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Generation of novel respiratory syncytial virus vaccine candidate antigens that can induce high levels of prefusion-specific antibodies

Journal of bioscience and bioengineering, 2024-08, Vol.138 (2), p.127-136

2024

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Mucosal delivery of a prefusogenic-F, glycoprotein, and matrix proteins-based virus-like particle respiratory syncytial virus vaccine induces protective immunity as evidenced by challenge studies in mice

Virology (New York, N.Y.), 2024-10, Vol.598, p.110194, Article 110194

2024

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Immunological Lessons from Respiratory Syncytial Virus Vaccine Development

Immunity (Cambridge, Mass.), 2019-09, Vol.51 (3), p.429-442

2019

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Formulation of the respiratory syncytial virus fusion protein with a polymer-based combination adjuvant promotes transient and local innate immune responses and leads to improved adaptive immunity

Vaccine, 2016-09, Vol.34 (42), p.5114-5124

2016

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Immunology of bovine respiratory syncytial virus in calves

Molecular immunology, 2015-07, Vol.66 (1), p.48-56

2015

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Novel antigens for RSV vaccines

Current opinion in immunology, 2015-08, Vol.35, p.30-38

2015

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A single, low dose of a cGMP recombinant BCG vaccine elicits protective T cell immunity against the human respiratory syncytial virus infection and prevents lung pathology in mice

Vaccine, 2017-02, Vol.35 (5), p.757-766

2017

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Combined virus-like particle and fusion protein-encoding DNA vaccination of cotton rats induces protection against respiratory syncytial virus without causing vaccine-enhanced disease

Virology (New York, N.Y.), 2016-07, Vol.494, p.215-224

2016

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Improved RSV preF protein vaccine quality and stability by elucidation of supercooling-induced aggregation phenomena

European journal of pharmaceutics and biopharmaceutics, 2024-10, Vol.203, p.114457, Article 114457

2024

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VLPs generated by the fusion of RSV-F or hMPV-F glycoprotein to HIV-Gag show improved immunogenicity and neutralizing response in mice

Vaccine, 2024-05, Vol.42 (15), p.3474-3485

2024

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Equivalent immunogenicity across three RSVpreF vaccine lots in healthy adults 18–49 years of age: Results of a randomized phase 3 study

Vaccine, 2024-05, Vol.42 (13), p.3172-3179

2024

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Efficacy and safety of respiratory syncytial virus prefusion F protein vaccines in adults

The Journal of infection, 2024-08, Vol.89 (2), p.106211, Article 106211

2024

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Meeting report: WHO consultation on Respiratory Syncytial Virus (RSV) vaccine development, Geneva, 25–26 April 2016

Vaccine, 2019-11, Vol.37 (50), p.7355-7362

2019

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A unique combination adjuvant modulates immune responses preventing vaccine-enhanced pulmonary histopathology after a single dose vaccination with fusion protein and challenge with respiratory syncytial virus

Virology (New York, N.Y.), 2019-08, Vol.534, p.1-13

2019

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Immunization with an adjuvanted low-energy electron irradiation inactivated respiratory syncytial virus vaccine shows immunoprotective activity in mice

Vaccine, 2018-03, Vol.36 (12), p.1561-1569

2018

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Recombinant live attenuated influenza vaccine viruses carrying CD8 T-cell epitopes of respiratory syncytial virus protect mice against both pathogens without inflammatory disease

Antiviral research, 2019-08, Vol.168, p.9-17

2019

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Recombinant influenza virus carrying the conserved domain of respiratory syncytial virus (RSV) G protein confers protection against RSV without inflammatory disease

Virology (New York, N.Y.), 2015-02, Vol.476, p.217-225

2015

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Enhanced immune responses and protection by vaccination with respiratory syncytial virus fusion protein formulated with CpG oligodeoxynucleotide and innate defense regulator peptide in polyphosphazene microparticles

Vaccine, 2012-07, Vol.30 (35), p.5206-5214

2012

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Animal models of respiratory syncytial virus infection

