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Mucosal delivery of a prefusogenic-F, glycoprotein, and matrix proteins-based virus-like particle respiratory syncytial virus vaccine induces protective immunity as evidenced by challenge studies in mice

Virology (New York, N.Y.), 2024-10, Vol.598, p.110194, Article 110194

2024

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Formulation of the respiratory syncytial virus fusion protein with a polymer-based combination adjuvant promotes transient and local innate immune responses and leads to improved adaptive immunity

Vaccine, 2016-09, Vol.34 (42), p.5114-5124

2016

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A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

Nature communications, 2015-09, Vol.6 (1), p.8143-8143, Article 8143

2015

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Combined virus-like particle and fusion protein-encoding DNA vaccination of cotton rats induces protection against respiratory syncytial virus without causing vaccine-enhanced disease

Virology (New York, N.Y.), 2016-07, Vol.494, p.215-224

2016

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Exacerbated lung inflammation in offspring with high maternal antibody levels following secondary RSV exposure

Frontiers in immunology, 2024-04, Vol.15, p.1377374-1377374

2024

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A novel respiratory syncytial virus (RSV) F subunit vaccine adjuvanted with GLA-SE elicits robust protective TH1-type humoral and cellular immunity in rodent models

PloS one, 2015-03, Vol.10 (3), p.e0119509-e0119509

2015

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Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (52), p.20822-20827

2008

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Vitamin A deficiency impairs the immune response to intranasal vaccination and RSV infection in neonatal calves

Scientific reports, 2019-10, Vol.9 (1), p.15157-14, Article 15157

2019

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Lung ILC2s are activated in BALB/c mice born to immunized mothers despite complete protection against respiratory syncytial virus

Frontiers in immunology, 2024-05, Vol.15, p.1374818-1374818

2024

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Structure-Based Design and Antigenic Validation of Respiratory Syncytial Virus G Immunogens

Journal of virology, 2022-04, Vol.96 (7), p.e0220121

2022

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A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines

Nature medicine, 2006-08, Vol.12 (8), p.905-907

2006

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A Single-Dose Recombinant Parainfluenza Virus 5-Vectored Vaccine Expressing Respiratory Syncytial Virus (RSV) F or G Protein Protected Cotton Rats and African Green Monkeys from RSV Challenge

Journal of virology, 2017-06, Vol.91 (11)

2017

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Recombinant live attenuated influenza vaccine viruses carrying CD8 T-cell epitopes of respiratory syncytial virus protect mice against both pathogens without inflammatory disease

Antiviral research, 2019-08, Vol.168, p.9-17

2019

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Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes

The Journal of experimental medicine, 2015-05, Vol.212 (5), p.699-714

2015

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Mucosal Delivery of Recombinant Vesicular Stomatitis Virus Vectors Expressing Envelope Proteins of Respiratory Syncytial Virus Induces Protective Immunity in Cotton Rats

Journal of virology, 2021-02, Vol.95 (6)

2021

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Preclinical evaluation of bacterially produced RSV-G protein vaccine: Strong protection against RSV challenge in cotton rat model

Scientific reports, 2017-02, Vol.7 (1), p.42428-42428, Article 42428

2017

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Immunogenicity and protective capacity of a virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice

PloS one, 2012-05, Vol.7 (5), p.e36812-e36812

2012

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A novel inactivated intranasal respiratory syncytial virus vaccine promotes viral clearance without Th2 associated vaccine-enhanced disease

PloS one, 2011-07, Vol.6 (7), p.e21823

2011

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Structural Characterization and Modeling of a Respiratory Syncytial Virus Fusion Glycoprotein Nanoparticle Vaccine in Solution

Molecular pharmaceutics, 2021-01, Vol.18 (1), p.359-376

2021

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A Recombinant G Protein Plus Cyclosporine A-Based Respiratory Syncytial Virus Vaccine Elicits Humoral and Regulatory T Cell Responses against Infection without Vaccine-Enhanced Disease

