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Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics

PLoS biology, 2018-12, Vol.16 (12), p.e2006265

2018

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Development of Intrathecal AAV9 Gene Therapy for Giant Axonal Neuropathy

Molecular therapy. Methods & clinical development, 2018-06, Vol.9, p.160-171

2018

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The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

The Journal of clinical investigation, 2007-03, Vol.117 (3), p.648-658

2007

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Editorial: Personalized medicine for neuromuscular disorders

Frontiers in cell and developmental biology, 2023-11, Vol.11, p.1329048-1329048

2023

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Akt and CHIP Coregulate Tau Degradation through Coordinated Interactions

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (9), p.3622-3627

2008

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SLC13A5 Deficiency Disorder: From Genetics to Gene Therapy

Genes, 2022-09, Vol.13 (9), p.1655

2022

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Gene Therapy: Novel Approaches to Targeting Monogenic Epilepsies

Frontiers in neurology, 2022-06, Vol.13, p.805007-805007

2022

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Advancing the pathologic phenotype of giant axonal neuropathy: early involvement of the ocular lens

Orphanet journal of rare diseases, 2019-02, Vol.14 (1), p.27-27, Article 27

2019

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Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G

American journal of physiology. Renal physiology, 2007-10, Vol.293 (4), p.F1332-F1341

2007

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In vivo functional brain mapping in a conditional mouse model of human tauopathy (tauP301L) reveals reduced neural activity in memory formation structures

Molecular neurodegeneration, 2013-02, Vol.8 (1), p.9-9, Article 9

2013

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Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model

Molecular neurodegeneration, 2014-01, Vol.9 (1), p.8-8, Article 8

2014

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AAV9-mediated FIG4 delivery prolongs life span in Charcot-Marie-Tooth disease type 4J mouse model

The Journal of clinical investigation, 2021-06, Vol.131 (11), p.1-11

2021

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The prolyl hydroxylase oxygen-sensing pathway is cytoprotective and allows maintenance of mitochondrial membrane potential during metabolic inhibition

American Journal of Physiology: Cell Physiology, 2007-02, Vol.292 (2), p.C719-C728

2007

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Toward a translational gene therapy for mucolipidosis IV

Molecular therapy. Methods & clinical development, 2024-12, Vol.32 (4), p.101345, Article 101345

2024

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604. Comparison of Intra-Cisterna Magna and Lumbar Puncture Intrathecal Delivery of scAAV9 GeneTherapy for Giant Axonal Neuropathy

Molecular therapy, 2016-05, Vol.24, p.S239-S239

2016

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15. Development of Intrathecal scAAV9 Gene Therapy for Giant Axonal Neuropathy

Molecular therapy, 2015-05, Vol.23, p.S6-S7

2015

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Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G

American journal of physiology. Renal physiology, 2007, Vol.62 (4)

2007

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The prolyl hydroxylase oxygen-sensing pathway is cytoprotective and allows maintenance of mitochondrial membrane potential during metabolic inhibition : Mitochondrial modeling and function

American Journal of Physiology: Cell Physiology, 2007, Vol.61 (2)

2007

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Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection

Cell, 2021-04, Vol.184 (7), p.1804-1820.e16

2021

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Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression

Nature communications, 2023-08, Vol.14 (1), p.5211-5211, Article 5211

2023

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Rates of immune cell infiltration in patients with triple-negative breast cancer by molecular subtype

PloS one, 2018-10, Vol.13 (10), p.e0204513-e0204513

2018

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The beneficial endophyte Trichoderma hamatum isolate DIS 219b promotes growth and delays the onset of the drought response in Theobroma cacao

Journal of experimental botany, 2009-07, Vol.60 (11), p.3279-3295

2009

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Plant—soil feedbacks: connecting ecosystem ecology and evolution

Functional ecology, 2016-07, Vol.30 (7), p.1032-1042

2016

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Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics

Development of Intrathecal AAV9 Gene Therapy for Giant Axonal Neuropathy

The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

Editorial: Personalized medicine for neuromuscular disorders

Akt and CHIP Coregulate Tau Degradation through Coordinated Interactions

SLC13A5 Deficiency Disorder: From Genetics to Gene Therapy

Gene Therapy: Novel Approaches to Targeting Monogenic Epilepsies

Advancing the pathologic phenotype of giant axonal neuropathy: early involvement of the ocular lens

Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G

In vivo functional brain mapping in a conditional mouse model of human tauopathy (tauP301L) reveals reduced neural activity in memory formation structures

Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model

AAV9-mediated FIG4 delivery prolongs life span in Charcot-Marie-Tooth disease type 4J mouse model

The prolyl hydroxylase oxygen-sensing pathway is cytoprotective and allows maintenance of mitochondrial membrane potential during metabolic inhibition

Toward a translational gene therapy for mucolipidosis IV

604. Comparison of Intra-Cisterna Magna and Lumbar Puncture Intrathecal Delivery of scAAV9 GeneTherapy for Giant Axonal Neuropathy

15. Development of Intrathecal scAAV9 Gene Therapy for Giant Axonal Neuropathy

Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G

The prolyl hydroxylase oxygen-sensing pathway is cytoprotective and allows maintenance of mitochondrial membrane potential during metabolic inhibition : Mitochondrial modeling and function

Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection

Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression

Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

Rates of immune cell infiltration in patients with triple-negative breast cancer by molecular subtype

JIB-04 Has Broad-Spectrum Antiviral Activity and Inhibits SARS-CoV-2 Replication and Coronavirus Pathogenesis

The beneficial endophyte Trichoderma hamatum isolate DIS 219b promotes growth and delays the onset of the drought response in Theobroma cacao

Plant—soil feedbacks: connecting ecosystem ecology and evolution

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