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Ageing and rejuvenation of tissue stem cells and their niches

Nature reviews. Molecular cell biology, 2023-01, Vol.24 (1), p.45

2023

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Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal

Cell stem cell, 2014-05, Vol.14 (5), p.673-688

2014

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The push and pull of DNA methylation

Science (American Association for the Advancement of Science), 2021-04, Vol.372 (6538), p.128-129

2021

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DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

Nature genetics, 2016-09, Vol.48 (9), p.1014-1023

2016

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Dnmt3a and Dnmt3b Have Overlapping and Distinct Functions in Hematopoietic Stem Cells

Cell stem cell, 2014-09, Vol.15 (3), p.350-364

2014

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Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing

Blood, 2012-03, Vol.119 (11), p.2500-2509

2012

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Less Is More: Unveiling the Functional Core of Hematopoietic Stem Cells through Knockout Mice

Cell stem cell, 2012-09, Vol.11 (3), p.302-317

2012

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Distinct Hematopoietic Stem Cell Subtypes Are Differentially Regulated by TGF-β1

Cell stem cell, 2010-03, Vol.6 (3), p.265-278

2010

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Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation

Blood, 2015-01, Vol.125 (4), p.629-638

2015

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Long Non-Coding RNAs Control Hematopoietic Stem Cell Function

Cell stem cell, 2015-04, Vol.16 (4), p.426-438

2015

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A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells

Blood, 2013-12, Vol.122 (25), p.4086-4089

2013

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Acute loss of TET function results in aggressive myeloid cancer in mice

Nature communications, 2015-11, Vol.6 (1), p.10071-10071, Article 10071

2015

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It’s All About MEis: Menin-MLL Inhibition Eradicates NPM1-Mutated and MLL-Rearranged Acute Leukemias in Mice

Cancer cell, 2020-03, Vol.37 (3), p.267-269

2020

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Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo

Cell reports (Cambridge), 2018-04, Vol.23 (1), p.1-10

2018

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DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells

Genome Biology, 2018-07, Vol.19 (1), p.88-15, Article 88

2018

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Oncometabolite D-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (37), p.10436-10441

2016

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Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection

Nature (London), 2010-06, Vol.465 (7299), p.793-797

2010

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New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells

Experimental hematology, 2014-08, Vol.42 (8), p.609-617

2014

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Promotion of reprogramming to ground state pluripotency by signal inhibition

PLoS biology, 2008-10, Vol.6 (10), p.e253-e253

2008

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Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells

PLoS biology, 2009-07, Vol.7 (7), p.e1000149-e1000149

2009

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Ten-Eleven Translocation 1 (Tet1) Is Regulated by O-Linked N-Acetylglucosamine Transferase (Ogt) for Target Gene Repression in Mouse Embryonic Stem Cells

The Journal of biological chemistry, 2013-07, Vol.288 (29), p.20776-20784

2013

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Where There’s Smoke, There’s Fire: Inflammation Drives MDS

Trends in immunology, 2020-07, Vol.41 (7), p.558-560

2020

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Parental Permissions: H19 and Keeping the Stem Cell Progeny under Control

Cell stem cell, 2013-08, Vol.13 (2), p.137-138

Goodell, Margaret A.

2013

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A gallon of sweat to make a pint of blood

The Journal of experimental medicine, 2014-06, Vol.211 (7), p.1271-1272

Goodell, Margaret A

2014

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The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development

Nature genetics, 2022-05, Vol.54 (5), p.625-636

2022

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Ageing and rejuvenation of tissue stem cells and their niches

Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal

The push and pull of DNA methylation

DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

Dnmt3a and Dnmt3b Have Overlapping and Distinct Functions in Hematopoietic Stem Cells

Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing

Less Is More: Unveiling the Functional Core of Hematopoietic Stem Cells through Knockout Mice

Distinct Hematopoietic Stem Cell Subtypes Are Differentially Regulated by TGF-β1

Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation

Long Non-Coding RNAs Control Hematopoietic Stem Cell Function

A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells

Acute loss of TET function results in aggressive myeloid cancer in mice

It’s All About MEis: Menin-MLL Inhibition Eradicates NPM1-Mutated and MLL-Rearranged Acute Leukemias in Mice

Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo

DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells

Oncometabolite D-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart

Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection

New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells

Promotion of reprogramming to ground state pluripotency by signal inhibition

Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells

Ten-Eleven Translocation 1 (Tet1) Is Regulated by O-Linked N-Acetylglucosamine Transferase (Ogt) for Target Gene Repression in Mouse Embryonic Stem Cells

Where There’s Smoke, There’s Fire: Inflammation Drives MDS

Parental Permissions: H19 and Keeping the Stem Cell Progeny under Control

A gallon of sweat to make a pint of blood

The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development

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