The Journal of immunology (1950), 2016-02, Vol.196 (4), p.1721-1731

2016

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Animal models of respiratory syncytial virus infection

Vaccine, 2017-01, Vol.35 (3), p.469-480

Taylor, Geraldine

2017

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Dual proinflammatory and antiviral properties of pulmonary eosinophils in respiratory syncytial virus vaccine-enhanced disease

Journal of virology, 2015-02, Vol.89 (3), p.1564-1578

2015

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Maternal transfer of RSV immunity in cotton rats vaccinated during pregnancy

Vaccine, 2015-10, Vol.33 (41), p.5371-5379

2015

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Prefusion RSV F Immunization Elicits Th2-Mediated Lung Pathology in Mice When Formulated With a Th2 (but Not a Th1/Th2-Balanced) Adjuvant Despite Complete Viral Protection

Frontiers in immunology, 2020-07, Vol.11, p.1673-1673

2020

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Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma

Nature medicine, 2012-10, Vol.18 (10), p.1525-1530

2012

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Mucosal delivery of a prefusogenic-F, glycoprotein, and matrix proteins-based virus-like particle respiratory syncytial virus vaccine induces protective immunity as evidenced by challenge studies in mice

Formulation of the respiratory syncytial virus fusion protein with a polymer-based combination adjuvant promotes transient and local innate immune responses and leads to improved adaptive immunity

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

Combined virus-like particle and fusion protein-encoding DNA vaccination of cotton rats induces protection against respiratory syncytial virus without causing vaccine-enhanced disease

Exacerbated lung inflammation in offspring with high maternal antibody levels following secondary RSV exposure

A novel respiratory syncytial virus (RSV) F subunit vaccine adjuvanted with GLA-SE elicits robust protective TH1-type humoral and cellular immunity in rodent models

Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG

Vitamin A deficiency impairs the immune response to intranasal vaccination and RSV infection in neonatal calves

Lung ILC2s are activated in BALB/c mice born to immunized mothers despite complete protection against respiratory syncytial virus

Structure-Based Design and Antigenic Validation of Respiratory Syncytial Virus G Immunogens

A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines

A Single-Dose Recombinant Parainfluenza Virus 5-Vectored Vaccine Expressing Respiratory Syncytial Virus (RSV) F or G Protein Protected Cotton Rats and African Green Monkeys from RSV Challenge

Recombinant live attenuated influenza vaccine viruses carrying CD8 T-cell epitopes of respiratory syncytial virus protect mice against both pathogens without inflammatory disease

Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes

Mucosal Delivery of Recombinant Vesicular Stomatitis Virus Vectors Expressing Envelope Proteins of Respiratory Syncytial Virus Induces Protective Immunity in Cotton Rats

Preclinical evaluation of bacterially produced RSV-G protein vaccine: Strong protection against RSV challenge in cotton rat model

Immunogenicity and protective capacity of a virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice

A novel inactivated intranasal respiratory syncytial virus vaccine promotes viral clearance without Th2 associated vaccine-enhanced disease

Structural Characterization and Modeling of a Respiratory Syncytial Virus Fusion Glycoprotein Nanoparticle Vaccine in Solution

A Recombinant G Protein Plus Cyclosporine A-Based Respiratory Syncytial Virus Vaccine Elicits Humoral and Regulatory T Cell Responses against Infection without Vaccine-Enhanced Disease

Animal models of respiratory syncytial virus infection

Dual proinflammatory and antiviral properties of pulmonary eosinophils in respiratory syncytial virus vaccine-enhanced disease

Maternal transfer of RSV immunity in cotton rats vaccinated during pregnancy

Prefusion RSV F Immunization Elicits Th2-Mediated Lung Pathology in Mice When Formulated With a Th2 (but Not a Th1/Th2-Balanced) Adjuvant Despite Complete Viral Protection

Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma

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