Vaccine, 2017-01, Vol.35 (3), p.469-480

Taylor, Geraldine

2017

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Maternal transfer of RSV immunity in cotton rats vaccinated during pregnancy

Vaccine, 2015-10, Vol.33 (41), p.5371-5379

2015

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A single intranasal immunization with a subunit vaccine formulation induces higher mucosal IgA production than live respiratory syncytial virus

Virology (New York, N.Y.), 2016-12, Vol.499, p.288-297

2016

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Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota

Journal of allergy and clinical immunology, 2017-10, Vol.140 (4), p.1068-1078.e6

2017

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Efficacy and safety of an intranasal virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice and cotton rats

Vaccine, 2013-04, Vol.31 (17), p.2169-2176

2013

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Chimeric virus-like particles containing a conserved region of the G protein in combination with a single peptide of the M2 protein confer protection against respiratory syncytial virus infection

Antiviral research, 2016-07, Vol.131, p.131-140

2016

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Recombinant influenza virus expressing a fusion protein neutralizing epitope of respiratory syncytial virus (RSV) confers protection without vaccine-enhanced RSV disease

Antiviral research, 2015-03, Vol.115, p.1-8

2015

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Generation of novel respiratory syncytial virus vaccine candidate antigens that can induce high levels of prefusion-specific antibodies

Mucosal delivery of a prefusogenic-F, glycoprotein, and matrix proteins-based virus-like particle respiratory syncytial virus vaccine induces protective immunity as evidenced by challenge studies in mice

Immunological Lessons from Respiratory Syncytial Virus Vaccine Development

Formulation of the respiratory syncytial virus fusion protein with a polymer-based combination adjuvant promotes transient and local innate immune responses and leads to improved adaptive immunity

Immunology of bovine respiratory syncytial virus in calves

Novel antigens for RSV vaccines

A single, low dose of a cGMP recombinant BCG vaccine elicits protective T cell immunity against the human respiratory syncytial virus infection and prevents lung pathology in mice

Combined virus-like particle and fusion protein-encoding DNA vaccination of cotton rats induces protection against respiratory syncytial virus without causing vaccine-enhanced disease

Improved RSV preF protein vaccine quality and stability by elucidation of supercooling-induced aggregation phenomena

VLPs generated by the fusion of RSV-F or hMPV-F glycoprotein to HIV-Gag show improved immunogenicity and neutralizing response in mice

Equivalent immunogenicity across three RSVpreF vaccine lots in healthy adults 18–49 years of age: Results of a randomized phase 3 study

Efficacy and safety of respiratory syncytial virus prefusion F protein vaccines in adults

Meeting report: WHO consultation on Respiratory Syncytial Virus (RSV) vaccine development, Geneva, 25–26 April 2016

A unique combination adjuvant modulates immune responses preventing vaccine-enhanced pulmonary histopathology after a single dose vaccination with fusion protein and challenge with respiratory syncytial virus

Immunization with an adjuvanted low-energy electron irradiation inactivated respiratory syncytial virus vaccine shows immunoprotective activity in mice

Recombinant live attenuated influenza vaccine viruses carrying CD8 T-cell epitopes of respiratory syncytial virus protect mice against both pathogens without inflammatory disease

Recombinant influenza virus carrying the conserved domain of respiratory syncytial virus (RSV) G protein confers protection against RSV without inflammatory disease

Enhanced immune responses and protection by vaccination with respiratory syncytial virus fusion protein formulated with CpG oligodeoxynucleotide and innate defense regulator peptide in polyphosphazene microparticles

Animal models of respiratory syncytial virus infection

Maternal transfer of RSV immunity in cotton rats vaccinated during pregnancy

A single intranasal immunization with a subunit vaccine formulation induces higher mucosal IgA production than live respiratory syncytial virus

Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota

Efficacy and safety of an intranasal virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice and cotton rats

Chimeric virus-like particles containing a conserved region of the G protein in combination with a single peptide of the M2 protein confer protection against respiratory syncytial virus infection

Recombinant influenza virus expressing a fusion protein neutralizing epitope of respiratory syncytial virus (RSV) confers protection without vaccine-enhanced RSV disease

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