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Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies

PloS one, 2013-08, Vol.8 (8), p.e71196

2013

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Fluorinated nucleosides: Synthesis and biological implication

Journal of fluorine chemistry, 2008-09, Vol.129 (9), p.743-766

2008

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Synthesis of an Anti-hepatitis B Agent, 2′-Fluoro-6′-methylene-carbocyclic Adenosine (FMCA) and Its Phosphoramidate (FMCAP)

Journal of organic chemistry, 2019-01, Vol.84 (2), p.752-759

2019

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Stereoselective Synthesis of 2′-Fluoro-6′-methylene Carbocyclic Adenosine via Vince Lactam

Journal of organic chemistry, 2014-05, Vol.79 (9), p.3917-3923

2014

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A Stereoselective Synthesis of 4′‐α‐Fluoro‐methyl Carbocyclic Nucleoside Analogs

ChemistrySelect (Weinheim), 2023-07, Vol.8 (26), p.n/a

2023

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Antiviral Nucleosides: Chiral Synthesis and Chemotherapy

Chu, C. K

1, 2003

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Synthesis of Novel Spiro[2.3]hexane Carbocyclic Nucleosides via Enzymatic Resolution

Organic letters, 2004-07, Vol.6 (15), p.2531-2534

2004

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Synthesis and Potent Anti-HIV Activity of l-3‘-Fluoro-2‘,3‘-Unsaturated Cytidine

Organic letters, 2001-12, Vol.3 (26), p.4177-4180

2001

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Enantioselective Synthesis of β‑l‑5-[(E)‑2-Bromovinyl)-1-((2S,4S)‑2-(hydroxymethyl)-1,3-(dioxolane-4-yl) Uracil)] (l‑BHDU) via Chiral Pure l‑Dioxolane

Journal of organic chemistry, 2024-07, Vol.89 (13), p.9313-9321

2024

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Enantioselective Synthesis of β-l-5-(E)-2-Bromovinyl)-1-((2S,4S)-2-(hydroxymethyl)-1,3-(dioxolane-4-yl) Uracil) (l-BHDU) via Chiral Pure l-Dioxolane

Journal of organic chemistry, 2024-07, Vol.89 (13), p.9313

2024

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Metabolism of the Anti-Hepatitis C Virus Nucleoside β-d-N4-Hydroxycytidine in Different Liver Cells

Antimicrobial Agents and Chemotherapy, 2004-12, Vol.48 (12), p.4636-4642

2004

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Synthesis, biological evaluation and molecular modeling studies of N-benzyladenosine analogues as potential anti-toxoplasma agents

Biochemical pharmacology, 2007-05, Vol.73 (10), p.1558-1572

2007

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Asymmetric synthesis and biological evaluation of .beta.-L-(2R,5S)- and .alpha.-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential anti-HIV agents

Journal of medicinal chemistry, 1993-01, Vol.36 (2), p.181-195

1993

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Practical Synthesis of d- and l-2-Cyclopentenone and Their Utility for the Synthesis of Carbocyclic Antiviral Nucleosides against Orthopox Viruses (Smallpox, Monkeypox, and Cowpox Virus)

Journal of organic chemistry, 2003-11, Vol.68 (23), p.9012-9018

2003

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Synthesis of enantiomerically pure (2'R,5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl)cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV)

Journal of organic chemistry, 1992-04, Vol.57 (8), p.2217-2219

1992

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L-nucleosides: antiviral activity and molecular mechanism

Current topics in medicinal chemistry, 2002-10, Vol.2 (10), p.1065

2002

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L-.beta.-(2S,4S)- and L-.alpha.-(2S,4R)-dioxolanyl nucleosides as potential anti-HIV agents: asymmetric synthesis and structure-activity relationships

Journal of medicinal chemistry, 1993-03, Vol.36 (5), p.519-528

1993

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Antiviral Activity of Nucleoside Analogues against SARS-coronavirus (SARS-CoV)

Antiviral chemistry & chemotherapy, 2006-10, Vol.17 (5), p.285-289

2006

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Synthesis of Entecavir and Its Novel Class of Analogs

Current Protocols in Nucleic Acid Chemistry, 2011-12, Vol.47 (1), p.14.7.1-14.7.17

2011

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A highly stereoselective synthesis of anti-HIV 2',3'-dideoxy- and 2',3'-didehydro-2',3'-dideoxynucleosides

