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The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

International journal of molecular sciences, 2019-01, Vol.20 (1), p.81

2019

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Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12550

2023

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Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice

Molecular neurodegeneration, 2020-07, Vol.15 (1), p.41-21, Article 41

2020

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APOEε4 and risk of Alzheimer's disease - time to move forward

Frontiers in neuroscience, 2023-05, Vol.17, p.1195724-1195724

2023

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Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic

PloS one, 2013-02, Vol.8 (2), p.e53478

2013

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Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer’s model mice

Scientific reports, 2017-06, Vol.7 (1), p.4307-13, Article 4307

2017

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RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment

Neurobiology of disease, 2015-10, Vol.82, p.132-140

2015

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Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration

Neurobiology of disease, 2014-03, Vol.63, p.107-114

2014

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Genome-wide alteration of histone methylation profiles associated with cognitive changes in response to developmental arsenic exposure in mice

Toxicology reports, 2022-01, Vol.9, p.393-403

2022

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Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles

Nature aging, 2021-12, Vol.1 (12), p.1148

2021

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Apolipoprotein A-I Deficiency Increases Cerebral Amyloid Angiopathy and Cognitive Deficits in APP/PS1ΔE9 Mice

The Journal of biological chemistry, 2010-11, Vol.285 (47), p.36945-36957

2010

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Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924-924

2013

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Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice

Biochimica et biophysica acta. Molecular basis of disease, 2018-01, Vol.1864 (1), p.152-161

2018

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Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles

Nature aging, 2021-12, Vol.1 (12), p.1148-1161

2021

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Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice

Brain (London, England : 1878), 2015-12, Vol.138 (Pt 12), p.3699-3715

2015

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Improvement of memory deficits and amyloid-β clearance in aged APP23 mice treated with a combination of anti-amyloid-β antibody and LXR agonist

Journal of Alzheimer's disease, 2014-01, Vol.41 (2), p.535-549

2014

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Selective lesion of septal cholinergic neurons in rats impairs acquisition of a delayed matching to position T-maze task by delaying the shift from a response to a place strategy

Brain research bulletin, 2008-12, Vol.77 (6), p.356-360

2008

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HIGH-FAT DIET AFFECTS INFLAMMATION AND INCREASES TREM2 LEVEL IN APP MICE

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P655-P655

2016

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Memory deficits in APP23/Abca1+/- mice correlate with the level of Aβ oligomers

ASN neuro, 2009-04, Vol.1 (2), p.AN20090015

2009

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IMPACT OF APOE POLYMORPHISMS ON AMYLOID-BETA OLIGOMERIZATION AND ASSOCIATED COGNITIVE DECLINE

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P1038-P1039

2016

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Comment on: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924-92c

2013

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snoRNAs in plasma extracellular vesicles of AD patients are differentially associated with APOE genotype

Alzheimer's & dementia, 2021-12, Vol.17 (S4), p.n/a

2021

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Neural responses to peripheral infection in Alzheimer’s disease model mice

Alzheimer's & dementia, 2023-12, Vol.19 (S13), p.n/a

2023

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Aversive stimulus attenuates impairment of acquisition in a delayed match to position T-maze task caused by a selective lesion of septo-hippocampal cholinergic projections

Brain research bulletin, 2006-05, Vol.69 (6), p.660-665

2006

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Sex‐specific decoupling of cerebral blood flow and glucose metabolism in Alzheimer’s disease mouse model

Alzheimer's & dementia, 2022-12, Vol.18 (S6), p.n/a

2022

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The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice

Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice

APOEε4 and risk of Alzheimer's disease - time to move forward

Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic

Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer’s model mice

RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment

Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration

Genome-wide alteration of histone methylation profiles associated with cognitive changes in response to developmental arsenic exposure in mice

Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles

Apolipoprotein A-I Deficiency Increases Cerebral Amyloid Angiopathy and Cognitive Deficits in APP/PS1ΔE9 Mice

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice

Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles

Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice

Improvement of memory deficits and amyloid-β clearance in aged APP23 mice treated with a combination of anti-amyloid-β antibody and LXR agonist

Selective lesion of septal cholinergic neurons in rats impairs acquisition of a delayed matching to position T-maze task by delaying the shift from a response to a place strategy

HIGH-FAT DIET AFFECTS INFLAMMATION AND INCREASES TREM2 LEVEL IN APP MICE

Memory deficits in APP23/Abca1+/- mice correlate with the level of Aβ oligomers

IMPACT OF APOE POLYMORPHISMS ON AMYLOID-BETA OLIGOMERIZATION AND ASSOCIATED COGNITIVE DECLINE

Comment on: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

snoRNAs in plasma extracellular vesicles of AD patients are differentially associated with APOE genotype

Neural responses to peripheral infection in Alzheimer’s disease model mice

Aversive stimulus attenuates impairment of acquisition in a delayed match to position T-maze task caused by a selective lesion of septo-hippocampal cholinergic projections

Sex‐specific decoupling of cerebral blood flow and glucose metabolism in Alzheimer’s disease mouse model

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