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Arabidopsis Raf‐like kinases act as positive regulators of subclass III SnRK2 in osmostress signaling

The Plant journal : for cell and molecular biology, 2020-07, Vol.103 (2), p.634-644

2020

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A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants

Nature communications, 2020-01, Vol.11 (1), p.613-613, Article 613

2020

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Plant Raf-like kinase integrates abscisic acid and hyperosmotic stress signaling upstream of SNF1-related protein kinase2

Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (46), p.E6388-E6396

2015

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Role of Raf-like kinases in SnRK2 activation and osmotic stress response in plants

Nature communications, 2020-12, Vol.11 (1), p.6184-6184, Article 6184

2020

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{V600E} BRAF$is Associated with Disabled Feedback Inhibition of RAF–MEK Signaling and Elevated Transcriptional Output of the Pathway

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (11), p.4519-4524

2009

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G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

Nature communications, 2016-03, Vol.7 (1), p.10884-10884, Article 10884

2016

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Classical RAS proteins are not essential for paradoxical ERK activation induced by RAF inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2022-02, Vol.119 (5)

2022

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Consensus on the RAS dimerization hypothesis: Strong evidence for lipid-mediated clustering but not for G-domain-mediated interactions

Molecular cell, 2023-04, Vol.83 (8), p.1210-1215

2023

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Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (3), p.E317-E326

2017

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Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation

Development (Cambridge), 2020-09, Vol.147 (17)

2020

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Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (39), p.24258-24268

2020

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Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

The EMBO journal, 2010-03, Vol.29 (6), p.1091-1104

2010

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Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth

PloS one, 2014-03, Vol.9 (3), p.e92917-e92917

2014

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Plasma membrane nanoswitches generate high-fidelity Ras signal transduction

Nature cell biology, 2007-08, Vol.9 (8), p.905-914

2007

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Mechanisms of isoform-specific residue influence on GTP-bound HRas, KRas, and NRas

Biophysical journal, 2022-10, Vol.121 (19), p.3616-3629

2022

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Millisecond molecular dynamics simulations of KRas-dimer formation and interfaces

Biophysical journal, 2022-10, Vol.121 (19), p.3730-3744

2022

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Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate Transactivation

Angewandte Chemie (International ed.), 2016-01, Vol.55 (3), p.983-986

International ed. in English, 2016

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Relaxation oscillations and hierarchy of feedbacks in MAPK signaling

Scientific reports, 2017-01, Vol.7 (1), p.38244-38244, Article 38244

2017

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Two distinct modes of guidance signalling during collective migration of border cells

Nature, 2007-07, Vol.448 (7151), p.362-365

2007

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Intrinsic protein disorder in oncogenic KRAS signaling

Cellular and molecular life sciences : CMLS, 2017-09, Vol.74 (17), p.3245-3261

2017

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Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia

Oncogene, 2013-04, Vol.32 (15), p.1950-1958

2013

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A new regulatory mechanism for Raf kinase activation, retinoic acid-bound Crabp1

Scientific reports, 2019-07, Vol.9 (1), p.10929-12, Article 10929

2019

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Theoretical analysis reveals a role for RAF conformational autoinhibition in paradoxical activation

eLife, 2023-10, Vol.12

2023

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Cyr61 promotes epithelial-mesenchymal transition and tumor metastasis of osteosarcoma by Raf-1/MEK/ERK/Elk-1/TWIST-1 signaling pathway

Molecular cancer, 2014-10, Vol.13 (1), p.236-236

2014

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A Raf-like protein kinase BHP mediates blue light-dependent stomatal opening

Scientific reports, 2017-03, Vol.7 (1), p.45586-45586, Article 45586

2017

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Arabidopsis Raf‐like kinases act as positive regulators of subclass III SnRK2 in osmostress signaling

A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants

Plant Raf-like kinase integrates abscisic acid and hyperosmotic stress signaling upstream of SNF1-related protein kinase2

Role of Raf-like kinases in SnRK2 activation and osmotic stress response in plants

{V600E} BRAF$is Associated with Disabled Feedback Inhibition of RAF–MEK Signaling and Elevated Transcriptional Output of the Pathway

G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

Classical RAS proteins are not essential for paradoxical ERK activation induced by RAF inhibitors

Consensus on the RAS dimerization hypothesis: Strong evidence for lipid-mediated clustering but not for G-domain-mediated interactions

Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling

Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation

Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth

Plasma membrane nanoswitches generate high-fidelity Ras signal transduction

Mechanisms of isoform-specific residue influence on GTP-bound HRas, KRas, and NRas

Millisecond molecular dynamics simulations of KRas-dimer formation and interfaces

Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate Transactivation

Relaxation oscillations and hierarchy of feedbacks in MAPK signaling

Two distinct modes of guidance signalling during collective migration of border cells

Intrinsic protein disorder in oncogenic KRAS signaling

Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia

A new regulatory mechanism for Raf kinase activation, retinoic acid-bound Crabp1

Theoretical analysis reveals a role for RAF conformational autoinhibition in paradoxical activation

Cyr61 promotes epithelial-mesenchymal transition and tumor metastasis of osteosarcoma by Raf-1/MEK/ERK/Elk-1/TWIST-1 signaling pathway

A Raf-like protein kinase BHP mediates blue light-dependent stomatal opening

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