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Regulation of brain glucose transporters by glucose and oxygen deprivation

Metabolism, clinical and experimental, 1999-04, Vol.48 (4), p.422-431

1999

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Pharmacokinetics and metabolism of [14C]dichloroacetate in male Sprague-Dawley rats. Identification of glycine conjugates, including hippurate, as urinary metabolites of dichloroacetate

Drug metabolism and disposition, 1998-11, Vol.26 (11), p.1134

1998

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Plasmodium berghei Infection: Dichloroacetate Improves Survival in Rats with Lactic Acidosis

Experimental parasitology, 1995-06, Vol.80 (4), p.624-632

1995

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Ischemia induces a selective biphasic response in brain mitochondrial mRNA levels

Neuroreport, 1999-05, Vol.10 (7), p.1593-1598

1999

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A Controlled Clinical Trial of Dichloroacetate for Treatment of Lactic Acidosis in Adults

The New England journal of medicine, 1992-11, Vol.327 (22), p.1564-1569

1992

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Natural history and course of acquired lactic acidosis in adults

The American journal of medicine, 1994-07, Vol.97 (1), p.47-54

1994

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Peripheral Neuropathy in Rats Exposed to Dichloroacetate

Journal of neuropathology and experimental neurology, 2009-09, Vol.68 (9), p.985-993

2009

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40 THE NATURAL HISTORY OF CRYPTOGENIC CIRRHOSIS FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION: A HISTORICAL COHORT STUDY

Journal of investigative medicine, 2005-03, Vol.53 (2), p.S393-S394

2005

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Efficacy of Dichloroacetate as a Lactate-Lowering Drug

Journal of clinical pharmacology, 2003-07, Vol.43 (7), p.683-691

2003

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Regulation of rat liver hydroxymethylglutaryl coenzyme A reductase by a new class of noncompetitive inhibitors: effects of dichloroacetate and related carboxylic acids on enzyme activity

The Journal of clinical investigation, 1983-11, Vol.72 (5), p.1575-1585

1983

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Dichloroacetate derivatives. metabolic effects and pharmacodynamics in normal rats

Life sciences (1973), 1987-11, Vol.41 (18), p.2167-2176

1987

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Developmental pattern of 3-hydroxy-3-methylglutaryl coenzyme a reductase in the rat

Life sciences (1973), 1988, Vol.42 (8), p.943-947

1988

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Deficiencies of folate and vitamin B 6 exert distinct effects on homocysteine, serine, and methionine kinetics

American journal of physiology: endocrinology and metabolism, 2001-12, Vol.281 (6), p.E1182-E1190

2001

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Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents

Biochemical pharmacology, 2003-11, Vol.66 (10), p.2029-2038

2003

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DICHLOROACETATE IMPROVES PARAMETERS OF AEROBIC FUNCTION IN PATIENTS WITH DEFECTS IN MITOCHONDRIAL ENERGY METABOLISM

Medicine and science in sports and exercise, 2003-05, Vol.35 (Supplement 1), p.S97

2003

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Treatment of streptozotocin diabetes with di-isopropylammonium dichloroacetate (DIPA)

Diabetes (New York, N.Y.), 1974-03, Vol.23 (3), p.179-182

1974

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Chronic toxicity of dichloroacetate: Possible relation to thiamine deficiency in rats

Fundamental and applied toxicology, 1990-02, Vol.14 (2), p.327-337

1990

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Prolonged hypolactatemia and increased total pyruvate dehydrogenase activity by dichloroacetate

Biochemical pharmacology, 1982-04, Vol.31 (7), p.1295-1300

1982

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Development of an Oral Drug Formulation for Dichloroacetate and Thiamine

Drug development and industrial pharmacy, 1994, Vol.20 (15), p.2425-2437

1994

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Effect of dichloroacetate on gluconeogenesis in isolated rat hepatocytes

Metabolism, clinical and experimental, 1977-02, Vol.26 (2), p.107-116

Stacpoole, Peter W.

