), 1992-12, Vol.63 (11), p.653-654

Swarup, Ghanshyam

1992

Volltextzugriff (PDF)

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661W is a retinal ganglion precursor-like cell line in which glaucoma-associated optineurin mutants induce cell death selectively

A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin

Optineurin is required for CYLD-dependent inhibition of TNFα-induced NF-κB activation

E50K-OPTN-induced retinal cell death involves the Rab GTPase-activating protein, TBC1D17 mediated block in autophagy

Autophagy receptor optineurin promotes autophagosome formation by potentiating LC3-II production and phagophore maturation

Umakant Waman Kenkare (1927–2019)

Optineurin mediates negative regulation of Rab8 function by TBC1D17, a GTPase activating protein

HSC70 regulates cold-induced caspase-1 hyperactivation by an autoinflammation-causing mutant of cytoplasmic immune receptor NLRC4

NF-κB Mediates Tumor Necrosis Factor α-Induced Expression of Optineurin, a Negative Regulator of NF-κB

Interaction with Sug1 enables Ipaf ubiquitination leading to caspase 8 activation and cell death

Functional analysis of optineurin and some of its disease-associated mutants: Functional Analysis of Optineurin and its Disease-Associated Mutants

Tumor necrosis factor-alpha-induced caspase-1 gene expression. Role of p73

NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB

Optineurin Is Required for CYLD-Dependent Inhibition of TNF[alpha]-Induced NF-[kappa]B Activation

Regulation of cellular and molecular functions by protein phosphorylation

C3G is required for c-Abl-induced filopodia and its overexpression promotes filopodia formation

NF-[kappa]B Mediates Tumor Necrosis Factor [alpha]-Induced Expression of Optineurin, a Negative Regulator of NF-[kappa]B

Tumor necrosis factor-[alpha]-induced caspase-1 gene expression

Role of p73 in Regulating Human Caspase-1 Gene Transcription Induced by Interferon-Î³ and Cisplatin

Role of p73 in regulating human caspase-1 gene transcription induced by interferon-{gamma} and cisplatin

Erratum to “C3G is required for c-Abl-induced filopodia and its overexpression promotes filopodia formation” [Exp. Cell Res. 313 (2007) 2476–2492]

A cataract-causing connexin 50 mutant is mislocalized to the ER due to loss of the fourth transmembrane domain and cytoplasmic domain

Functional Defects Caused by Glaucoma – Associated Mutations in Optineurin

Nuclear protein tyrosine phosphatases and control of cell proliferation

Regulatory role of protein phosphorylation recognized

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