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The Opportunities and Challenges of Peroxisome Proliferator-Activated Receptors Ligands in Clinical Drug Discovery and Development

International journal of molecular sciences, 2018-07, Vol.19 (8), p.2189

2018

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Melatonin prevents obesity through modulation of gut microbiota in mice

Journal of pineal research, 2017-05, Vol.62 (4), p.np-n/a

2017

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Environmental chemical TCPOBOP exposure alters milk liposomes and offspring growth trajectories in mice

Ecotoxicology and environmental safety, 2024-03, Vol.272, p.116061-116061, Article 116061

2024

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High-Protein Diet Induces Hyperuricemia in a New Animal Model for Studying Human Gout

International journal of molecular sciences, 2020-03, Vol.21 (6), p.2147

2020

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Celastrol inhibits store operated calcium entry and suppresses psoriasis

Frontiers in pharmacology, 2023-02, Vol.14, p.1111798-1111798

2023

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Melatonin Attenuates Dextran Sodium Sulfate Induced Colitis in Obese Mice

Pharmaceuticals (Basel, Switzerland), 2021-08, Vol.14 (8), p.822

2021

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Estrogen Deprivation and Inhibition of Breast Cancer Growth in Vivo through Activation of the Orphan Nuclear Receptor Liver X Receptor

Molecular endocrinology (Baltimore, Md.), 2007-08, Vol.21 (8), p.1781-1790

2007

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Activation of LXRs prevents bile acid toxicity and cholestasis in female mice

Hepatology (Baltimore, Md.), 2007-02, Vol.45 (2), p.422-432

2007

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Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization

Hepatology (Baltimore, Md.), 2008-04, Vol.47 (4), p.1331-1342

2008

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Activation of liver X receptor increases acetaminophen clearance and prevents its toxicity in mice

Hepatology (Baltimore, Md.), 2011-12, Vol.54 (6), p.2208-2217

2011

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Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

Gastroenterology (New York, N.Y. 1943), 2008-02, Vol.134 (2), p.556-567.e1

2008

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Preventive obesity agent montmorillonite adsorbs dietary lipids and enhances lipid excretion from the digestive tract

Scientific reports, 2016-02, Vol.6 (1), p.19659-19659, Article 19659

2016

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The CAR agonist TCPOBOP inhibits lipogenesis and promotes fibrosis in the mammary gland of adolescent female mice

Toxicology letters, 2018-06, Vol.290, p.29-35

2018

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Combination exposure of melamine and cyanuric acid is associated with polyuria and activation of NLRP3 inflammasome in rats

American journal of physiology. Renal physiology, 2018-08, Vol.315 (2), p.F199-F210

2018

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A functional cross-talk between liver X receptor-α and constitutive androstane receptor links lipogenesis and xenobiotic responses

Molecular pharmacology, 2010-10, Vol.78 (4), p.666-674

2010

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Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase

The Journal of biological chemistry, 2015-01, Vol.290 (1), p.241-241

2015

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HPRT1 activity loss is associated with resistance to thiopurine in ALL

Oncotarget, 2018-01, Vol.9 (2), p.2268-2278

2018

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p15RS Attenuates Wnt/β-Catenin Signaling by Disrupting β-Catenin·TCF4 Interaction

The Journal of biological chemistry, 2010-11, Vol.285 (45), p.34621-34631

2010

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Mature adipocytes observed to undergo reproliferation and polyploidy

FEBS open bio, 2017-05, Vol.7 (5), p.652-658

2017

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ROR[alpha] inhibits adipocyte-conditioned medium-induced colorectal cancer cell proliferation and migration and chick embryo chorioallantoic membrane angiopoiesis

American Journal of Physiology: Cell Physiology, 2015-03, Vol.308 (5), p.C385

2015

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Functional crosstalk of CAR-LXR and ROR-LXR in drug metabolism and lipid metabolism: Development of Novel Therapeutic Strategy by Regulating the Nuclear Hormone Receptors

Advanced drug delivery reviews, 2010, Vol.62 (13), p.1316-1321

2010

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Biology of PXR: role in drug-hormone interactions

EXCLI journal, 2014-01, Vol.13, p.728-739

2014

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Inhibition of adipocyte differentiation and adipogenesis by the traditional Chinese herb Sibiraea angustata

Experimental biology and medicine (Maywood, N.J.), 2010-12, Vol.235 (12), p.1442-1449

2010

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A Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic ResponsesS

Molecular pharmacology, 2010-10, Vol.78 (4), p.666-674

2010

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Activation of LXR Increases Acetaminophen Clearance and Prevents Its Toxicity

Hepatology (Baltimore, Md.), 2011-12, Vol.54 (6), p.2208-2217

2011

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The Opportunities and Challenges of Peroxisome Proliferator-Activated Receptors Ligands in Clinical Drug Discovery and Development

Melatonin prevents obesity through modulation of gut microbiota in mice

Environmental chemical TCPOBOP exposure alters milk liposomes and offspring growth trajectories in mice

High-Protein Diet Induces Hyperuricemia in a New Animal Model for Studying Human Gout

Celastrol inhibits store operated calcium entry and suppresses psoriasis

Melatonin Attenuates Dextran Sodium Sulfate Induced Colitis in Obese Mice

Estrogen Deprivation and Inhibition of Breast Cancer Growth in Vivo through Activation of the Orphan Nuclear Receptor Liver X Receptor

Activation of LXRs prevents bile acid toxicity and cholestasis in female mice

Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization

Activation of liver X receptor increases acetaminophen clearance and prevents its toxicity in mice

Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

Preventive obesity agent montmorillonite adsorbs dietary lipids and enhances lipid excretion from the digestive tract

The CAR agonist TCPOBOP inhibits lipogenesis and promotes fibrosis in the mammary gland of adolescent female mice

Combination exposure of melamine and cyanuric acid is associated with polyuria and activation of NLRP3 inflammasome in rats

A functional cross-talk between liver X receptor-α and constitutive androstane receptor links lipogenesis and xenobiotic responses

Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase

HPRT1 activity loss is associated with resistance to thiopurine in ALL

p15RS Attenuates Wnt/β-Catenin Signaling by Disrupting β-Catenin·TCF4 Interaction

Mature adipocytes observed to undergo reproliferation and polyploidy

ROR[alpha] inhibits adipocyte-conditioned medium-induced colorectal cancer cell proliferation and migration and chick embryo chorioallantoic membrane angiopoiesis

Functional crosstalk of CAR-LXR and ROR-LXR in drug metabolism and lipid metabolism: Development of Novel Therapeutic Strategy by Regulating the Nuclear Hormone Receptors

Biology of PXR: role in drug-hormone interactions

Inhibition of adipocyte differentiation and adipogenesis by the traditional Chinese herb Sibiraea angustata

A Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic ResponsesS

Activation of LXR Increases Acetaminophen Clearance and Prevents Its Toxicity

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