1977

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Regulation of 3-hydroxy-3-methylglutaryl: coenzyme A reductase activity and cholesterol biosynthesis by guanabenz

Coronary artery disease, 1990-07, Vol.1 (4), p.477-482

1990

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Diisopropylammonium dichloroacetate (DIPA): reversible antagonism towards smooth muscle stimulants and inhibition of acetylcholinesterase in the isolated guinea pig ileum

Research communications in chemical pathology and pharmacology, 1971-07, Vol.2 (4), p.439

1971

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Methylphenidate Does Not Improve Cognitive Function in Healthy Sleep-Deprived Young Adults

Journal of investigative medicine, 2004-04, Vol.52 (3), p.192

2004

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Gene Therapy for Pyruvate Dehydrogenase E1α Deficiency Using Recombinant Adeno-Associated Virus 2 (rAAV2) Vectors

Molecular therapy, 2002-09, Vol.6 (3), p.394-399

2002

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Dietary carbohydrate decreases 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and cholesterol synthesis in rat liver

Biochemical and biophysical research communications, 1983-06, Vol.113 (3), p.888-894

1983

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Regulation of brain glucose transporters by glucose and oxygen deprivation

Pharmacokinetics and metabolism of [14C]dichloroacetate in male Sprague-Dawley rats. Identification of glycine conjugates, including hippurate, as urinary metabolites of dichloroacetate

Plasmodium berghei Infection: Dichloroacetate Improves Survival in Rats with Lactic Acidosis

Ischemia induces a selective biphasic response in brain mitochondrial mRNA levels

A Controlled Clinical Trial of Dichloroacetate for Treatment of Lactic Acidosis in Adults

Natural history and course of acquired lactic acidosis in adults

Peripheral Neuropathy in Rats Exposed to Dichloroacetate

40 THE NATURAL HISTORY OF CRYPTOGENIC CIRRHOSIS FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION: A HISTORICAL COHORT STUDY

Efficacy of Dichloroacetate as a Lactate-Lowering Drug

Regulation of rat liver hydroxymethylglutaryl coenzyme A reductase by a new class of noncompetitive inhibitors: effects of dichloroacetate and related carboxylic acids on enzyme activity

Dichloroacetate derivatives. metabolic effects and pharmacodynamics in normal rats

Developmental pattern of 3-hydroxy-3-methylglutaryl coenzyme a reductase in the rat

Deficiencies of folate and vitamin B 6 exert distinct effects on homocysteine, serine, and methionine kinetics

Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents

DICHLOROACETATE IMPROVES PARAMETERS OF AEROBIC FUNCTION IN PATIENTS WITH DEFECTS IN MITOCHONDRIAL ENERGY METABOLISM

Treatment of streptozotocin diabetes with di-isopropylammonium dichloroacetate (DIPA)

Chronic toxicity of dichloroacetate: Possible relation to thiamine deficiency in rats

Prolonged hypolactatemia and increased total pyruvate dehydrogenase activity by dichloroacetate

Development of an Oral Drug Formulation for Dichloroacetate and Thiamine

Effect of dichloroacetate on gluconeogenesis in isolated rat hepatocytes

Regulation of 3-hydroxy-3-methylglutaryl: coenzyme A reductase activity and cholesterol biosynthesis by guanabenz

Diisopropylammonium dichloroacetate (DIPA): reversible antagonism towards smooth muscle stimulants and inhibition of acetylcholinesterase in the isolated guinea pig ileum

Methylphenidate Does Not Improve Cognitive Function in Healthy Sleep-Deprived Young Adults

Gene Therapy for Pyruvate Dehydrogenase E1α Deficiency Using Recombinant Adeno-Associated Virus 2 (rAAV2) Vectors

Dietary carbohydrate decreases 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and cholesterol synthesis in rat liver

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