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The Complexity and Multiplicity of the Specific cAMP Phosphodiesterase Family: PDE4, Open New Adapted Therapeutic Approaches

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10616

Lugnier, Claire

2022

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Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents

Pharmacology & therapeutics (Oxford), 2006-03, Vol.109 (3), p.366-398

Lugnier, Claire

2006

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The Endocrine Function of the Heart: Physiology and Involvements of Natriuretic Peptides and Cyclic Nucleotide Phosphodiesterases in Heart Failure

Journal of clinical medicine, 2019-10, Vol.8 (10), p.1746

2019

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Effect of the Phosphodiesterase 5 Inhibitor Sildenafil on Ischemia-Reperfusion-Induced Muscle Mitochondrial Dysfunction and Oxidative Stress

Antioxidants, 2019-04, Vol.8 (4), p.93

2019

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PDE4 inhibition as a therapeutic strategy for improvement of pulmonary dysfunctions in Covid-19 and cigarette smoking

Biochemical pharmacology, 2021-03, Vol.185, p.114431-114431, Article 114431

2021

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Cyclic nucleotide phosphodiesterases: New targets in the metabolic syndrome?

Pharmacology & therapeutics (Oxford), 2020-04, Vol.208, p.107475-107475, Article 107475

2020

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Study of the mechanisms involved in the vasorelaxation induced by (−)‐epigallocatechin‐3‐gallate in rat aorta

British journal of pharmacology, 2006-02, Vol.147 (3), p.269-280

2006

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Implication of cyclic nucleotide phosphodiesterase inhibition in the vasorelaxant activity of the citrus-fruits flavonoid (±)-naringenin

Planta medica, 2005-02, Vol.71 (2), p.99-107

2005

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Cyclic nucleotide phosphodiesterase (PDE) implication in lupus erythematosus: Effect of a new PDE4 inhibitor

Immunome research, 2017-01, Vol.13 (S1), p.44

Lugnier, Claire

2017

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Comparative study of the vasorelaxant activity, superoxide-scavenging ability and cyclic nucleotide phosphodiesterase-inhibitory effects of hesperetin and hesperidin

Naunyn-Schmiedeberg's archives of pharmacology, 2004-12, Vol.370 (6), p.452-463

2004

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Involvement of cyclic nucleotide‐dependent protein kinases in cyclic AMP‐mediated vasorelaxation

British journal of pharmacology, 1997-09, Vol.122 (1), p.158-164

1997

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Expression and role of phosphodiesterase 6 in the chicken pineal gland

Journal of neurochemistry, 2001-07, Vol.78 (1), p.88-99

2001

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Generation of PDE4 knockout mice by gene targeting

Methods in molecular biology (Clifton, N.J.), 2005, Vol.307, p.191

2005

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Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model

European journal of medicinal chemistry, 2019-09, Vol.177, p.269-290

2019

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Purification of PDE6 isozymes from mammalian retina

Methods in molecular biology (Clifton, N.J.), 2005, Vol.307, p.125

2005

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Investigation of extracellular signal-regulated kinase 2 mitogen-activated protein kinase phosphorylation and regulation of activity of PDE4 cyclic adenosine monophosphate-specific phosphodiesterases

Methods in molecular biology (Clifton, N.J.), 2005, Vol.307, p.225

2005

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Coupling of I1 Imidazoline Receptors to the cAMP Pathway: Studies with a Highly Selective Ligand, Benazoline

Molecular pharmacology, 2000-06, Vol.57 (6), p.1142

2000

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Characterization of cyclic nucleotide phosphodiesterase isoforms associated to isolated cardiac nuclei

Biochimica et biophysica acta, 1999-11, Vol.1472 (3), p.431-446

1999

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Purification, reconstitution on lipid vesicles, and assays of PDE6 and its activator G protein, transducin

Methods in molecular biology (Clifton, N.J.), 2005, Vol.307, p.289

2005

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Cyclic guanosine 5'-monophosphate binding to regulatory GAF domains of photoreceptor phosphodiesterase

