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Intrinsic cytotoxicity and chemomodulatory actions of novel phenethylisothiocyanate sphingoid base derivatives in HL-60 human promyelocytic leukemia cells

The Journal of pharmacology and experimental therapeutics, 2004-05, Vol.309 (2), p.452-461

2004

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Role of sphingolipid-mediated cell death in neurodegenerative diseases

Journal of lipid research, 1998-01, Vol.39 (1), p.1-16

1998

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Induction of Apoptotic DNA Damage and Cell Death by Activation of the Sphingomyelin Pathway

Proceedings of the National Academy of Sciences - PNAS, 1994-01, Vol.91 (1), p.73-77

1994

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Protein kinase C targeting in antineoplastic treatment strategies

Investigational new drugs, 1999-08, Vol.17 (3), p.227-240

1999

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Coordinate Regulation of Stress- and Mitogen-Activated Protein Kinases in the Apoptotic Actions of Ceramide and Sphingosine

Molecular pharmacology, 1997-12, Vol.52 (6), p.935-947

1997

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Specific Inhibition of Stat5a/b Promotes Apoptosis of IL-2-Responsive Primary and Tumor-Derived Lymphoid Cells

The Journal of immunology (1950), 2003-10, Vol.171 (8), p.3919-3927

2003

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Differential regulation of the mitogen-activated protein and stress-activated protein kinase cascades by adrenergic agonists in quiescent and regenerating adult rat hepatocytes

Molecular and Cellular Biology, 1997-07, Vol.17 (7), p.3556-3565

1997

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Induction of Apoptosis and Potentiation of Ceramide-mediated Cytotoxicity by Sphingoid Bases in Human Myeloid Leukemia Cells

The Journal of biological chemistry, 1996-04, Vol.271 (14), p.8275-8284

1996

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The role of ceramide in the cellular response to cytotoxic agents

Current opinion in oncology, 1998-11, Vol.10 (6), p.552-559

1998

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Presence of a peptide component of thymosin fraction-5 manifesting discrete cytostatic properties in HL-60 human promyelocytic leukemia cells

International immunopharmacology, 2005-07, Vol.5 (7), p.1317-1329

2005

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Somatostatin and Gamma-Aminobutyric Acid Inhibit Interleukin-1β-Stimulated Release of Interleukin-6 from Rat C6 Glioma Cells

Neuroimmunomodulation, 2004-01, Vol.11 (5), p.332-340

2004

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Evidence that the apoptotic actions of etoposide are independent of c-Jun/activating protein-1-mediated transregulation

The Journal of pharmacology and experimental therapeutics, 1999-09, Vol.290 (3), p.1384

1999

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Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis

Nature (London), 1996-03, Vol.380 (6569), p.75-79

1996

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Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C

Cancer research (Chicago, Ill.), 1994-04, Vol.54 (7), p.1707-1714

1994

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Modulation of the expression of Bcl-2 and related proteins in human leukemia cells by protein kinase C activators: relationship to effects on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis

Cell death and differentiation, 1997-05, Vol.4 (4), p.294-303

1997

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Ceramide and the induction of apoptosis

Clinical cancer research, 1996, Vol.2 (1), p.1-6

1996

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Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells

The Journal of biological chemistry, 1994-12, Vol.269 (50), p.31685-31692

1994

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Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling

Molecular pharmacology, 1998-11, Vol.54 (5), p.844-856

1998

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Hepatocellular protein kinase C activation by bile acids: implications for regulation of cholesterol 7 alpha-hydroxylase

American journal of physiology: Gastrointestinal and liver physiology, 1996-08, Vol.271 (2 Pt 1), p.G293-G303

1996

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Modulation of drug-induced apoptosis by interruption of the protein kinase C signal transduction pathway : A new therapeutic strategy

Clinical cancer research, 1996-12, Vol.2 (12), p.1915-1920

1996

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Ceramide-driven stress signals in cancer and aging

Advances in Cell Aging and Gerontology, 2003, Vol.12, p.47-69

2003

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Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2

Molecular pharmacology, 1997-12, Vol.52 (6), p.1000-1009

1997

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Growth arrest and non-apoptotic cell death associated with the suppression of c- myc Expression in MCF-7 breast tumor cells following acute exposure to doxorubicin

Biochemical pharmacology, 1996-04, Vol.51 (7), p.931-940

1996

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Downregulation of δ CaM kinase II in human tumor cells

Biochimica et biophysica acta, 1999-10, Vol.1452 (1), p.1-11

1999

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Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[β- d-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells

Biochemical pharmacology, 1994-03, Vol.47 (5), p.839-852

1994

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Intrinsic cytotoxicity and chemomodulatory actions of novel phenethylisothiocyanate sphingoid base derivatives in HL-60 human promyelocytic leukemia cells

Role of sphingolipid-mediated cell death in neurodegenerative diseases

Induction of Apoptotic DNA Damage and Cell Death by Activation of the Sphingomyelin Pathway

Protein kinase C targeting in antineoplastic treatment strategies

Coordinate Regulation of Stress- and Mitogen-Activated Protein Kinases in the Apoptotic Actions of Ceramide and Sphingosine

Specific Inhibition of Stat5a/b Promotes Apoptosis of IL-2-Responsive Primary and Tumor-Derived Lymphoid Cells

Differential regulation of the mitogen-activated protein and stress-activated protein kinase cascades by adrenergic agonists in quiescent and regenerating adult rat hepatocytes

Induction of Apoptosis and Potentiation of Ceramide-mediated Cytotoxicity by Sphingoid Bases in Human Myeloid Leukemia Cells

The role of ceramide in the cellular response to cytotoxic agents

Presence of a peptide component of thymosin fraction-5 manifesting discrete cytostatic properties in HL-60 human promyelocytic leukemia cells

Somatostatin and Gamma-Aminobutyric Acid Inhibit Interleukin-1β-Stimulated Release of Interleukin-6 from Rat C6 Glioma Cells

Evidence that the apoptotic actions of etoposide are independent of c-Jun/activating protein-1-mediated transregulation

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis

Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C

Modulation of the expression of Bcl-2 and related proteins in human leukemia cells by protein kinase C activators: relationship to effects on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis

Ceramide and the induction of apoptosis

Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells

Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling

Hepatocellular protein kinase C activation by bile acids: implications for regulation of cholesterol 7 alpha-hydroxylase

Modulation of drug-induced apoptosis by interruption of the protein kinase C signal transduction pathway : A new therapeutic strategy

Ceramide-driven stress signals in cancer and aging

Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2

Growth arrest and non-apoptotic cell death associated with the suppression of c- myc Expression in MCF-7 breast tumor cells following acute exposure to doxorubicin

Downregulation of δ CaM kinase II in human tumor cells

Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[β- d-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells

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