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Discovery and SAR of a Novel Selective and Orally Bioavailable Nonpeptide Classical Competitive Inhibitor Class of Protein-Tyrosine Phosphatase 1B

Journal of medicinal chemistry, 2002-09, Vol.45 (20), p.4443-4459

2002

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2-(Oxalylamino)-Benzoic Acid Is a General, Competitive Inhibitor of Protein-tyrosine Phosphatases

The Journal of biological chemistry, 2000-03, Vol.275 (10), p.7101-7108

2000

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Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog

Nature structural & molecular biology, 2003-01, Vol.10 (1), p.19-25

2003

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Crystal structure of the alkaline proteinase Savinase ™ from Bacillus lentus at 1.4 Å resolution

Journal of molecular biology, 1992-01, Vol.223 (2), p.427-445

1992

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Affinity purification of recombinant protein-tyrosine phosphatase 1B using a highly selective inhibitor

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004-01, Vol.799 (1), p.1-8

2004

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Characterization of recombinant murine factor VIIa and recombinant murine tissue factor: a human–murine species compatibility study

Thrombosis research, 2005, Vol.116 (1), p.75-85

2005

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Steric Hindrance as a Basis for Structure-Based Design of Selective Inhibitors of Protein-Tyrosine Phosphatases

Biochemistry (Easton), 2001-12, Vol.40 (49), p.14812-14820

2001

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Dipeptidyl peptidase 8 and 9: specificity and molecular characterization compared to dipeptidyl peptidase IV

Biochemical journal, 2006-02, Vol.396 (2), p.391-399

2006

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Synthesis of 2-amino-4h-thiazolo[5,4-b]indole and characterization of its colored conversion products with protein tyrosine phosphatase inhibitory activity

Journal of heterocyclic chemistry, 2001-05, Vol.38 (3), p.569-577

2001

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Residue 259 Is a Key Determinant of Substrate Specificity of Protein-tyrosine Phosphatases 1B and Î

The Journal of biological chemistry, 2000-06, Vol.275 (24), p.18201

2000

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Synthesis of 2‐amino‐4 h ‐thiazolo[5,4‐ b ]indole and characterization of its colored conversion products with protein tyrosine phosphatase inhibitory activity

Journal of heterocyclic chemistry, 2001-05, Vol.38 (3), p.569-577

2001

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Crystal structures of the alkaline proteases savinase and esperase from Bacillus lentus

Advances in experimental medicine and biology, 1996, Vol.379, p.49

1996

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pH dependence of the catalytic activity of a subtilisin-like proteinase

Advances in experimental medicine and biology, 1996, Vol.379, p.229

1996

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Cavity Mutants of Savinase

Journal of molecular biology, 1994-09, Vol.242 (3), p.193-202

1994

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X-Ray structure of the antibiotic bacitracin A

FEBS letters, 1991-07, Vol.285 (1), p.115-119

1991

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Crystallographic Studies of Savinase, a Subtilisin‐like Proteinase, at pH 10.5

European journal of biochemistry, 1994-09, Vol.224 (2), p.507-518

1994

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Crystallization and preliminary X-ray diffraction studies of an alkaline protease from Bacillus lentus

Journal of molecular biology, 1988-12, Vol.204 (3), p.803-804

1988

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Synthesis and Reactions of 2-Cyclopenten-1-ylmagnesium Chloride

Acta chemica Scandinavica (Copenhagen. 1989), 1966, Vol.20, p.2192-2194

1966

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Amino Acid and NMR Analysis of Oxidized Mucor miehei Rennet

Annals of the New York Academy of Sciences, 1984-12, Vol.434 (1), p.340-342

1984

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ChemInform Abstract: Synthesis of 2-Amino-4H-thiazolo[5,4-b]indole and Characterization of Its Colored Conversion Products with Protein Tyrosine Phosphatase Inhibitory Activity

ChemInform, 2001-10, Vol.32 (41), p.no-no

2001

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Practical approaches to chemical modification of enzymes for industrial use

Biochemical Society transactions, 1983-01, Vol.11 (1), p.20-21

Branner-Jørgensen, S

1983

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On the Mechanism of Protein Cross-Linking with Glutaral-Dehyde

Enzyme Engineering, 1978, p.393-394

1978

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Discovery and SAR of a Novel Selective and Orally Bioavailable Nonpeptide Classical Competitive Inhibitor Class of Protein-Tyrosine Phosphatase 1B

2-(Oxalylamino)-Benzoic Acid Is a General, Competitive Inhibitor of Protein-tyrosine Phosphatases

Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog

Crystal structure of the alkaline proteinase Savinase ™ from Bacillus lentus at 1.4 Å resolution

Affinity purification of recombinant protein-tyrosine phosphatase 1B using a highly selective inhibitor

Characterization of recombinant murine factor VIIa and recombinant murine tissue factor: a human–murine species compatibility study

Steric Hindrance as a Basis for Structure-Based Design of Selective Inhibitors of Protein-Tyrosine Phosphatases

Dipeptidyl peptidase 8 and 9: specificity and molecular characterization compared to dipeptidyl peptidase IV

Synthesis of 2-amino-4h-thiazolo[5,4-b]indole and characterization of its colored conversion products with protein tyrosine phosphatase inhibitory activity

Residue 259 Is a Key Determinant of Substrate Specificity of Protein-tyrosine Phosphatases 1B and Î

Synthesis of 2‐amino‐4 h ‐thiazolo[5,4‐ b ]indole and characterization of its colored conversion products with protein tyrosine phosphatase inhibitory activity

Crystal structures of the alkaline proteases savinase and esperase from Bacillus lentus

pH dependence of the catalytic activity of a subtilisin-like proteinase

Cavity Mutants of Savinase

X-Ray structure of the antibiotic bacitracin A

Crystallographic Studies of Savinase, a Subtilisin‐like Proteinase, at pH 10.5

Crystallization and preliminary X-ray diffraction studies of an alkaline protease from Bacillus lentus

Synthesis and Reactions of 2-Cyclopenten-1-ylmagnesium Chloride

Amino Acid and NMR Analysis of Oxidized Mucor miehei Rennet

ChemInform Abstract: Synthesis of 2-Amino-4H-thiazolo[5,4-b]indole and Characterization of Its Colored Conversion Products with Protein Tyrosine Phosphatase Inhibitory Activity

Practical approaches to chemical modification of enzymes for industrial use

On the Mechanism of Protein Cross-Linking with Glutaral-Dehyde

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