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Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice

Nucleic acids research, 2012-07, Vol.40 (13), p.6016-6025

2012

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The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice

The Journal of experimental medicine, 2006-09, Vol.203 (9), p.2085-2094

2006

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Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1α (eEF1A)

Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (45), p.18366-18371

2011

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Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase

Nature (London), 2002-09, Vol.419 (6902), p.43-48

2002

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Deficiency in APOBEC2 Leads to a Shift in Muscle Fiber Type, Diminished Body Mass, and Myopathy

The Journal of biological chemistry, 2010-03, Vol.285 (10), p.7111-7118

2010

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Mouse APOBEC3 Restricts Friend Leukemia Virus Infection and Pathogenesis In Vivo

Journal of Virology, 2008-11, Vol.82 (22), p.10998-11008

2008

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The AKV Murine Leukemia Virus Is Restricted and Hypermutated by Mouse APOBEC3

Journal of Virology, 2009-11, Vol.83 (22), p.11550-11559

2009

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Affinity Dependence of the B Cell Response to Antigen: A Threshold, a Ceiling, and the Importance of Off-Rate

Immunity (Cambridge, Mass.), 1998-06, Vol.8 (6), p.751-759

1998

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In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

The Journal of biological chemistry, 2003-05, Vol.278 (22), p.19583-19586

2003

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B cells extract and present immobilized antigen: implications for affinity discrimination

The EMBO journal, 2000-02, Vol.19 (4), p.513-520

2000

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Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation

European journal of immunology, 2014-07, Vol.44 (7), p.1925-1935

2014

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Hyperresponsive B Cells in CD22-Deficient Mice

Science (American Association for the Advancement of Science), 1996-11, Vol.274 (5288), p.798-801

1996

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Mismatch Recognition and Uracil Excision Provide Complementary Paths to Both Ig Switching and the A/T-Focused Phase of Somatic Mutation

Molecular cell, 2004-10, Vol.16 (2), p.163-171

2004

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Both DNA Strands of Antibody Genes are Hypermutation Targets

Proceedings of the National Academy of Sciences - PNAS, 1998-07, Vol.95 (15), p.8791-8794

1998

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Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID‐mediated deoxycytidine deamination

European journal of immunology, 2004-02, Vol.34 (2), p.504-508

2004

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RNA Editing Enzyme APOBEC1 and Some of Its Homologs Can Act as DNA Mutators

Molecular cell, 2002-11, Vol.10 (5), p.1247-1253

2002

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Targeted Gene Disruption Reveals a Role for Natural Secretory IgM in the Maturation of the Primary Immune Response

Proceedings of the National Academy of Sciences - PNAS, 1998-08, Vol.95 (17), p.10089-10093

1998

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Immunoglobulin Isotype Switching Is Inhibited and Somatic Hypermutation Perturbed in UNG-Deficient Mice

Current biology, 2002-10, Vol.12 (20), p.1748-1755

2002

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Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants

Cancer research (Chicago, Ill.), 2008-06, Vol.68 (12), p.4571-4579

2008

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Deficiency in spliceosome-associated factor CTNNBL1 does not affect ongoing cell cycling but delays exit from quiescence and results in embryonic lethality in mice

Cell cycle (Georgetown, Tex.), 2013-03, Vol.12 (5), p.732-742

2013

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SOMATIC HYPERMUTATION OF IMMUNOGLOBULIN GENES

Annual review of immunology, 1996-01, Vol.14 (1), p.441-457

1996

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Somatic hypermutation at A·T pairs: polymerase error versus dUTP incorporation

Nature reviews. Immunology, 2005-02, Vol.5 (2), p.171-178

2005

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Hot Spot Focusing of Somatic Hypermutation in MSH2-Deficient Mice Suggests Two Stages of Mutational Targeting

Immunity (Cambridge, Mass.), 1998-07, Vol.9 (1), p.135-141

1998

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Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies

The Journal of experimental medicine, 2000-04, Vol.191 (7), p.1253-1258

2000

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A high-throughput assay for DNA deaminases

Methods in molecular biology (Clifton, N.J.), 2011, Vol.718, p.171

2011

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Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice

The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice

Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1α (eEF1A)

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase

Deficiency in APOBEC2 Leads to a Shift in Muscle Fiber Type, Diminished Body Mass, and Myopathy

Mouse APOBEC3 Restricts Friend Leukemia Virus Infection and Pathogenesis In Vivo

The AKV Murine Leukemia Virus Is Restricted and Hypermutated by Mouse APOBEC3

Affinity Dependence of the B Cell Response to Antigen: A Threshold, a Ceiling, and the Importance of Off-Rate

In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

B cells extract and present immobilized antigen: implications for affinity discrimination

Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation

Hyperresponsive B Cells in CD22-Deficient Mice

Mismatch Recognition and Uracil Excision Provide Complementary Paths to Both Ig Switching and the A/T-Focused Phase of Somatic Mutation

Both DNA Strands of Antibody Genes are Hypermutation Targets

Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID‐mediated deoxycytidine deamination

RNA Editing Enzyme APOBEC1 and Some of Its Homologs Can Act as DNA Mutators

Targeted Gene Disruption Reveals a Role for Natural Secretory IgM in the Maturation of the Primary Immune Response

Immunoglobulin Isotype Switching Is Inhibited and Somatic Hypermutation Perturbed in UNG-Deficient Mice

Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants

Deficiency in spliceosome-associated factor CTNNBL1 does not affect ongoing cell cycling but delays exit from quiescence and results in embryonic lethality in mice

SOMATIC HYPERMUTATION OF IMMUNOGLOBULIN GENES

Somatic hypermutation at A·T pairs: polymerase error versus dUTP incorporation

Hot Spot Focusing of Somatic Hypermutation in MSH2-Deficient Mice Suggests Two Stages of Mutational Targeting

Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies

A high-throughput assay for DNA deaminases

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