Journal of organic chemistry, 1992-07, Vol.57 (14), p.3887-3894

1992

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Synthesis of l-Oxetanocin

Organic letters, 2002-04, Vol.4 (7), p.1147-1149

2002

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Efficient and practical synthesis of d-cyclopent-2-enone, the key intermediate for the synthesis of carbocyclic nucleosides

Tetrahedron letters, 2002-06, Vol.43 (23), p.4141-4143

2002

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Synthesis and anti-HIV activity of l-β-3′- C-cyano-2′,3′-unsaturated nucleosides and l-3′- C-cyano-3′-deoxyribonucleosides

Tetrahedron, 2003-08, Vol.59 (34), p.6423-6431

2003

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Synthesis of 3‘-Fluoro-2‘,3‘-dideoxy-2‘,3‘-didehydro-4‘-ethynyl-d- and -l-furanosyl Nucleosides

Journal of organic chemistry, 2004-09, Vol.69 (18), p.6034-6041

2004

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Stereocontrolled Syntheses of Carbocyclic C-Nucleosides and Related Compounds

Journal of organic chemistry, 2001-07, Vol.66 (14), p.4852-4858

2001

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1 – 25 von 830

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Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies

Fluorinated nucleosides: Synthesis and biological implication

Synthesis of an Anti-hepatitis B Agent, 2′-Fluoro-6′-methylene-carbocyclic Adenosine (FMCA) and Its Phosphoramidate (FMCAP)

Stereoselective Synthesis of 2′-Fluoro-6′-methylene Carbocyclic Adenosine via Vince Lactam

A Stereoselective Synthesis of 4′‐α‐Fluoro‐methyl Carbocyclic Nucleoside Analogs

Antiviral Nucleosides: Chiral Synthesis and Chemotherapy

Synthesis of Novel Spiro[2.3]hexane Carbocyclic Nucleosides via Enzymatic Resolution

Synthesis and Potent Anti-HIV Activity of l-3‘-Fluoro-2‘,3‘-Unsaturated Cytidine

Enantioselective Synthesis of β‑l‑5-[(E)‑2-Bromovinyl)-1-((2S,4S)‑2-(hydroxymethyl)-1,3-(dioxolane-4-yl) Uracil)] (l‑BHDU) via Chiral Pure l‑Dioxolane

Enantioselective Synthesis of β-l-5-(E)-2-Bromovinyl)-1-((2S,4S)-2-(hydroxymethyl)-1,3-(dioxolane-4-yl) Uracil) (l-BHDU) via Chiral Pure l-Dioxolane

Metabolism of the Anti-Hepatitis C Virus Nucleoside β-d-N4-Hydroxycytidine in Different Liver Cells

Synthesis, biological evaluation and molecular modeling studies of N-benzyladenosine analogues as potential anti-toxoplasma agents

Asymmetric synthesis and biological evaluation of .beta.-L-(2R,5S)- and .alpha.-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential anti-HIV agents

Practical Synthesis of d- and l-2-Cyclopentenone and Their Utility for the Synthesis of Carbocyclic Antiviral Nucleosides against Orthopox Viruses (Smallpox, Monkeypox, and Cowpox Virus)

Synthesis of enantiomerically pure (2'R,5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl)cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV)

L-nucleosides: antiviral activity and molecular mechanism

L-.beta.-(2S,4S)- and L-.alpha.-(2S,4R)-dioxolanyl nucleosides as potential anti-HIV agents: asymmetric synthesis and structure-activity relationships

Antiviral Activity of Nucleoside Analogues against SARS-coronavirus (SARS-CoV)

Synthesis of Entecavir and Its Novel Class of Analogs

A highly stereoselective synthesis of anti-HIV 2',3'-dideoxy- and 2',3'-didehydro-2',3'-dideoxynucleosides

Synthesis of l-Oxetanocin

Efficient and practical synthesis of d-cyclopent-2-enone, the key intermediate for the synthesis of carbocyclic nucleosides

Synthesis and anti-HIV activity of l-β-3′- C-cyano-2′,3′-unsaturated nucleosides and l-3′- C-cyano-3′-deoxyribonucleosides

Synthesis of 3‘-Fluoro-2‘,3‘-dideoxy-2‘,3‘-didehydro-4‘-ethynyl-d- and -l-furanosyl Nucleosides

Stereocontrolled Syntheses of Carbocyclic C-Nucleosides and Related Compounds

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