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UDP-glucuronosyltransferases

Current drug metabolism, 2000-09, Vol.1 (2), p.143-161

2000

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Mice Lacking Multidrug Resistance Protein 3 Show Altered Morphine Pharmacokinetics and Morphine-6-Glucuronide Antinociception

Proceedings of the National Academy of Sciences - PNAS, 2005-05, Vol.102 (20), p.7274-7279

2005

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Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

The Journal of clinical investigation, 1998-02, Vol.101 (4), p.847-854

1998

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Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3

Drug metabolism and disposition, 1998-06, Vol.26 (6), p.507

1998

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Expression of UDP-Glucuronosyltransferases (UGTs) 2B7 and 1A6 in the Human Brain and Identification of 5-Hydroxytryptamine as a Substrate

Archives of biochemistry and biophysics, 1999-05, Vol.365 (1), p.156-162

1999

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Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein

Drug metabolism and disposition, 1996-03, Vol.24 (3), p.356

1996

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Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7

The Journal of steroid biochemistry and molecular biology, 1999-07, Vol.70 (1), p.101-108

1999

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Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates

Drug metabolism and disposition, 1994-09, Vol.22 (5), p.799

1994

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Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides

Drug metabolism and disposition, 1995-03, Vol.23 (3), p.299

1995

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The toxicity of methanol

Life Sciences, 1991, Vol.48 (11), p.1031-1041

Tephly, Thomas R.

1991

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Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved

Carcinogenesis (New York), 1999-06, Vol.20 (6), p.1107-1114

1999

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Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteins

Drug metabolism and disposition, 1998-09, Vol.26 (9), p.860

1998

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Glucuronidation of Catechol Estrogens by Expressed Human UDP-Glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7

Toxicological sciences, 1998-09, Vol.45 (1), p.52-57

1998

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Cloning and Expression of Human UDP-Glucuronosyltransferase (UGT) 1A8

Archives of biochemistry and biophysics, 1998-08, Vol.356 (2), p.301-305

1998

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Analysis of Opioid Binding to UDP-Glucuronosyltransferase 2B7 Fusion Proteins Using Nuclear Magnetic Resonance Spectroscopy

Molecular pharmacology, 2001-06, Vol.59 (6), p.1464-1469

2001

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Comments on the purported generation of formaldehyde and adduct formation from the sweetener aspartame

Life sciences (1973), 1999, Vol.65 (13), p.PL157-PL160

Tephly, T.R.

1999

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Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds

Drug metabolism and disposition, 1997-02, Vol.25 (2), p.251

1997

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UDP-glucuronosyltransferases: a family of detoxifying enzymes

Trends in Pharmacological Sciences, 1990-07, Vol.11 (7), p.276-279

1990

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Immunohistochemical localization of UDP-glucuronosyltransferases in rat brain during early development

Drug metabolism and disposition, 1998-10, Vol.26 (10), p.1039

1998

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Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by rat UDP-glucuronosyltransferase 2B1

Drug metabolism and disposition, 1999-09, Vol.27 (9), p.1010

1999

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Inhibition and active sites of UDP-glucuronosyltransferases 2B7 and 1A1

Drug metabolism and disposition, 2002-12, Vol.30 (12), p.1364-1367

2002

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Folate and 10-Formyltetrahydrofolate Dehydrogenase in Human and Rat Retina: Relation to Methanol Toxicity

Toxicology and applied pharmacology, 1996-12, Vol.141 (2), p.373-381

1996

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Cloning and stable expression of a cDNA encoding a rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 1.1) that catalyzes the glucuronidation of opioids and bilirubin

Molecular pharmacology, 1995-06, Vol.47 (6), p.1101-1105

1995

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Symposium overview: Characterization of xenobiotic metabolizing enzyme function using heterologous expression systems

Toxicological sciences, 1999-04, Vol.48 (2), p.143-150

1999

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Studies on the role of folic acid and folate-dependent enzymes in human methanol poisoning

Molecular pharmacology, 1987-05, Vol.31 (5), p.557-561

1987

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UDP-glucuronosyltransferases

Mice Lacking Multidrug Resistance Protein 3 Show Altered Morphine Pharmacokinetics and Morphine-6-Glucuronide Antinociception

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3

Expression of UDP-Glucuronosyltransferases (UGTs) 2B7 and 1A6 in the Human Brain and Identification of 5-Hydroxytryptamine as a Substrate

Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein

Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7

Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates

Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides

The toxicity of methanol

Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved

Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteins

Glucuronidation of Catechol Estrogens by Expressed Human UDP-Glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7

Cloning and Expression of Human UDP-Glucuronosyltransferase (UGT) 1A8

Analysis of Opioid Binding to UDP-Glucuronosyltransferase 2B7 Fusion Proteins Using Nuclear Magnetic Resonance Spectroscopy

Comments on the purported generation of formaldehyde and adduct formation from the sweetener aspartame

Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds

UDP-glucuronosyltransferases: a family of detoxifying enzymes

Immunohistochemical localization of UDP-glucuronosyltransferases in rat brain during early development

Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by rat UDP-glucuronosyltransferase 2B1

Inhibition and active sites of UDP-glucuronosyltransferases 2B7 and 1A1

Folate and 10-Formyltetrahydrofolate Dehydrogenase in Human and Rat Retina: Relation to Methanol Toxicity

Cloning and stable expression of a cDNA encoding a rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 1.1) that catalyzes the glucuronidation of opioids and bilirubin

Symposium overview: Characterization of xenobiotic metabolizing enzyme function using heterologous expression systems

Studies on the role of folic acid and folate-dependent enzymes in human methanol poisoning

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