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Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models

Scientific reports, 2020-10, Vol.10 (1), p.17853-17853, Article 17853

2020

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Generation of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during Inflammation

Mediators of Inflammation, 2016-01, Vol.2016, p.1785021-10

2016

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Inflammation-induced lethargy is mediated by suppression of orexin neuron activity

The Journal of neuroscience, 2011-08, Vol.31 (31), p.11376-11386

2011

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Regulation of Human Endometrial Stromal Proliferation and Differentiation by C/EBPβ Involves Cyclin E-cdk2 and STAT3

Molecular endocrinology (Baltimore, Md.), 2012-12, Vol.26 (12), p.2016-2030

2012

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Enhancing Interleukin-6 and Interleukin-11 receptor cleavage

The international journal of biochemistry & cell biology, 2017-04, Vol.85, p.6-14

2017

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Differential Endometrial Gene Expression in Pregnant and Nonpregnant Sows

Biology of reproduction, 2010-08, Vol.83 (2), p.277-285

2010

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Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis

Gastroenterology (New York, N.Y. 1943), 2019-09, Vol.157 (3), p.777-792.e14

2019

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GM‐CSF and IL‐4 are not involved in IVIG‐mediated amelioration of ITP in mice: a role for IL‐11 cannot be ruled out

Clinical and experimental immunology, 2018-09, Vol.193 (3), p.293-301

2018

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The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement

The Journal of biological chemistry, 2020-06, Vol.295 (24), p.8285-8301

2020

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Fibroblast‐specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease

The FASEB journal, 2020-09, Vol.34 (9), p.11802-11815

2020

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IL-11Rα: a novel target for the treatment of osteosarcoma

Advances in experimental medicine and biology, 2014, Vol.804, p.285

Lewis, Valerae O

2014

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Sod1 deficiency reduces incubation time in mouse models of prion disease

PloS one, 2013-01, Vol.8 (1), p.e54454-e54454

2013

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IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts

Rheumatology (Oxford, England), 2021-12, Vol.60 (12), p.5820-5826

2021

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Rare and low-frequency coding variants alter human adult height

Nature (London), 2017-02, Vol.542 (7640), p.186-190

2017

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Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease

Nature communications, 2022-12, Vol.13 (1), p.7497-18, Article 7497

2022

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Host IL11 Signaling Suppresses CD4 + T cell-Mediated Antitumor Responses to Colon Cancer in Mice

Cancer immunology research, 2021-07, Vol.9 (7), p.735-747

2021

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Xenopus laevis il11ra.L is an experimentally proven interleukin-11 receptor component that is required for tadpole tail regeneration

Scientific reports, 2022-02, Vol.12 (1), p.1903-11, Article 1903

2022

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Targeting Interleukin-11 Receptor-α Impairs Human Endometrial Cancer Cell Proliferation and Invasion In Vitro and Reduces Tumor Growth and Metastasis In Vivo

Molecular cancer therapeutics, 2016-04, Vol.15 (4), p.720-730

2016

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Evolution of the phenotype of craniosynostosis with dental anomalies syndrome and report of IL11RA variant population frequencies in a Crouzon‐like autosomal recessive syndrome

American journal of medical genetics. Part A, 2019-04, Vol.179 (4), p.668-673

2019

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IL-11 Regulates Autoimmune Demyelination

The Journal of immunology (1950), 2009-10, Vol.183 (7), p.4229-4240

2009

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Enhancing antitumor immunity and achieving tumor eradication with IL11RA mRNA immunotherapy

International immunopharmacology, 2024-06, Vol.134, p.112205, Article 112205

2024

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The outcome of targeted NGS screening in patients with syndromic forms of sagittal and pansynostosis - IL11RA is an emerging core-gene for pansynostosis

European journal of medical genetics, 2022-05, Vol.65 (5), p.104476-104476, Article 104476

2022

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Interleukin-11 receptor α is overexpressed in human osteosarcoma, and near-infrared-labeled IL-11Rα imaging agent could detect osteosarcoma in mouse tumor xenografts

Tumor biology, 2015-04, Vol.36 (4), p.2369-2375

2015

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A Role for Transcription Factor STAT3 Signaling in Oncogene Smoothened-driven Carcinogenesis

The Journal of biological chemistry, 2012-11, Vol.287 (45), p.38356-38366

2012

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IL11 Antagonist Inhibits Uterine Stromal Differentiation, Causing Pregnancy Failure in Mice

Biology of reproduction, 2009-05, Vol.80 (5), p.920-927

2009

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Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models

Generation of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during Inflammation

Inflammation-induced lethargy is mediated by suppression of orexin neuron activity

Regulation of Human Endometrial Stromal Proliferation and Differentiation by C/EBPβ Involves Cyclin E-cdk2 and STAT3

Enhancing Interleukin-6 and Interleukin-11 receptor cleavage

Differential Endometrial Gene Expression in Pregnant and Nonpregnant Sows

Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis

GM‐CSF and IL‐4 are not involved in IVIG‐mediated amelioration of ITP in mice: a role for IL‐11 cannot be ruled out

The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement

Fibroblast‐specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease

IL-11Rα: a novel target for the treatment of osteosarcoma

Sod1 deficiency reduces incubation time in mouse models of prion disease

IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts

Rare and low-frequency coding variants alter human adult height

Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease

Host IL11 Signaling Suppresses CD4 + T cell-Mediated Antitumor Responses to Colon Cancer in Mice

Xenopus laevis il11ra.L is an experimentally proven interleukin-11 receptor component that is required for tadpole tail regeneration

Targeting Interleukin-11 Receptor-α Impairs Human Endometrial Cancer Cell Proliferation and Invasion In Vitro and Reduces Tumor Growth and Metastasis In Vivo

Evolution of the phenotype of craniosynostosis with dental anomalies syndrome and report of IL11RA variant population frequencies in a Crouzon‐like autosomal recessive syndrome

IL-11 Regulates Autoimmune Demyelination

Enhancing antitumor immunity and achieving tumor eradication with IL11RA mRNA immunotherapy

The outcome of targeted NGS screening in patients with syndromic forms of sagittal and pansynostosis - IL11RA is an emerging core-gene for pansynostosis

Interleukin-11 receptor α is overexpressed in human osteosarcoma, and near-infrared-labeled IL-11Rα imaging agent could detect osteosarcoma in mouse tumor xenografts

A Role for Transcription Factor STAT3 Signaling in Oncogene Smoothened-driven Carcinogenesis

IL11 Antagonist Inhibits Uterine Stromal Differentiation, Causing Pregnancy Failure in Mice

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