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Cholesterol and Cancer, in the Balance

Science (American Association for the Advancement of Science), 2014-03, Vol.343 (6178), p.1445-1446

2014

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The prototypical inhibitor of cholesterol esterification, Sah 58-035 [3-[decyldimethylsilyl]-n-[2-(4-methylphenyl)-1-phenylethyl]propanamide], is an agonist of estrogen receptors

The Journal of pharmacology and experimental therapeutics, 2006-10, Vol.319 (1), p.139

2006

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Role of the Extracellular Domains of the Cholecystokinin Receptor in Agonist Binding

Molecular pharmacology, 1998-08, Vol.54 (2), p.364-371

1998

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Arginine 197 of the cholecystokinin-A receptor binding site interacts with the sulfate of the peptide agonist cholecystokinin

Protein science, 1999-11, Vol.8 (11), p.2347-2354

1999

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Met-195 of the Cholecystokinin-A Receptor Interacts with the Sulfated Tyrosine of Cholecystokinin and Is Crucial for Receptor Transition to High Affinity State

The Journal of biological chemistry, 1998-06, Vol.273 (23), p.14380-14386

1998

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A Segment of Five Amino Acids in the Second Extracellular Loop of the Cholecystokinin-B Receptor Is Essential for Selectivity of the Peptide Agonist Gastrin

The Journal of biological chemistry, 1996-06, Vol.271 (25), p.14698-14706

1996

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Evidence for a Direct Interaction between the Penultimate Aspartic Acid of Cholecystokinin and Histidine 207, Located in the Second Extracellular Loop of the Cholecystokinin B Receptor

The Journal of biological chemistry, 1999-08, Vol.274 (33), p.23191-23197

1999

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Dendrogenin A and B two new steroidal alkaloids increasing neural responsiveness in the deafened guinea pig

Frontiers in aging neuroscience, 2015-07, Vol.7, p.145-145

2015

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The Third Intracellular Loop of the Rat and Mouse Cholecystokinin-A Receptors Is Responsible for Different Patterns of Gene Activation

Molecular pharmacology, 2000-12, Vol.58 (6), p.1381-1388

2000

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The Biologically Crucial C Terminus of Cholecystokinin and the Non-peptide Agonist SR-146,131 Share a Common Binding Site in the Human CCK1 Receptor

The Journal of biological chemistry, 2002-03, Vol.277 (9), p.7546-7555

2002

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Abstract P3-05-12: Circulating oxysterol metabolites as potential new surrogate markers for hormonotherapy in patients with hormone receptor-positive breast cancer? A pilot study

Cancer research (Chicago, Ill.), 2015-05, Vol.75 (9_Supplement), p.P3-P3-05-12

2015

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Abstract 1165: Identification of a cholesterol onco-metabolite, promoter of tumor in breast cancers, and of the enzyme involved in its biosynthesis

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.1165-1165

2015

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Mutation of Asn-391 within the Conserved NPXXY Motif of the Cholecystokinin B Receptor Abolishes Gq Protein Activation without Affecting Its Association with the Receptor

The Journal of biological chemistry, 2000-06, Vol.275 (23), p.17321-17327

2000

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Abstract 5238: Characterization of the enzyme generating the cholesterol metabolite and tumor suppressor dendrogenin A in the breast and its deregulations in breast cancer

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5238-5238

2018

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Abstract 1884: 6-oxo-cholestan-3β,5α-diol (OCDO) is a metabolite produced in tumors by cholesterol epoxide hydrolase activity and a tumor promoter: OCDO inhibition contributes to the anti-tumor activity of tamoxifen and dendrogenin A

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.1884-1884

2013

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The biologically crucial C terminus of cholecystokinin and the non-peptide agonist SR-146,131 share a common binding site in the human CCK1 receptor. Evidence for a crucial role of Met-121 in the activation process

The Journal of biological chemistry, 2002-03, Vol.277 (9), p.7546

2002

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Ligand-induced Internalization of Cholecystokinin Receptors

The Journal of biological chemistry, 1997-07, Vol.272 (29), p.18179-18184

1997

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Abstract 1662: Dendrogenin A is a newly identified mammalian steroidal alkaloid that induced autophagic cell death in melanoma cells through an LXRbeta-, Nur77- and Nor1-dependent way

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.1662-1662

2013

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Abstract 956: The liver-X-receptor-α is involved in the induction by Tamoxifen of breast cancer cell differentiation and death

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.956-956

2012

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Dendrogenin_A : A Natural Liver X Receptor Modulator for the Treatment of Acute Myeloid Leukemia

Blood, 2014-12, Vol.124 (21), p.3767-3767

2014

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Abstract 938: Discovery of Dendrogenin A as the first endogenous alkylaminooxysterol present in mammals with potent cell differentiation and anticancer activity