Methods in molecular biology (Clifton, N.J.), 2005, Vol.307, p.141

Cote, Rick H

2005

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Radiolabeled ligand binding to the catalytic or allosteric sites of PDE5 and PDE11

Methods in molecular biology (Clifton, N.J.), 2005, Vol.307, p.239

2005

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Determining the subunit structure of phosphodiesterases using gel filtration and sucrose density gradient centrifugation

Methods in molecular biology (Clifton, N.J.), 2005, Vol.307, p.167

Richter, Wito

2005

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Anti-inflammatory activities of a new series of selective phosphodiesterase 4 inhibitors derived from 9-benzyladenine

The Journal of pharmacology and experimental therapeutics, 2000-02, Vol.292 (2), p.647

2000

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Endothelium‐dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors

British journal of pharmacology, 1991-10, Vol.104 (2), p.495-503

1991

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Statins Therapy Improves Acute Ischemic Stroke in Patients with Cardio-metabolic Disorders Measured by Lipoprotein-Associated Phospholipase A2 (Lp-PLA2): New Focal Point

Neurology India, 2021-11, Vol.69 (6), p.1637-1644

2021

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The Complexity and Multiplicity of the Specific cAMP Phosphodiesterase Family: PDE4, Open New Adapted Therapeutic Approaches

Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents

The Endocrine Function of the Heart: Physiology and Involvements of Natriuretic Peptides and Cyclic Nucleotide Phosphodiesterases in Heart Failure

Effect of the Phosphodiesterase 5 Inhibitor Sildenafil on Ischemia-Reperfusion-Induced Muscle Mitochondrial Dysfunction and Oxidative Stress

PDE4 inhibition as a therapeutic strategy for improvement of pulmonary dysfunctions in Covid-19 and cigarette smoking

Cyclic nucleotide phosphodiesterases: New targets in the metabolic syndrome?

Study of the mechanisms involved in the vasorelaxation induced by (−)‐epigallocatechin‐3‐gallate in rat aorta

Implication of cyclic nucleotide phosphodiesterase inhibition in the vasorelaxant activity of the citrus-fruits flavonoid (±)-naringenin

Cyclic nucleotide phosphodiesterase (PDE) implication in lupus erythematosus: Effect of a new PDE4 inhibitor

Comparative study of the vasorelaxant activity, superoxide-scavenging ability and cyclic nucleotide phosphodiesterase-inhibitory effects of hesperetin and hesperidin

Involvement of cyclic nucleotide‐dependent protein kinases in cyclic AMP‐mediated vasorelaxation

Expression and role of phosphodiesterase 6 in the chicken pineal gland

Generation of PDE4 knockout mice by gene targeting

Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model

Purification of PDE6 isozymes from mammalian retina

Investigation of extracellular signal-regulated kinase 2 mitogen-activated protein kinase phosphorylation and regulation of activity of PDE4 cyclic adenosine monophosphate-specific phosphodiesterases

Coupling of I1 Imidazoline Receptors to the cAMP Pathway: Studies with a Highly Selective Ligand, Benazoline

Characterization of cyclic nucleotide phosphodiesterase isoforms associated to isolated cardiac nuclei

Purification, reconstitution on lipid vesicles, and assays of PDE6 and its activator G protein, transducin

Cyclic guanosine 5'-monophosphate binding to regulatory GAF domains of photoreceptor phosphodiesterase

Radiolabeled ligand binding to the catalytic or allosteric sites of PDE5 and PDE11

Determining the subunit structure of phosphodiesterases using gel filtration and sucrose density gradient centrifugation

Anti-inflammatory activities of a new series of selective phosphodiesterase 4 inhibitors derived from 9-benzyladenine

Endothelium‐dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors

Statins Therapy Improves Acute Ischemic Stroke in Patients with Cardio-metabolic Disorders Measured by Lipoprotein-Associated Phospholipase A2 (Lp-PLA2): New Focal Point

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