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Presenilin and Nicastrin Regulate Each Other and Determine Amyloid β-peptide Production via Complex Formation

Proceedings of the National Academy of Sciences - PNAS, 2002-06, Vol.99 (13), p.8666-8671

2002

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Die Bedeutung der DeGEval aus Sicht des Bundesministeriums für Wissenschaft, Forschung und Wirtschaft

Zeitschrift für evaluation, 2017-09, Vol.16 (2)

Winkler, Edith

2017

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Uncoupling Proteins 2 and 3 are Highly Active H+Transporters and Highly Nucleotide Sensitive When Activated by Coenzyme Q (Ubiquinone)

Proceedings of the National Academy of Sciences - PNAS, 2001-02, Vol.98 (4), p.1416-1421

2001

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Presenilin-1 Mutations of Leucine 166 Equally Affect the Generation of the Notch and APP Intracellular Domains Independent of Their Effect on Aβ42Production

Proceedings of the National Academy of Sciences - PNAS, 2002-06, Vol.99 (12), p.8025-8030

2002

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Intramembrane Proteolysis of GXGD-type Aspartyl Proteases Is Slowed by a Familial Alzheimer Disease-like Mutation

The Journal of biological chemistry, 2008-10, Vol.283 (44), p.30121-30128

2008

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Homodimerization Protects the Amyloid Precursor Protein C99 Fragment from Cleavage by γ‑Secretase

Biochemistry (Easton), 2015-10, Vol.54 (40), p.6149-6152

2015

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Validierung und Anerkennung non-formal und informell erworbener Kompetenzen an Hochschulen: Rahmenbedingungen, Erfahrungen und Herausforderungen

2022

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Effective sample preparation procedure for the analysis of free neutral steroids, free steroid acids and sterol sulfates in different tissues by GC–MS

The Journal of steroid biochemistry and molecular biology, 2021-07, Vol.211, p.105880-105880, Article 105880

2021

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Membrane lipid remodeling modulates γ-secretase processivity

The Journal of biological chemistry, 2023-04, Vol.299 (4), p.103027-103027, Article 103027

2023

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Uncoupling proteins: Martin Klingenberg's contributions for 40 years

Archives of biochemistry and biophysics, 2018-11, Vol.657, p.41-55

2018

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Photo-controlled delivery of very long chain fatty acids to cell membranes and modulation of membrane protein function

Biochimica et biophysica acta. Biomembranes, 2020-05, Vol.1862 (5), p.183200-183200, Article 183200

2020

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Chemical Cross-linking Provides a Model of the γ-Secretase Complex Subunit Architecture and Evidence for Close Proximity of the C-terminal Fragment of Presenilin with APH-1

The Journal of biological chemistry, 2008-12, Vol.283 (50), p.34677-34686

2008

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Reconstitution of γ-secretase activity

Nature cell biology, 2003-05, Vol.5 (5), p.486-488

2003

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β-Amyloid Precursor Protein Mutants Respond to γ-Secretase Modulators

The Journal of biological chemistry, 2010-06, Vol.285 (23), p.17798-17810

2010

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Coenzyme Q is an obligatory cofactor for uncoupling protein function

Nature (London), 2000-11, Vol.408 (6812), p.609-613

2000

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PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin

The Journal of biological chemistry, 2002-10, Vol.277 (42), p.39062-39065

2002

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Intramembrane Proteolysis of [Beta]-Amyloid Precursor Protein by [gamma]-Secretase Is an Unusually Slow Process

Biophysical journal, 2015-03, Vol.108 (5), p.1229

2015

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Purification, Pharmacological Modulation, and Biochemical Characterization of Interactors of Endogenous Human γ-Secretase

Biochemistry (Easton), 2009-02, Vol.48 (6), p.1183-1197

2009

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Bexarotene Binds to the Amyloid Precursor Protein Transmembrane Domain, Alters Its α-Helical Conformation, and Inhibits γ-Secretase Nonselectively in Liposomes

ACS chemical neuroscience, 2018-07, Vol.9 (7), p.1702-1713

2018

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The presenilin C-terminus is required for ER-retention, nicastrin-binding and γ-secretase activity

The EMBO journal, 2004-12, Vol.23 (24), p.4738-4748

2004

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Endoproteolysis of the ER Stress Transducer ATF6 in the Presence of Functionally Inactive Presenilins

Neurobiology of disease, 2001-08, Vol.8 (4), p.717-722

2001

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Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms

The Journal of neuroscience, 2010-06, Vol.30 (26), p.8974-8983

2010

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Chemical Cross-linking Provides a Model of the Î³-Secretase Complex Subunit Architecture and Evidence for Close Proximity of the C-terminal Fragment of Presenilin with APH-1

The Journal of biological chemistry, 2008-12, Vol.283 (50), p.34677

2008

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Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

Presenilin and Nicastrin Regulate Each Other and Determine Amyloid β-peptide Production via Complex Formation

Die Bedeutung der DeGEval aus Sicht des Bundesministeriums für Wissenschaft, Forschung und Wirtschaft

Uncoupling Proteins 2 and 3 are Highly Active H+Transporters and Highly Nucleotide Sensitive When Activated by Coenzyme Q (Ubiquinone)

Presenilin-1 Mutations of Leucine 166 Equally Affect the Generation of the Notch and APP Intracellular Domains Independent of Their Effect on Aβ42Production

Intramembrane Proteolysis of GXGD-type Aspartyl Proteases Is Slowed by a Familial Alzheimer Disease-like Mutation

Homodimerization Protects the Amyloid Precursor Protein C99 Fragment from Cleavage by γ‑Secretase

Validierung und Anerkennung non-formal und informell erworbener Kompetenzen an Hochschulen: Rahmenbedingungen, Erfahrungen und Herausforderungen

Effective sample preparation procedure for the analysis of free neutral steroids, free steroid acids and sterol sulfates in different tissues by GC–MS

Membrane lipid remodeling modulates γ-secretase processivity

Uncoupling proteins: Martin Klingenberg's contributions for 40 years

Photo-controlled delivery of very long chain fatty acids to cell membranes and modulation of membrane protein function

Chemical Cross-linking Provides a Model of the γ-Secretase Complex Subunit Architecture and Evidence for Close Proximity of the C-terminal Fragment of Presenilin with APH-1

Reconstitution of γ-secretase activity

β-Amyloid Precursor Protein Mutants Respond to γ-Secretase Modulators

Coenzyme Q is an obligatory cofactor for uncoupling protein function

PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin

Intramembrane Proteolysis of [Beta]-Amyloid Precursor Protein by [gamma]-Secretase Is an Unusually Slow Process

Purification, Pharmacological Modulation, and Biochemical Characterization of Interactors of Endogenous Human γ-Secretase

Microbiota-derived short chain fatty acids modulate microglia and promote A[beta] plaque deposition

Bexarotene Binds to the Amyloid Precursor Protein Transmembrane Domain, Alters Its α-Helical Conformation, and Inhibits γ-Secretase Nonselectively in Liposomes

The presenilin C-terminus is required for ER-retention, nicastrin-binding and γ-secretase activity

Endoproteolysis of the ER Stress Transducer ATF6 in the Presence of Functionally Inactive Presenilins

Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms

Chemical Cross-linking Provides a Model of the Î³-Secretase Complex Subunit Architecture and Evidence for Close Proximity of the C-terminal Fragment of Presenilin with APH-1

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