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My Uncle Charlie

Journal of virology, 2023-01, Vol.97 (1), p.e0186622-e0186622

2023

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Global CNS Transduction of Adult Mice by Intravenously Delivered rAAVrh.8 and rAAVrh.10 and Nonhuman Primates by rAAVrh.10

Molecular therapy, 2014-07, Vol.22 (7), p.1299-1309

2014

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ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge

PLoS pathogens, 2012, Vol.8 (8), p.e1002890

2012

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Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies

Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.16068-16068, Article 16068

2016

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Vaccine protection against SIVmac239 acquisition

Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (5), p.1739-1744

2019

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High concordance of ELISA and neutralization assays allows for the detection of antibodies to individual AAV serotypes

Molecular therapy. Methods & clinical development, 2022-03, Vol.24, p.199-206

2022

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Comparative Characterization of Transfection- and Infection-Derived Simian Immunodeficiency Virus Challenge Stocks for In Vivo Nonhuman Primate Studies

Journal of Virology, 2013-04, Vol.87 (8), p.4584-4595

2013

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Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection

PLoS pathogens, 2016-12, Vol.12 (12), p.e1006104

2016

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Liver-Directed but Not Muscle-Directed AAV-Antibody Gene Transfer Limits Humoral Immune Responses in Rhesus Monkeys

Molecular therapy. Methods & clinical development, 2020-03, Vol.16, p.94-102

2020

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SIV vpx is essential for macrophage infection but not for development of AIDS

PloS one, 2014-01, Vol.9 (1), p.e84463

2014

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Glycoengineering of AAV-delivered monoclonal antibodies yields increased ADCC activity

Molecular therapy. Methods & clinical development, 2021-03, Vol.20, p.204-217

2021

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MHC heterozygote advantage in simian immunodeficiency virus-infected Mauritian cynomolgus macaques

Science translational medicine, 2010-03, Vol.2 (22), p.22ra18

2010

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A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120

Virology (New York, N.Y.), 2007-04, Vol.360 (2), p.329-340

2007

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The complete nucleotide sequence of a pathogenic molecular clone of simian immunodeficiency virus

AIDS research and human retroviruses, 1990-11, Vol.6 (11), p.1221-1231

1990

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Vaccine Protection by Live, Attenuated Simian Immunodeficiency Virus in the Absence of High-Titer Antibody Responses and High-Frequency Cellular Immune Responses Measurable in the Periphery

Journal of Virology, 2008-04, Vol.82 (8), p.4135-4148

2008

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Assorted Mutations in the Envelope Gene of Simian Immunodeficiency Virus Lead to Loss of Neutralization Resistance against Antibodies Representing a Broad Spectrum of Specificities

Journal of Virology, 2003-09, Vol.77 (18), p.9993-10003

2003

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ADCC Develops Over Time during Persistent Infection with Live-Attenuated SIV and Is Associated with Complete Protection against SIVmac251 Challenge

PLoS pathogens, 2012-08, Vol.8 (8), p.e1002890

2012

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Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys

Nature medicine, 2009-08, Vol.15 (8), p.901-906

2009

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Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques

PLoS pathogens, 2018-02, Vol.14 (2), p.e1006913-e1006913

2018

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Importance of the V1/V2 Loop Region of Simian-Human Immunodeficiency Virus Envelope Glycoprotein gp120 in Determining the Strain Specificity of the Neutralizing Antibody Response

Journal of Virology, 2008-11, Vol.82 (22), p.11054-11065

2008

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Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies

Molecular therapy, 2019-03, Vol.27 (3), p.650-660

2019

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SOSIP Trimer-Specific Antibodies Isolated from a Simian-Human Immunodeficiency Virus-Infected Monkey with versus without a Pre-blocking Step with gp41

Journal of virology, 2022-01, Vol.96 (2), p.e0158221-e0158221

2022

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My Uncle Charlie

Global CNS Transduction of Adult Mice by Intravenously Delivered rAAVrh.8 and rAAVrh.10 and Nonhuman Primates by rAAVrh.10

ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge

Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies

Vaccine protection against SIVmac239 acquisition

High concordance of ELISA and neutralization assays allows for the detection of antibodies to individual AAV serotypes

Comparative Characterization of Transfection- and Infection-Derived Simian Immunodeficiency Virus Challenge Stocks for In Vivo Nonhuman Primate Studies

Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection

Liver-Directed but Not Muscle-Directed AAV-Antibody Gene Transfer Limits Humoral Immune Responses in Rhesus Monkeys

SIV vpx is essential for macrophage infection but not for development of AIDS

Glycoengineering of AAV-delivered monoclonal antibodies yields increased ADCC activity

MHC heterozygote advantage in simian immunodeficiency virus-infected Mauritian cynomolgus macaques

A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120

The complete nucleotide sequence of a pathogenic molecular clone of simian immunodeficiency virus

Vaccine Protection by Live, Attenuated Simian Immunodeficiency Virus in the Absence of High-Titer Antibody Responses and High-Frequency Cellular Immune Responses Measurable in the Periphery

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

Assorted Mutations in the Envelope Gene of Simian Immunodeficiency Virus Lead to Loss of Neutralization Resistance against Antibodies Representing a Broad Spectrum of Specificities

Effect of CD8+ Lymphocyte Depletion on Virus Containment after Simian Immunodeficiency Virus SIVmac251 Challenge of Live Attenuated SIVmac239Δ3-Vaccinated Rhesus Macaques

ADCC Develops Over Time during Persistent Infection with Live-Attenuated SIV and Is Associated with Complete Protection against SIVmac251 Challenge

Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques

Importance of the V1/V2 Loop Region of Simian-Human Immunodeficiency Virus Envelope Glycoprotein gp120 in Determining the Strain Specificity of the Neutralizing Antibody Response

Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies

SOSIP Trimer-Specific Antibodies Isolated from a Simian-Human Immunodeficiency Virus-Infected Monkey with versus without a Pre-blocking Step with gp41

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

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