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.938-938

2011

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Abstract 2918: Molecular identification of the cholesterol-5,6-epoxide hydrolase: A new target for selective estrogen receptor modulators and unsaturated fatty acids

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.2918-2918

2010

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Ligand-induced internalization of cholecystokinin receptors. Demonstration of the importance of the carboxyl terminus for ligand-induced internalization of the rat cholecystokinin type B receptor but not the type A receptor

The Journal of biological chemistry, 1997-07, Vol.272 (29), p.18179-18184

1997

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Arginine 336 and Asparagine 333 of the Human Cholecystokinin-A Receptor Binding Site Interact with the Penultimate Aspartic Acid and the C-terminal Amide of Cholecystokinin

The Journal of biological chemistry, 1999-07, Vol.274 (29), p.20457-20464

1999

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evidence for a direct inetraction between the penultimate aspartic acid of cholecystokinin and histidine 207, located in the second extracellular loop of the cholecystokinin B receptor

The Journal of biological chemistry, 1999, Vol.274 (33), p.23191-23197

1999

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Cholesterol and Cancer, in the Balance

The prototypical inhibitor of cholesterol esterification, Sah 58-035 [3-[decyldimethylsilyl]-n-[2-(4-methylphenyl)-1-phenylethyl]propanamide], is an agonist of estrogen receptors

Role of the Extracellular Domains of the Cholecystokinin Receptor in Agonist Binding

Arginine 197 of the cholecystokinin-A receptor binding site interacts with the sulfate of the peptide agonist cholecystokinin

Met-195 of the Cholecystokinin-A Receptor Interacts with the Sulfated Tyrosine of Cholecystokinin and Is Crucial for Receptor Transition to High Affinity State

A Segment of Five Amino Acids in the Second Extracellular Loop of the Cholecystokinin-B Receptor Is Essential for Selectivity of the Peptide Agonist Gastrin

Evidence for a Direct Interaction between the Penultimate Aspartic Acid of Cholecystokinin and Histidine 207, Located in the Second Extracellular Loop of the Cholecystokinin B Receptor

Dendrogenin A and B two new steroidal alkaloids increasing neural responsiveness in the deafened guinea pig

The Third Intracellular Loop of the Rat and Mouse Cholecystokinin-A Receptors Is Responsible for Different Patterns of Gene Activation

The Biologically Crucial C Terminus of Cholecystokinin and the Non-peptide Agonist SR-146,131 Share a Common Binding Site in the Human CCK1 Receptor

Abstract P3-05-12: Circulating oxysterol metabolites as potential new surrogate markers for hormonotherapy in patients with hormone receptor-positive breast cancer? A pilot study

Abstract 1165: Identification of a cholesterol onco-metabolite, promoter of tumor in breast cancers, and of the enzyme involved in its biosynthesis

Mutation of Asn-391 within the Conserved NPXXY Motif of the Cholecystokinin B Receptor Abolishes Gq Protein Activation without Affecting Its Association with the Receptor

Abstract 5238: Characterization of the enzyme generating the cholesterol metabolite and tumor suppressor dendrogenin A in the breast and its deregulations in breast cancer

Abstract 1884: 6-oxo-cholestan-3β,5α-diol (OCDO) is a metabolite produced in tumors by cholesterol epoxide hydrolase activity and a tumor promoter: OCDO inhibition contributes to the anti-tumor activity of tamoxifen and dendrogenin A

The biologically crucial C terminus of cholecystokinin and the non-peptide agonist SR-146,131 share a common binding site in the human CCK1 receptor. Evidence for a crucial role of Met-121 in the activation process

Ligand-induced Internalization of Cholecystokinin Receptors

Abstract 1662: Dendrogenin A is a newly identified mammalian steroidal alkaloid that induced autophagic cell death in melanoma cells through an LXRbeta-, Nur77- and Nor1-dependent way

Abstract 956: The liver-X-receptor-α is involved in the induction by Tamoxifen of breast cancer cell differentiation and death

Dendrogenin_A : A Natural Liver X Receptor Modulator for the Treatment of Acute Myeloid Leukemia

Abstract 938: Discovery of Dendrogenin A as the first endogenous alkylaminooxysterol present in mammals with potent cell differentiation and anticancer activity

Abstract 2918: Molecular identification of the cholesterol-5,6-epoxide hydrolase: A new target for selective estrogen receptor modulators and unsaturated fatty acids

Ligand-induced internalization of cholecystokinin receptors. Demonstration of the importance of the carboxyl terminus for ligand-induced internalization of the rat cholecystokinin type B receptor but not the type A receptor

Arginine 336 and Asparagine 333 of the Human Cholecystokinin-A Receptor Binding Site Interact with the Penultimate Aspartic Acid and the C-terminal Amide of Cholecystokinin

evidence for a direct inetraction between the penultimate aspartic acid of cholecystokinin and histidine 207, located in the second extracellular loop of the cholecystokinin B receptor

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