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Alpha2-adrenoreceptors profile modulation. 4. From antagonist to agonist behavior

Journal of medicinal chemistry, 2008-07, Vol.51 (14), p.4289-4299

2008

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alpha2A-adrenoceptor antagonism increases insulin secretion and synergistically augments the insulinotropic effect of glibenclamide in mice

British journal of pharmacology, 2008-07, Vol.154 (6), p.1287

2008

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The second extracellular loop of alpha2A-adrenoceptors contributes to the binding of yohimbine analogues

British journal of pharmacology, 2007-08, Vol.151 (8), p.1293-1304

2007

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Spatial working memory improvement by an alpha2-adrenoceptor agonist dexmedetomidine is not mediated through alpha2C-adrenoceptor

Progress in neuro-psychopharmacology & biological psychiatry, 2001-11, Vol.25 (8), p.1539-1554

2001

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Evaluation of the alpha2C-adrenoceptor as a neuropsychiatric drug target studies in transgenic mouse models

Life sciences (1973), 2001-04, Vol.68 (19-20), p.2277-2285

2001

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Ligand recognition of serine-cysteine amino acid exchanges in transmembrane domain 5 of alpha2-adrenergic receptors by UK 14,304

Journal of neurochemistry, 2000-04, Vol.74 (4), p.1705-1710

2000

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Genetic alteration of the alpha2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels

Molecular psychiatry, 1999-09, Vol.4 (5), p.443-452

1999

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Role of alpha2C-adrenoceptor subtype in spatial working memory as revealed by mice with targeted disruption of the alpha2C-adrenoceptor gene

The European journal of neuroscience, 1999-02, Vol.11 (2), p.599-603

1999

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Modulation of agonist binding to recombinant human alpha2-adrenoceptors by sodium ions

Biochimica et biophysica acta, 1998-11, Vol.1448 (1), p.135

1998

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D-amphetamine and L-5-hydroxytryptophan-induced behaviours in mice with genetically-altered expression of the alpha2C-adrenergic receptor subtype

Neuroscience, 1998-10, Vol.86 (3), p.959-965

1998

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Alpha2C-adrenoceptor-overexpressing mice are impaired in executing nonspatial and spatial escape strategies

Molecular pharmacology, 1998-09, Vol.54 (3), p.569-576

1998

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Adrenergic alpha2C-receptors modulate the acoustic startle reflex, prepulse inhibition, and aggression in mice

The Journal of neuroscience, 1998-04, Vol.18 (8), p.3035

1998

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Gene targeting — homing in on α 2-adrenoceptor-subtype function

Trends in pharmacological sciences (Regular ed.), 1997-06, Vol.18 (6), p.211-219

1997

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Genetic alteration of alpha 2C-adrenoceptor expression in mice: influence on locomotor, hypothermic, and neurochemical effects of dexmedetomidine, a subtype-nonselective alpha 2-adrenoceptor agonist

Molecular pharmacology, 1997-01, Vol.51 (1), p.36-46

1997

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Targeted inactivation of the gene encoding the mouse alpha 2c-adrenoceptor homolog

Molecular pharmacology, 1995-07, Vol.48 (1), p.48-55

1995

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Recombinant human alpha 2-adrenoceptor subtypes: comparison of [3H]rauwolscine, [3H]atipamezole and [3H]RX821002 as radioligands

Biochimica et biophysica acta, 1995-04, Vol.1266 (2), p.207

1995

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Coupling of human alpha 2-adrenoceptor subtypes to regulation of cAMP production in transfected S115 cells

European journal of pharmacology, 1994-01, Vol.266 (2), p.165-174

1994

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Use of recombinant human alpha 2-adrenoceptors to characterize subtype selectively of antagonist binding

European journal of pharmacology, 1993-08, Vol.246 (3), p.219-226

1993

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Comparison of the behavioral and neurochemical effects of the two optical enantiomers of medetomidine, a selective alpha-2-adrenoceptor agonist

The Journal of pharmacology and experimental therapeutics, 1991-11, Vol.259 (2), p.848

1991

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Alpha2-adrenoreceptors profile modulation. 4. From antagonist to agonist behavior

alpha2A-adrenoceptor antagonism increases insulin secretion and synergistically augments the insulinotropic effect of glibenclamide in mice

The second extracellular loop of alpha2A-adrenoceptors contributes to the binding of yohimbine analogues

Spatial working memory improvement by an alpha2-adrenoceptor agonist dexmedetomidine is not mediated through alpha2C-adrenoceptor

Evaluation of the alpha2C-adrenoceptor as a neuropsychiatric drug target studies in transgenic mouse models

Ligand recognition of serine-cysteine amino acid exchanges in transmembrane domain 5 of alpha2-adrenergic receptors by UK 14,304

Genetic alteration of the alpha2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels

Role of alpha2C-adrenoceptor subtype in spatial working memory as revealed by mice with targeted disruption of the alpha2C-adrenoceptor gene

Modulation of agonist binding to recombinant human alpha2-adrenoceptors by sodium ions

D-amphetamine and L-5-hydroxytryptophan-induced behaviours in mice with genetically-altered expression of the alpha2C-adrenergic receptor subtype

Alpha2C-adrenoceptor-overexpressing mice are impaired in executing nonspatial and spatial escape strategies

Adrenergic alpha2C-receptors modulate the acoustic startle reflex, prepulse inhibition, and aggression in mice

Gene targeting — homing in on α 2-adrenoceptor-subtype function

Genetic alteration of alpha 2C-adrenoceptor expression in mice: influence on locomotor, hypothermic, and neurochemical effects of dexmedetomidine, a subtype-nonselective alpha 2-adrenoceptor agonist

Targeted inactivation of the gene encoding the mouse alpha 2c-adrenoceptor homolog

Recombinant human alpha 2-adrenoceptor subtypes: comparison of [3H]rauwolscine, [3H]atipamezole and [3H]RX821002 as radioligands

Coupling of human alpha 2-adrenoceptor subtypes to regulation of cAMP production in transfected S115 cells

Use of recombinant human alpha 2-adrenoceptors to characterize subtype selectively of antagonist binding

Comparison of the behavioral and neurochemical effects of the two optical enantiomers of medetomidine, a selective alpha-2-adrenoceptor agonist

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